Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C. C. Gispen-de Wied"'
Autor:
C. C. Gispen-de Wied, Marieke Biegstraaten, Carla E. M. Hollak, Yvonne Schuller, Violeta Stoyanova-Beninska
Publikováno v:
Drugs
Drugs, 77(13), 1461-1472. Adis International Ltd
Drugs, 77(13), 1461-1472. Adis International Ltd
Introduction Authorization of orphan medicinal products (OMPs) is often based on studies with several methodological shortcomings. Hence, data are difficult to interpret and efficacy does not always correspond to real-world effectiveness. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743eb538480be1244daf365f52bc35bc
https://doi.org/10.1007/s40265-017-0788-z
https://doi.org/10.1007/s40265-017-0788-z
Autor:
G. J. M. W. van Thiel, C. C. Gispen-de Wied, J.J.M. van Delden, Nancy S. Breekveldt, Rosemarie D. L. C. Bernabe
Publikováno v:
Current Medical Research and Opinion, 35(4), 637. Informa Healthcare
Background: Within the EU, regulators are obliged to take ethical issues into consideration during marketing authorization deliberation. The goal of this manuscript is to identify what kinds of ethical issues regulators encounter during marketing aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec42513f73c1822ac768e5c22dcff3e
https://dspace.library.uu.nl/handle/1874/381166
https://dspace.library.uu.nl/handle/1874/381166
Autor:
C C M, Welten, M W J, Koeter, T, Wohlfarth, J G, Storosum, W, van den Brink, C C, Gispen-de Wied, H G M, Leufkens, D A J P, Denys
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 25(7)
We examined the role of placebo response in acute mania trials. Specifically, whether placebo response: (1) predicts treatment effect, (2) can be predicted by patient and study characteristics, and (3) can be predicted by a parsimonious model. We per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d02c808f1e4baca091a70b256d602472
https://pubmed.ncbi.nlm.nih.gov/25907248
https://pubmed.ncbi.nlm.nih.gov/25907248
Autor:
C. C. Gispen-de Wied, Chantal Kemner, Herman Westenberg, René S. Kahn, Bob Oranje, Marinus N. Verbaten
Publikováno v:
Journal of Psychopharmacology. 18:388-394
Schizophrenic patients show a loss of sensory gating, which is reflected in a reduced P50 suppression. Because most of the symptoms inschizophrenia can be reduced by antagonists of the dopaminergic (D2) system, the loss in sensory gating might be rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7ecf6e817f839bb4f7a6c76dd141cb
https://doi.org/10.1177/026988110401800310
https://doi.org/10.1177/026988110401800310
Publikováno v:
Clinical Chemistry. 42:1238-1242
We conducted experiments to demonstrate that the determination of dexamethasone in saliva is a valuable tool to assess dexamethasone concentrations in the body after administration of this synthetic corticosteroid. After extraction of saliva, a RIA i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4d6c00bb8bc2f4289f0c591207a1fb
https://doi.org/10.1093/clinchem/42.8.1238
https://doi.org/10.1093/clinchem/42.8.1238
Publikováno v:
The journal of nutrition, healthaging. 13(4)
To evaluate the validity of biomarkers that are currently being proposed as potential surrogate endpoints in AD clinical trials with the aid of the "Quantitative Surrogate Validation Level of Evidence Schema" (QSVLES) proposed by Lassere et.al. (1).A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fef3d0b8408207ee747d5edf2ae4c2
https://pubmed.ncbi.nlm.nih.gov/19300886
https://pubmed.ncbi.nlm.nih.gov/19300886
Autor:
Herman Westenberg, René S. Kahn, Marinus N. Verbaten, Chantal Kemner, Bob Oranje, C. C. Gispen-de Wied
Publikováno v:
Journal of psychopharmacology (Oxford, England). 20(6)
Patients with schizophrenia exhibit diverse cognitive deficits, one of which is a loss of the ability to focus attention. According to the revised dopamine hypothesis of schizophrenia both an increased mesolimbic and a decreased prefrontal dopaminerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0393a1ca53aaa7106fae0ea152f62a62
https://pubmed.ncbi.nlm.nih.gov/16478755
https://pubmed.ncbi.nlm.nih.gov/16478755
Autor:
D, Cohen, C C, Gispen-de Wied
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 147(21)
Three male schizophrenia patients, aged 41, 40 and 61 years respectively, who had undergone treatment without a satisfactory result, were treated with the antipsychotic clozapine. Diabetes mellitus developed within a period of several months to sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f2595dde31796098979238bbb8f39c0
https://pubmed.ncbi.nlm.nih.gov/12811967
https://pubmed.ncbi.nlm.nih.gov/12811967
Publikováno v:
Clinical chemistry. 42(8 Pt 1)
We conducted experiments to demonstrate that the determination of dexamethasone in saliva is a valuable tool to assess dexamethasone concentrations in the body after administration of this synthetic corticosteroid. After extraction of saliva, a RIA i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ace28b66e2accf40fa1c613e3861f0dc
https://pubmed.ncbi.nlm.nih.gov/8697583
https://pubmed.ncbi.nlm.nih.gov/8697583
Publikováno v:
Clinical Pharmacology & Therapeutics. 83:812-812
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d85954f2b19252424af09eba2ad8b2aa
https://doi.org/10.1038/sj.clpt.6100338
https://doi.org/10.1038/sj.clpt.6100338