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Akademický článek
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Publikováno v:
Biochemical and Biophysical Research Communications. 323:315-322
Haematopoietic system represents the main source of haematopoietic stem cells and probably of multipotential adult progenitor cells and mesenchimal stem cells at first described as colony forming unit-fibroblast. Whereas there are many studies on the
Autor:
Maria Bayo, Silvia Casati, P Brantom, Yann Sibiri, Ralph E. Parchment, Greet Schoeters, B. Albella, C. Croera, Juan A. Bueren, Dominique Parent-Massin, Rosette Van Den Heuvel, Augusto Pessina, Laura Gribaldo
Publikováno v:
Alternatives to Laboratory Animals. 30:75-79
In a prevalidation study, a Standard Operating Procedure (SOP) for human and mouse in vitro tests was developed, for evaluating the potential haematotoxicity of xenobiotics in terms of their direct, adverse effects on the myeloid colony-forming unit
Autor:
Augusto Pessina, Juan A. Bueren, Dominique Parent-Massin, Laura Gribaldo, G Gagliardi, C. Croera, Silvia Casati, B. Albella, P. Foti, Ralph E. Parchment, R. Van Den Heuvel, P Brantom, Y. Sibiril
Publikováno v:
Toxicology in Vitro. 15:729-740
This report describes an international prevalidation study conducted to optimise the Standard Operating Procedure (SOP) for detecting myelosuppressive agents by CFU-GM assay and to study a model for predicting (by means of this in vitro hematopoietic
Autor:
A. Raimondi, P. Foti, Emilio Berti, C. Croera, Maria Grazia Neri, Amilcare Cerri, M. Piccirillo, Augusto Pessina
Publikováno v:
Cell Proliferation. 34:243-252
In the panorama of the numerous established cell lines, the human keratinocyte line HaCaT has a very interesting feature, having a close similarity in functional competence to normal keratinocytes. This cell line has been used in many studies as a pa
Autor:
Augusto Pessina, C. Croera, Silvio R. Bareggi, F. Guizzardi, Loredana Cavicchini, A. Bonomi, Elisa Turlizzi
Publikováno v:
Pharmacopsychiatry. 39:20-22
Introduction Atypical antipsychotics may lead to agranulocytosis because of the apoptosis caused by cells binding nitrenium molecules. Studies showing the direct myelotoxicity of clozapine were undertaken years ago using different assays, and thus it
Autor:
Laura Gribaldo, I. Malerba, Dominique Parent-Massin, A. de Smedt, R. Van Den Heuvel, S. Gomez, C. Croera, Augusto Pessina, B. Albella, Y. Sibiril, Silvia Casati
Megakaryocytopoiesis gives rise to platelets by proliferation and differentiation of lineage-specific progenitors, identified in vitro as Colony Forming Unit-Megakaryocytes (CFU-Mk). The aim of this study was to refine and optimize the in vitro Stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75afc3c80c1144ee6393915b9c23ba51
http://hdl.handle.net/2434/54106
http://hdl.handle.net/2434/54106
Autor:
Arianna Bonomi, Laura Gribaldo, Silvia Casati, E. Marafante, C. Croera, Augusto Pessina, Fabrizio Palitti, A. Collotta
Publikováno v:
Cell proliferation. 40(4)
Objective: The susceptibility of two cell lines, WEHI‐3B myelomonocytic leukaemia and its variant Ciprofloxacin‐resistant WEHI‐3B/CPX to undergo apoptosis induced by Ciprofloxacin was studied and compared. Materials and methods: Apoptosis was c
Autor:
C. Croera, Fabiana Guizzardi, Arianna Bonomi, Maria Grazia Neri, Nicoletta Savalli, Loredana Cavicchini, Lucia Guido, Laura Daprai, Elisa Turlizzi, Augusto Pessina
Publikováno v:
Cell research. 16(3)
The very different effects of Cholera Toxin (CT) on cell growth and proliferation may depend on the type of ganglioside receptors in cell membranes and different signal transduction mechanisms triggered, but other functions related to the drug resist
Autor:
Laura Gribaldo, C. Croera, Maria Bayo, Augusto Pessina, Loredana Cavicchini, Maria Grazia Neri, Ilaria Malerba, Laura Passardi
Publikováno v:
Alternatives to laboratory animals : ATLA. 32(1)
In a recent prevalidation study, the use of a methylcellulose colony-forming unit-granulocyte/macrophage (CFU-GM) macroassay for two independent in vitro tests (human and murine cell based) was suggested for quantifying the potential haematotoxicity