Zobrazeno 1 - 10
of 169
pro vyhledávání: '"C. D. Garner"'
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Bloodstream infections are a major cause of morbidity and mortality and result in significant costs to health care systems. Rapid identification of the causative agent of bloodstream infections is critical for patient treatment and improved
Externí odkaz:
https://doaj.org/article/edcb877a2e464507815144db9c4abd4f
Publikováno v:
J Clin Microbiol
Rapid detection of antimicrobial resistance in both surveillance and diagnostic settings is still a major challenge for the clinical lab, compounded by the rapid evolution of antibiotic resistance mechanisms. This study compares four methods for the
Publikováno v:
Chemistry of Heterocyclic Compounds. 37:1375-1387
The reaction of a 2-[(dimethylamino)methyleneamino]pteridine, two 2-[(dimethylamino)methyleneamino]pyrimidines, and a 2-[(dimethylamino)methyleneamino]pyrido[2,3-d]pyrimidine with trimethylsilylethynylithium in the presence of benzyl chloroformate le
Autor:
Clive S. Butler, C D Garner, S.J. Ferguson, John M. Charnock, David J. Richardson, A J Thomson, Ben C. Berks
Publikováno v:
Biochemical Journal. 352:859-864
The periplasmic nitrate reductase (NAP) from Paracoccus pantotrophus is a soluble two-subunit enzyme (NapAB) that binds two haem groups, a [4Fe-4S] cluster and a bis(molybdopterin guanine dinucleotide) (MGD) cofactor that catalyses the reduction of n
Autor:
David J. Richardson, John M. Charnock, Clive S. Butler, David J. Lowe, C D Garner, Ben C. Berks, A J Thomson, S.J. Ferguson, Brian Bennett, Heather J. Sears, Ann Reilly
Publikováno v:
Biochemistry. 38:9000-9012
The periplasmic nitrate reductase from Paracoccus denitrificans is a soluble two-subunit enzyme which binds two hemes (c-type), a [4Fe-4S] center, and a bis molybdopterin guanine dinucleotide cofactor (bis-MGD). A catalytic cycle for this enzyme is p
Publikováno v:
European Journal of Biochemistry. 255:172-177
Neuronal-growth-inhibitory factor (GIF) is a metalloprotein specific to the central nervous system which has been linked to Alzheimer's disease. The high metal content, approximately seven metal atoms/protein molecule, and 70% sequence identity to ma
Autor:
J. F. W. Mosselmans, John M. Charnock, George R. Helz, C D Garner, K.E.R. England, David J. Vaughan, Richard A. D. Pattrick
Publikováno v:
Geochimica et Cosmochimica Acta. 61:2023-2036
X-ray absorption (XAS) and X-ray photoelectron spectroscopy (XPS) analysis of copper sulfide precipitated from aqueous solution at ambient temperatures reveals the existence of a metastable primitive structure that ages to a structure with the charac
Autor:
David J. Vaughan, C.V. Miller, J. F. W. Mosselmans, John M. Charnock, George R. Helz, Richard A. D. Pattrick, C D Garner
Publikováno v:
Geochimica et Cosmochimica Acta. 60:3631-3642
Molybdenum K-edge EXAFS (extended X-ray absorption fine structure) spectra yield new structural information about the chemical environment of Mo in high-Mo black shales and sediments. Two spectral types are found. The less common one, associated with
Autor:
Heather J. Sears, C D Garner, David J. Richardson, John M. Charnock, Ben C. Berks, Andrew J. Thomson, Brian Bennett, S.J. Ferguson
Publikováno v:
Biochemical Journal. 317:557-563
The molybdenum centre of the periplasmic respiratory nitrate reductase from the denitrifying bacterium Thiosphaera pantotropha has been probed using molybdenum K-edge X-ray absorption spectroscopy. The optimum fit of the Mo(VI) EXAFS suggests two =O,
Autor:
David J. Vaughan, Richard A. D. Pattrick, John M. Charnock, Paul F. Schofield, C D Garner, J. F. W. Mosselmans
Publikováno v:
Chemical Geology. 127:339-350
Experimental methods for performing X-ray absorption spectroscopy (XAS) on metal complexes in dilute aqueous solutions at temperatures up to 573 K are presented. The solutions are contained in silica tubes for study by X-rays of energies greater than