Zobrazeno 1 - 10
of 36
pro vyhledávání: '"C. C. Kartha"'
Autor:
C. L. Karthika, Vani Venugopal, B. J. Sreelakshmi, S. Krithika, Jaya Mary Thomas, Mathew Abraham, C. C. Kartha, Arumugam Rajavelu, S. Sumi
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-19 (2023)
Abstract Background Cerebral arteriovenous malformations (cAVM) are a significant cause of intracranial hemorrhagic stroke and brain damage. The arteriovenous junctions in AVM nidus are known to have hemodynamic disturbances such as altered shear str
Externí odkaz:
https://doaj.org/article/5c34a25f38f841ea959194f99e663a08
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Advancements in systems biology have resulted in the development of network pharmacology, leading to a paradigm shift from “one-target, one-drug” to “target-network, multi-component therapeutics”. We employ a chimeric approach involv
Externí odkaz:
https://doaj.org/article/6f53b632952146e7b40af56c91c87711
Autor:
V Chitra Sree Varadarajan, S Ajit Mullasari, S Vijayakumar Subban, V Suma M Victor, M Poornima, S Jayanthi, R Surya Ramachandran, C C Kartha
Publikováno v:
European Heart Journal. 44
Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Institute of Cardiovascular disease, Madras Medical Mission Background Type 2 Diabetes (DM) is a pro-inflammatory state in the pathogenesis of Atherosclerosis with the p
Autor:
R Dhanya, C C Kartha
Publikováno v:
Molecular and Cellular Biochemistry. 476:3879-3887
Citrus flavonoids particularly quercetin which is abundant in grapefruit, onion, green tea, berries etc. are known to have a protective effect on oxidative stress. Pancreatic β cells which synthesize and secrete insulin are prone to oxidative stress
Autor:
Thushara Thulaseedharan, Surya Ramachandran, M. Radhakrishna Pillai, C C Kartha, Santhosh Kumar Thankayyan Retnabai, Vinitha Anandan, Ajit S. Mullasari, Abdul Jaleel
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 5, Pp 305-322 (2021)
FASEB BioAdvances
FASEB BioAdvances
Macrophage apoptosis is a key contributor to the progression of atherosclerosis. Cyclophilin A, a monocyte secretory protein associated with the initiation of atherosclerosis has an inherent nuclease activity. This study reports the mechanism by whic
Publikováno v:
Heart Failure Reviews. 24:255-267
Mitochondrial dysfunction is widely recognized as a major factor for the progression of cardiac failure. Mitochondrial uptake of metabolic substrates and their utilization for ATP synthesis, electron transport chain activity, reactive oxygen species
Autor:
R, Dhanya, C C, Kartha
Publikováno v:
Molecular and cellular biochemistry. 476(11)
Citrus flavonoids particularly quercetin which is abundant in grapefruit, onion, green tea, berries etc. are known to have a protective effect on oxidative stress. Pancreatic β cells which synthesize and secrete insulin are prone to oxidative stress
Publikováno v:
Molecular and cellular biochemistry. 476(1)
Endothelium of blood vessels is continuously exposed to various hemodynamic forces. Flow-mediated epigenetic plasticity regulates vascular endothelial function. Recent studies have highlighted the significant role of mechanosensing-related epigenetic
Autor:
V. R. Kutty, C C Kartha, M. Radhakrishna Pillai, Surya Ramachandran, Vinitha Anandan, Ajit S. Mullasari
Publikováno v:
Clinical Science. 132:719-738
Growing evidence implicates cyclophilin A secreted by vascular wall cells and monocytes as a key mediator in atherosclerosis. Cyclophilin A in addition to its proliferative effects, during hyperglycemic conditions, increases lipid uptake in macrophag
Autor:
G. Sanjay, Neha Deora, C C Kartha, Vikas Kumar, Kumar T. R. Santhosh, K. Kshemada, Raj S. S. Binil, E. M. Anandan, kumar A. Aneesh, M. S. Valiathan, T. S. Muraleedharan, R. S Mony, Abdul Jaleel, Kumar G. S. Ajith
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports
Scientific Reports
We evaluated the cardioprotective effect of Amalaki Rasayana (AR), a rejuvenating Ayurvedic drug prepared from Phyllanthusemblica fruits in the reversal of remodeling changes in pressure overload left ventricular cardiac hypertrophy (LVH) and age-ass