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pro vyhledávání: '"C. Blumstein"'
Akademický článek
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Autor:
Peter Seiler, L. Jacob, Swen Seeland, S. Diethelm, N. Tidten-Luksch, Jean-Philippe Surivet, M. Wicki, Georg Rueedi, Jean-Luc Specklin, Michel Enderlin-Paput, Christian Hubschwerlen, Azely Mirre, R. Lange, G. Mathieu, Christine Schmitt, C. Herrmann, Philippe Panchaud, A.-C. Blumstein, A. Mac Sweeney, F. Masse, Daniel Ritz, Jean-Christophe Gauvin, Carmela Gnerre
Publikováno v:
Journal of Medicinal Chemistry. 63:66-87
UDP-3-O-((R)-3-hydroxymyristoyl)-N-glucosamine deacetylase (LpxC) is as an attractive target for the discovery and development of novel antibacterial drugs to address the critical medical need created by multidrug resistant Gram-negative bacteria. By
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae4ad619b6cf3e0f3c6f741f71c0456
https://doi.org/10.1021/acs.jmedchem.9b01604
https://doi.org/10.1021/acs.jmedchem.9b01604
Autor:
Michel Enderlin-Paput, Swen Seeland, A.-C. Blumstein, Daniel Ritz, Peter Seiler, R. Lange, Jean-Philippe Surivet, Christine Schmitt, F. Masse, Jean-Christophe Gauvin, S. Diethelm, L. Jacob, Charlyse Herrmann, Carmela Gnerre, Hans H. Locher, G. Mathieu, Azely Mirre, Georg Rueedi, Philippe Panchaud
Publikováno v:
Journal of medicinal chemistry. 63(1)
LpxC inhibitors were optimized starting from lead compounds with limited efficacy and solubility and with the goal to provide new options for the treatment of serious infections caused by Gram-negative pathogens in hospital settings. To enable the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8724e5d5a4339ed1cc3153b7f635fcc4
https://pubmed.ncbi.nlm.nih.gov/31804829
https://pubmed.ncbi.nlm.nih.gov/31804829
Autor:
Markus Gude, Georg Rueedi, Thomas Pfeifer, Christian Hubschwerlen, Daniel Ritz, Thierry Kimmerlin, L. Jacob, A.-C. Blumstein, Daniel Bur, Alain Chambovey, Lars Prade, Peter Seiler, Philippe Panchaud, Eric A. Ertel, Thierry Bruyère
Publikováno v:
Journal of Medicinal Chemistry. 60:3755-3775
Our strategy to combat resistant bacteria consisted of targeting the GyrB/ParE ATP-binding sites located on bacterial DNA gyrase and topoisomerase IV and not utilized by marketed antibiotics. Screening around the minimal ethyl urea binding motif led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd48a433f27169780b7c54901c1e1ae
https://doi.org/10.1021/acs.jmedchem.6b01834
https://doi.org/10.1021/acs.jmedchem.6b01834
Autor:
S Wiel, C Blumstein
Publikováno v:
Utilities Policy. 7:191-199
An unintended consequence of the restructuring of the electricity industry in the US has been a sharp decline in expenditures for research and development (R&D) by investor-owned utilities. This paper examines how the public interest may be damaged b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488345ef6ce728e3fdec17d4dc84beb8
https://doi.org/10.1016/s0957-1787(98)00014-9
https://doi.org/10.1016/s0957-1787(98)00014-9
Autor:
Ghenu, Maria Iuliana1,2 (AUTHOR) maria.ghenu@drd.umfcd.ro, Dragoș, Dorin1,2 (AUTHOR) dorin.dragos@umfcd.ro, Manea, Maria Mirabela3,4 (AUTHOR) maria.manea@umfcd.ro, Balcangiu-Stroescu, Andra-Elena5 (AUTHOR) andra.balcangiu@umfcd.ro, Ionescu, Dorin1,6 (AUTHOR), Negreanu, Lucian7,8 (AUTHOR) lucian.negreanu@umfcd.ro, Vlad, Adelina9 (AUTHOR) adelina.vlad@umfcd.ro
Publikováno v:
Diagnostics (2075-4418). Aug2024, Vol. 14 Issue 16, p1706. 18p.
Autor:
Mikula, Peter1,2,3 (AUTHOR) petomikula158@gmail.com, Bulla, Martin3 (AUTHOR) bulla.mar@gmail.com, Blumstein, Daniel T.4 (AUTHOR), Benedetti, Yanina3 (AUTHOR), Floigl, Kristina3 (AUTHOR), Jokimäki, Jukka5 (AUTHOR), Kaisanlahti-Jokimäki, Marja-Liisa5 (AUTHOR), Markó, Gábor6 (AUTHOR), Morelli, Federico3,7 (AUTHOR), Møller, Anders Pape8,9 (AUTHOR), Siretckaia, Anastasiia3 (AUTHOR), Szakony, Sára10 (AUTHOR), Weston, Michael A.11 (AUTHOR), Zeid, Farah Abou3 (AUTHOR), Tryjanowski, Piotr1,2,12 (AUTHOR), Albrecht, Tomáš13,14 (AUTHOR) albrecht@ivb.cz
Publikováno v:
Communications Biology. 7/17/2024, Vol. 7 Issue 1, p1-13. 13p.
Publikováno v:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1130f037661a932a913407802c96e9db
https://doi.org/10.1055/s-2005-867537
https://doi.org/10.1055/s-2005-867537
Publikováno v:
An-Najah University Journal for Research, B: Humanities. May2024, Vol. 38 Issue 5, p837-866. 30p.
Autor:
Kossieris, Stylianos1 (AUTHOR) stelios.kossieris@iccs.gr, Tsiakos, Valantis1 (AUTHOR), Tsimiklis, Georgios1 (AUTHOR), Amditis, Angelos1 (AUTHOR)
Publikováno v:
Remote Sensing. Apr2024, Vol. 16 Issue 7, p1181. 37p.