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Autor:
Glenna C. Burmer, Nancy J. Linford, Vasiliki Demas, Peter S. Rabinovitch, Richard P. Beyer, Rozlyn A. Krajcik, Virginia L. Malloy, Katherine A. Gollahon
Publikováno v:
Aging Cell. 6:673-688
Sustained caloric restriction (CR) extends lifespan in animal models but the mechanism and primary tissue target(s) have not been identified. Gene expression changes with aging and CR were examined in both heart and white adipose tissue (WAT) of Fisc
Publikováno v:
Journal of the American Academy of Dermatology. 29:321-325
Buschke-Löwenstein-type giant penile condyloma developed in a human immunodeficiency virus-negative, 25-year-old man after 4 years of intermittent cyclosporine therapy (5 mg/kg/day) for pustular psoriasis. Microscopic examination showed multifocal a
Publikováno v:
Journal of Urology. 149:374-377
A 53-year-old man presented with recurrent squamous cell carcinoma, and dysplasia of the scrotum and penis. Risk factors included psoralen and ultraviolet radiation therapy for psoriasis, and x-ray therapy for primary lymphoma of the groin. Three dif
Autor:
Douglas S. Levine, Glenna C. Burmer, Michael B. Kimmey, Cyrus E. Rubin, Patrick J. Dean, Teresa A. Brentnall, Peter S. Rabinovitch, Rodger C. Haggitt, David R. Perera, Allyn C. Stevens
Publikováno v:
Gastroenterology. 103:1611-1620
The objective of the present study was to determine whether abnormal epithelial DNA content (aneuploidy) in colonic biopsy specimens from ulcerative colitis (UC) patients correlated with and predicted histological progression to dysplasia. Aneuploidy
Autor:
Allyn C. Stevens, Glenna C. Burmer, Peter S. Rabinovitch, Cyrus E. Rubin, Rodger C. Haggitt, Teresa A. Brentnall, David A. Crispin, Venkateswara R. Kolli
Publikováno v:
Gastroenterology. 103:1602-1610
Neoplastic progression in patients with chronic ulcerative colitis (UC) is characterized by the development of epithelial dysplasia, which is accompanied by genetic abnormalities that can be detected by flow cytometric and molecular biologic methods.
Publikováno v:
Environmental Health Perspectives
Sporadic colon carcinomas, carcinomas arising in chronic ulcerative colitis, and pancreatic adenocarcinomas have been analyzed for the presence of c-Ki-ras mutations by a combination of histological enrichment, cell sorting, polymerase chain reaction
Publikováno v:
Nucleic Acids Research. 19:3055-3060
We describe a modification of a polymerase chain reaction method called 'targeted gene walking' that can be used for the amplification of unknown DNA sequences adjacent to a short stretch of known sequence by using the combination of a single, target
Publikováno v:
American Journal of Clinical Pathology. 94:554-560
Cervical samples from 270 women referred by area physicians were analyzed for the presence of human papillomavirus (HPV) types 6, 11, 16, and 18 by the polymerase chain reaction (PCR) followed by Southern hybridization. Samples from 154 patients were
Autor:
Sunil Nagpal, Thomas P. Burris, George E. Sandusky, Glenna C Burmer, Subba R. Chintalacharuvu
Publikováno v:
Arthritis and rheumatism. 56(4)