Zobrazeno 1 - 10
of 324
pro vyhledávání: '"C. Cookson"'
Autor:
Leah Cuthbertson, Ulrike Löber, Jonathan S. Ish-Horowicz, Claire N. McBrien, Colin Churchward, Jeremy C. Parker, Michael T. Olanipekun, Conor Burke, Aisling McGowan, Gwyneth A. Davies, Keir E. Lewis, Julian M. Hopkin, Kian Fan Chung, Orla O’Carroll, John Faul, Joy Creaser-Thomas, Mark Andrews, Robin Ghosal, Stefan Piatek, Saffron A. G. Willis-Owen, Theda U. P. Bartolomaeus, Till Birkner, Sarah Dwyer, Nitin Kumar, Elena M. Turek, A. William Musk, Jennie Hui, Michael Hunter, Alan James, Marc-Emmanuel Dumas, Sarah Filippi, Michael J. Cox, Trevor D. Lawley, Sofia K. Forslund, Miriam F. Moffatt, William. O. C. Cookson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Microbial communities at the airway mucosal barrier are conserved and highly ordered, in likelihood reflecting co-evolution with human host factors. Freed of selection to digest nutrients, the airway microbiome underpins cognate management o
Externí odkaz:
https://doaj.org/article/fa0a86718fb4447f9b20ab7e4ec9f322
Autor:
Yakinthi Chrisochoidou, Rajat Roy, Pooyeh Farahmand, Guadalupe Gonzalez, Jennifer Doig, Lukas Krasny, Ella F. Rimmer, Anne E Willis, Marion MacFarlane, Paul H. Huang, Neil O. Carragher, Alison F. Munro, Daniel J. Murphy, Kirill Veselkov, Michael J. Seckl, Miriam F. Moffatt, William O. C. Cookson, Olivier E. Pardo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-20 (2023)
Abstract Mesothelioma is an aggressive cancer of the mesothelial layer associated with an extensive fibrotic response. The latter is in large part mediated by cancer-associated fibroblasts which mediate tumour progression and poor prognosis. However,
Externí odkaz:
https://doaj.org/article/aaf6d7ac3e1a4d1b86de96ee85ac0b92
Autor:
Saffron A. G. Willis-Owen, Clara Domingo-Sabugo, Elizabeth Starren, Liming Liang, Maxim B. Freidin, Madeleine Arseneault, Youming Zhang, Shir Kiong Lu, Sanjay Popat, Eric Lim, Andrew G. Nicholson, Yasser Riazalhosseini, Mark Lathrop, William O. C. Cookson, Miriam F. Moffatt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Lung cancer is the most frequent cause of cancer death worldwide. It affects more men than women, and men generally have worse survival outcomes. We compared gene co-expression networks in affected and unaffected lung tissue from 126 consecu
Externí odkaz:
https://doaj.org/article/984df0ae21224581b348c62efb1c4fcb
Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis
Autor:
David T. J. Broderick, David W. Waite, Robyn L. Marsh, Carlos A. Camargo, Paul Cardenas, Anne B. Chang, William O. C. Cookson, Leah Cuthbertson, Wenkui Dai, Mark L. Everard, Alain Gervaix, J. Kirk Harris, Kohei Hasegawa, Lucas R. Hoffman, Soo-Jong Hong, Laurence Josset, Matthew S. Kelly, Bong-Soo Kim, Yong Kong, Shuai C. Li, Jonathan M. Mansbach, Asuncion Mejias, George A. O’Toole, Laura Paalanen, Marcos Pérez-Losada, Melinda M. Pettigrew, Maxime Pichon, Octavio Ramilo, Lasse Ruokolainen, Olga Sakwinska, Patrick C. Seed, Christopher J. van der Gast, Brandie D. Wagner, Hana Yi, Edith T. Zemanick, Yuejie Zheng, Naveen Pillarisetti, Michael W. Taylor
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Introduction: The airway microbiota has been linked to specific paediatric respiratory diseases, but studies are often small. It remains unclear whether particular bacteria are associated with a given disease, or if a more general, non-specific micro
Externí odkaz:
https://doaj.org/article/c272f2281790452aa37d24bfbb50f88d
