Zobrazeno 1 - 10
of 34
pro vyhledávání: '"C. D. Hufford"'
Publikováno v:
Pharmaceutical research. 3(3)
4-Methylprimaquine (4-MPQ), an 8-aminoquinoline antimalarial drug, was subjected to microbial metabolism studies in an effort to isolate, identify, and predict the probable mammalian metabolite(s). Preliminary screening with a number of strains of As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b73acda9904a06799e3a949aae600eb4
https://pubmed.ncbi.nlm.nih.gov/24271524
https://pubmed.ncbi.nlm.nih.gov/24271524
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ccce19f1d779ca1fb29376bc461595
https://doi.org/10.1002/chin.199526243
https://doi.org/10.1002/chin.199526243
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d17e4158640df946e8b7bf74b2eef18
https://doi.org/10.1002/chin.199802149
https://doi.org/10.1002/chin.199802149
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56456c98b7ea2a93d180972191c7406b
https://doi.org/10.1002/chin.199831192
https://doi.org/10.1002/chin.199831192
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe296f1fd5829619c38f9a755c2405d
https://doi.org/10.1002/chin.199929295
https://doi.org/10.1002/chin.199929295
Autor:
Andrew T. McPhail, I. A. Al-Meshal, Donald R. McPhail, Maher M. El-Domiaty, Farouk S. El-Feraly, Jaber S. Mossa, C. D. Hufford
Publikováno v:
Phytochemistry. 31:2863-2868
The aerial parts of Psiadia arabica yielded two new constituents: a flavone, 5,7,3′-trihydroxy-2′,4′,5′-trimethoxyflavone, the structure of which was derived from spectral data and chemical derivatization, and a kaurane diterpene named psiadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9988ad4798577af725cd1fa805323a9b
https://doi.org/10.1016/0031-9422(92)83648-i
https://doi.org/10.1016/0031-9422(92)83648-i
Publikováno v:
Current medicinal chemistry. 6(5)
The utilization of microbes as models for mammalian metabolism of xenobiotics has been well established since the concept was first introduced by Smith and Rosazza in the early seventies. The core assumption of this concept rests on the fact that fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2432e6f07a2a6350a88fd69ce357d6d
https://pubmed.ncbi.nlm.nih.gov/10101217
https://pubmed.ncbi.nlm.nih.gov/10101217
Publikováno v:
Pharmaceutical research. 12(10)
Deoxoartemisinin is a semisynthetic antimalarial with potential for treatment of multiple drug resistant malaria. Metabolism studies were conducted to aid in future drug development.Microbial model systems were employed which have been shown to be go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34d0028e63c5be2b9d682774f16ca89a
https://pubmed.ncbi.nlm.nih.gov/8584488
https://pubmed.ncbi.nlm.nih.gov/8584488
Publikováno v:
Pharmaceutical research. 11(7)
Microbial metabolism studies of the semisynthetic antimalarial anhydrodihydroartemisinin (1), have shown that it is metabolized by a number of microorganisms. Large scale fermentation with Streptomyces lavendulae L-105 and Rhizopogon species (ATCC 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1eb29a2b416f2b43600cd3fb2b4becc9
https://pubmed.ncbi.nlm.nih.gov/7937560
https://pubmed.ncbi.nlm.nih.gov/7937560
Publikováno v:
Pharmaceutical research. 9(5)
Microbial metabolism studies of crisnatol (1), a new DNA intercalator, has resulted in the isolation and characterization of a major metabolite identified as the C-1 hydroxylated crisnatol (2). The structure of the metabolite was established by compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96ef39def187ba8e6c8b551bc5011d03
https://pubmed.ncbi.nlm.nih.gov/1608892
https://pubmed.ncbi.nlm.nih.gov/1608892