Zobrazeno 1 - 10
of 24
pro vyhledávání: '"C. Crasta"'
Publikováno v:
Redox Biology, Vol 74, Iss , Pp 103228- (2024)
Therapy-induced senescent tumor cells have emerged as significant drivers of tumor recurrence and disease relapse. Interestingly, reactive oxygen species (ROS) production and its associated redox signaling networks are intertwined with initiation and
Externí odkaz:
https://doaj.org/article/e31594045fb84e5f95e206917464a9a8
Autor:
Karen C. Crasta, Jayantha Gunaratne, John E. Connolly, Xiaomeng Wang, Indrajit Sinha, Boon T. Chua, Juliana T.S. Ho, James B.K. Khoo, Jill S.L. Wong, Yirong Sim, Kong W. Ong, Tee B.K. Tan, Elaine H. Lim, Han C. Chong, Jiamila Maimaiti, Kah J. Lim, Madhura Kulkarni, Bijin Au, Suat P. Neo, Ke Guo, Bing Cheng, Alex X.F. Wong, Monique N.H. Luijten, Rekha Jakhar
The most commonly utilized class of chemotherapeutic agents administered as a first-line therapy are antimitotic drugs; however, their clinical success is often impeded by chemoresistance and disease relapse. Hence, a better understanding of the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3d6ef3933b5b8d0213dc42e86e3311
https://doi.org/10.1158/1541-7786.c.6541024.v1
https://doi.org/10.1158/1541-7786.c.6541024.v1
Autor:
Karen C. Crasta, Jayantha Gunaratne, John E. Connolly, Xiaomeng Wang, Indrajit Sinha, Boon T. Chua, Juliana T.S. Ho, James B.K. Khoo, Jill S.L. Wong, Yirong Sim, Kong W. Ong, Tee B.K. Tan, Elaine H. Lim, Han C. Chong, Jiamila Maimaiti, Kah J. Lim, Madhura Kulkarni, Bijin Au, Suat P. Neo, Ke Guo, Bing Cheng, Alex X.F. Wong, Monique N.H. Luijten, Rekha Jakhar
S1. Post-slippage cells arrest at G1 as tetraploid multinucleated cells. S2. Correlation of multinucleation and senescence post-slippage in response to various anti-mitotic drugs. S3. In vivo association of senescence and anti-mitotic drug treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c6e2cddbb31105ba560c0dba8d550c
https://doi.org/10.1158/1541-7786.22515274
https://doi.org/10.1158/1541-7786.22515274
Akademický článek
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Autor:
Laveena C Crasta, Shailashri V. T.
Background /Purpose: Talent management is the kernel of human resource management, the process of procurement of the right people to be absorbed by a company based on its business requirements. The surge to absorb the right competency in the global m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d4c02fde97c5b87c4bd1d5bb55f2f
Publikováno v:
Guan, L, Crasta, K C & Maier, A B 2022, ' Assessment of cell cycle regulators in human peripheral blood cells as markers of cellular senescence ', Ageing Research Reviews, vol. 78, 101634, pp. 1-16 . https://doi.org/10.1016/j.arr.2022.101634
Cellular senescence has gained increasing interest during recent years, particularly due to causal involvement in the aging process corroborated by multiple experimental findings. Indeed, cellular senescence considered to be one of the hallmarks of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089b72b86f62f2d1ac4325a8d1b4cf62
https://doi.org/10.1016/j.arr.2022.101634
https://doi.org/10.1016/j.arr.2022.101634
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1769
Lagging chromosomes that arise after chromosome mis-segregation during cell division can be encapsulated within small structures known as micronuclei. A link between whole-chromosome mis-segregation and chromothripsis has been demonstrated via micron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7183364cfd1a259b4065362a2ca7d147
https://pubmed.ncbi.nlm.nih.gov/29564825
https://pubmed.ncbi.nlm.nih.gov/29564825
Autor:
Mark S. Butler, Siewbee Ng, K. Yoganathan, Shugeng Cao, Antony D. Buss, Srinivasulu Aitipamula, Stephen R. Whitton, Sharon C. Crasta
Publikováno v:
Tetrahedron. 64:10181-10187
Bioassay-guided isolation using an MRSA whole cell assay yielded four novel benzophenone dimers, microsphaerins A-D (1-4), from two Singapore isolates of the soil anamorph Microsphaeropsis sp. The structures of 1-4 were elucidated on the basis of spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab595e21f0497fb24feaa9e1c23403a9
https://doi.org/10.1016/j.tet.2008.08.038
https://doi.org/10.1016/j.tet.2008.08.038
Autor:
C. Crasta, Ricky O'Brien, Nicholas Hardcastle, Kathryn Szymura, Jeremy T. Booth, Carol Haddad, Vincent Caillet, Paul J. Keall
Publikováno v:
Medical Physics. 43:3710-3711
Purpose: To assess endo-bronchial electromagnetic beacon insertion and to quantify the geometric accuracy of using beacons as a surrogate for tumour motion in real-time multileaf collimator (MLC) tracking of lung tumours. Methods: The LIGHT SABR tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f1dad32ac4da8d30237380d6ac5974
https://doi.org/10.1118/1.4957299
https://doi.org/10.1118/1.4957299
Autor:
Kia-Ngee Low, Shugeng Cao, Sharon C. Crasta, and Antony D. Buss, Robert P. Glover, Siewbee Ng, Mark S. Butler
Publikováno v:
Journal of Natural Products. 69:707-709
Bioassay-directed fractionation using a glucocorticoid receptor assay led to the isolation of two new, weakly active polyprenylated acylphloroglucinol derivatives, sundaicumones A (1) and B (2), from the leaves of Calophyllum sundaicum collected in S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969a4cf1af730f85c85958b5694d5742
https://doi.org/10.1021/np050528n
https://doi.org/10.1021/np050528n