Zobrazeno 1 - 10
of 31
pro vyhledávání: '"C. Cudrey"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:429-435
The stereoselectivity of dog gastric and dog pancreatic lipases was investigated both in vitro, under simulated physiological conditions, and in vivo, during the digestion of a liquid test meal. In vitro it was observed that although both lipases had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d563f856e3b0bf62fd5523d73390ed6
https://doi.org/10.1016/s0968-0896(96)00251-9
https://doi.org/10.1016/s0968-0896(96)00251-9
Autor:
C. Cudrey, H. van Tilbeurgh, Christian Cambillau, Robert Verger, M P Egloff, Aurélie Nicolas, Chrislaine Martinez
Publikováno v:
Biochemistry. 33:83-89
Cutinases, a group of cutin degrading enzymes with molecular masses of around 22-25 kDa (Kolattukudy, 1984), are also able to efficiently hydrolyse triglycerides (De Geus et al., 1989; Lauwereys et al., 1991), but without exhibiting the interfacial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf6ee50188472eea2701f832785f8dc
https://doi.org/10.1021/bi00167a011
https://doi.org/10.1021/bi00167a011
Publikováno v:
Biochemistry. 32:13800-13808
We have reported previously that Cys103 (SHII) of human pancreatic lipase (HPL), unlike the nonessential Cys181 (SHI), was buried and inaccessible to classical water-soluble sulfhydryl reagents. The lipolytic activity of HPL was lost after the labeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd16d93756d85e78e1543591871fa7e4
https://doi.org/10.1021/bi00213a008
https://doi.org/10.1021/bi00213a008
Autor:
Helle Fabricius Woldike, C. Cudrey, Frédéric Carrière, Lars Thim, Guy Dodson, Esper Boel, Christian Cambillau, Francine Ferrato, A. Hjorth, David M. R. Lawson
Publikováno v:
Biochemistry. 32:4702-4707
Typically pancreatic lipases are characterized by the following properties: (1) they are activated by lipid/water interfaces (interfacial activation), (2) they are inhibited by bile salts but reactivated by colipase (a small activator protein), and (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab1a5e6c1a9b0f8f9e95eb63ade264b
https://doi.org/10.1021/bi00069a003
https://doi.org/10.1021/bi00069a003
Publikováno v:
Chirality. 5:24-30
In the present paper, a study on the stereoselectivity of 25 lipases of animal and microbial origin towards homogeneous prochiral triglycerides is presented. All the lipases tested catalyse the hydrolysis of the chemically alike but sterically nonequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeba638b5eb9e18494fd423b89a0816f
https://doi.org/10.1002/chir.530050106
https://doi.org/10.1002/chir.530050106
Autor:
H. van Tilbeurgh, Christian Cambillau, Helle Fabricius Woldike, Youssef Gargouri, C. Cudrey, Francine Ferrato, Frédéric Carrière, M P Egloff, Robert Verger, Lars Thim, N. Rugani, Guy Dodson, A. Hjorth, David M. R. Lawson, Esper Boel
Publikováno v:
Annals of the New York Academy of Sciences. 750
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712fa3a366c74b3ca68c2f88f34adc1a
https://pubmed.ncbi.nlm.nih.gov/7785848
https://pubmed.ncbi.nlm.nih.gov/7785848
Publikováno v:
Biochimica et biophysica acta. 1210(2)
Phosphonates mimicking the transition state which occurs during carboxyester hydrolysis were synthesized and investigated as potential inactivators of human pancreatic (HPL) and gastric (HGL) lipases. Their efficiency as inactivators was studied on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2f9775034f87e598450e46da064a2c
https://pubmed.ncbi.nlm.nih.gov/8280765
https://pubmed.ncbi.nlm.nih.gov/8280765
Autor:
Margarita G. Ivanova, Mustapha Aoubala, A. Hjorth, Helle Fabricius Woldike, N. Rugani, Frédéric Carrière, C. Cudrey, Francine Ferrato, Youssef Gargouri, C. Rivière, Robert Verger, H. van Tilbeurgh, M P Egloff, Christian Cambillau, David M. R. Lawson, Lars Thim, Guy Dodson, L. de la Fournière, A. De Caro, Esper Boel
Publikováno v:
Esterases, Lipases, and Phospholipases ISBN: 9781489909954
Apart from their general biological significance, lipolytic enzymes play an increasingly important role in biotechnology and medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ff939aa79a3394e2a38cb4441d0cf1
https://doi.org/10.1007/978-1-4899-0993-0_1
https://doi.org/10.1007/978-1-4899-0993-0_1
Publikováno v:
European journal of biochemistry. 204(3)
Both thiol groups of native human pancreatic lipase can react with the new hydrophobic sulfhydryl reagent 5-dodecyldithio-2-nitrobenzoic acid (Dod-S-NbS) in the absence of a denaturing agent. Here we describe for the first time the covalent and stoic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230a3840a785b3cfa631a3a10d54bfc0
https://pubmed.ncbi.nlm.nih.gov/1551387
https://pubmed.ncbi.nlm.nih.gov/1551387
Publikováno v:
Scopus-Elsevier
Journal of Medical Genetics
Journal of Medical Genetics, BMJ Publishing Group, 1995, 32 (3), pp.231-233. ⟨10.1136/jmg.32.3.231⟩
Journal of Medical Genetics
Journal of Medical Genetics, BMJ Publishing Group, 1995, 32 (3), pp.231-233. ⟨10.1136/jmg.32.3.231⟩
Charcot-Marie-Tooth disease type 1A (CMT1A), the most prevalent form of the peripheral hereditary neuropathies, has been associated with a duplication of a genomic segment of 1.5 Mb, located in 17p11.2. Recently, the same segment has been found to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf809ab6c534140d55c58994b0fabafa
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028956945&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028956945&partnerID=MN8TOARS