Autor:
Leah Cuthbertson, Stephen W C Oo, Michael J Cox, Siew-Kim Khoo, Des W Cox, Glenys Chidlow, Kimberley Franks, Franciska Prastanti, Meredith L Borland, James E Gern, David W Smith, Joelene A Bizzintino, Ingrid A Laing, Peter N Le Souëf, Miriam F Moffatt, William O C Cookson
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223990 (2019)
Acute viral wheeze in children is a major cause of hospitalisation and a major risk factor for the development of asthma. However, the role of the respiratory tract microbiome in the development of acute wheeze is unclear. To investigate whether seve
Externí odkaz:
https://doaj.org/article/9744bb3b496547a790bdfc405d1bc6f7
Autor:
Steven A Cowman, Phillip James, Robert Wilson, William O C Cookson, Miriam F Moffatt, Michael R Loebinger
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208018 (2018)
The diagnosis of pulmonary non-tuberculous mycobacterial disease (pNTM) is dependent on the isolation of NTM in culture, which is prone to overgrowth and contamination and may not capture the diversity of mycobacteria present, including rare or unide
Externí odkaz:
https://doaj.org/article/df4214ce644b497b99669afcad768f72
Autor:
Bushra Ahmed, Michael J Cox, Leah Cuthbertson, Phillip L James, William O C Cookson, Jane C Davies, Miriam F Moffatt, Andrew Bush
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201156 (2018)
RATIONALE:The lower airway microbiota is important in normal immunological development and chronic lung diseases (CLDs). Young children cannot expectorate and because of the uncertainty whether upper airway samples reflect the lower airway microbiota
Externí odkaz:
https://doaj.org/article/d0aa6478a24f42efb188d4a7dbf6f231
Autor:
Michael J Cox, Elena M Turek, Catherine Hennessy, Ghazala K Mirza, Phillip L James, Meg Coleman, Andrew Jones, Robert Wilson, Diana Bilton, William O C Cookson, Miriam F Moffatt, Michael R Loebinger
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170622 (2017)
BACKGROUND:Bronchiectasis is accompanied by chronic bronchial infection that may drive disease progression. However, the evidence base for antibiotic therapy is limited. DNA based methods offer better identification and quantification of microbial co
Externí odkaz:
https://doaj.org/article/e8c2345d2df24e73b5d786c88430113e
Autor:
Markus Hilty, Conor Burke, Helder Pedro, Paul Cardenas, Andy Bush, Cara Bossley, Jane Davies, Aaron Ervine, Len Poulter, Lior Pachter, Miriam F Moffatt, William O C Cookson
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8578 (2010)
A rich microbial environment in infancy protects against asthma [1], [2] and infections precipitate asthma exacerbations [3]. We compared the airway microbiota at three levels in adult patients with asthma, the related condition of COPD, and controls
Externí odkaz:
https://doaj.org/article/e2d09cb56f5c42b084692551efb517d1
Autor:
Phillip L, James, Julie, Cannon, Christopher M, Barber, Laura, Crawford, Heather, Hughes, Meinir, Jones, Joanna, Szram, Steven, Cowman, William O C, Cookson, Miriam F, Moffatt, Paul, Cullinan
Publikováno v:
Thorax
Background Outbreaks of hypersensitivity pneumonitis (HP) are not uncommon in workplaces where metal working fluid (MWF) is used to facilitate metal turning. Inhalation of microbe-contaminated MWF has been assumed to be the cause, but previous invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76967c33a83b26dcdc283e50208924ef
https://pubmed.ncbi.nlm.nih.gov/28851756
https://pubmed.ncbi.nlm.nih.gov/28851756