Zobrazeno 1 - 10
of 28
pro vyhledávání: '"C. C. T. Smith"'
Publikováno v:
Platelets. 13:267-271
We examined the effects of the alpha(1)-adrenoreceptor blockers naftopidil and doxazosin and the Ca(2+) antagonist nifedipine on platelet function with reference to stimulus-induced thromboxane (TxB(2)) generation and platelet-derived growth factor (
Autor:
C. C. T. Smith, D. J. Betteridge
Publikováno v:
Platelets. 11:395-400
Collagen-induced (5-80 microg/ml) efflux of free noradrenaline (NA) and adrenaline (Ad) from platelets in platelet-rich plasma was compared in normal human subjects and heterozygous familial hypercholesterolaemic (FH) patients. Stimulated release of
Publikováno v:
Platelets. 10:253-256
F(2)-isoprostanes are prostaglandin (PG) F(2)-like compounds formed via non-enzymatic peroxidation of arachidonic acid, although some F(2)-isoprostane production may be cyclo-oxygenase (COX)-mediated. Of these substances 8-epi-prostaglandin F(2)alpha
Autor:
Marie-Louise Dubelaar, Mark I. M. Noble, A. J. Drake-Holland, C. C. T. Smith, M. Steinfath, Will A. Coumans, G. J. Van Der Vusse
Publikováno v:
Molecular and Cellular Biochemistry. 183:215-219
Surgical ablation of extrinsic cardiac nerve fibers results in a chronically denervated state of the left ventricle of the heart. The present study was performed to elucidate the effect of a period of 5 weeks of chronic denervation on cardiac catecho
Collagen stimulated release of serotonin by human platelets includes a sulphate conjugated component
Autor:
C. C. T. Smith
Publikováno v:
Platelets. 7:231-236
Collagen (5-160 μg/ml) induced release of free and sulphate conjugated serotonin (5-HT) from platelets in platelet-rich plasma (PRP) was examined in normal human subjects. Collagen stimulated release of free 5-HT to the plasma (platelet-poor; PPP) i
Autor:
C. C. T. Smith, M. Hayes, S. Chayen, D. A. Higgins, P. Priyakumar, Peter Salmon, Spencer Stephen Kee, Anne Manyande, S. Phillips
Publikováno v:
Scopus-Elsevier
It has been argued that surgery is a form of psychological stress, and that the response to it should therefore be modifiable by psychological means. To test this hypothesis, we assessed the effect of preoperative relaxation instructions on endocrine
Publikováno v:
Clinical science (London, England : 1979). 91(1)
1. In view of the importance of 5-hydroxytryptamine in coronary thrombosis, we wanted to know whether a potentially protective decrease in platelet 5-hydroxytryptamine could be achieved by treatment with an inhibitor of 5-hydroxytryptamine uptake, fl
Publikováno v:
BMJ (Clinical research ed.). 310(6983)
Oily fish contains large quantities of the long chain n-3 ((omega)-3) polyunsaturated fatty acids (eicosapentaenoic acid (C20:5) and docosahexaenoic acid (C22:6)). Low rates of coronary heart disease in various populations with high intakes of fish s
Publikováno v:
British journal of clinical pharmacology. 30(1)
1. Dopexamine is a novel analogue of dopamine which is free of alpha-adrenoceptor activity and is of therapeutic value in chronic heart failure. The effects of dopexamine on the in vitro function of platelets from 10 healthy subjects at rest, after e
Publikováno v:
Journal of Cardiovascular Pharmacology. 20:S77