Zobrazeno 1 - 10
of 37
pro vyhledávání: '"C. Benckhuijsen"'
Publikováno v:
Progress in Regional Cancer Therapy ISBN: 9783642748202
Regional isolation perfusion of the limbs is now becoming a standard procedure worldwide. Its advantage is that a high dose of cytostatic drug can be administered to an isolated tumor-bearing region, localizing and enhancing the therapeutic effect wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932c3df30e46381057a6173bd7c8245f
https://doi.org/10.1007/978-3-642-74818-9_32
https://doi.org/10.1007/978-3-642-74818-9_32
Publikováno v:
Melanoma Research. 3:95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bba08b4d2f060a8670f3749f568ce7a
https://doi.org/10.1097/00008390-199303000-00358
https://doi.org/10.1097/00008390-199303000-00358
Publikováno v:
Cancer Letters. 18:283-289
Glutathione peroxidase activity in whole blood and selenium levels in whole blood and plasma from breast cancer patients, were measured during combination chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil. No significant change in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a076b878e49d33e03ec2cde6d5e4d07
https://doi.org/10.1016/0304-3835(83)90237-9
https://doi.org/10.1016/0304-3835(83)90237-9
Autor:
C. Benckhuijsen
Publikováno v:
Biochemical Pharmacology. 17:55-64
The behaviour of triethyleneimine thiophosphoramide (thio-TEPA) in acid medium has been studied. Evidence is presented of an intramolecular alkylation of the sulfur on protonation of the molecule. The five-membered ring formed in this way is hydrolyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d2d077dbb8c608d37d0c5f2327ebe5
https://doi.org/10.1016/0006-2952(68)90157-3
https://doi.org/10.1016/0006-2952(68)90157-3
Publikováno v:
Cancer research. 47(15)
The activity of beta-glucuronidase in methyl-N-nitrosourea-induced rat mammary tumors regressing after ovariectomy was studied. beta-Glucuronidase, acid phosphatase, and beta-hexosaminidase were similarly increased in the lysosome-rich fraction of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce0cc11f63a3a38ba6819f89ec091086
https://pubmed.ncbi.nlm.nih.gov/3607744
https://pubmed.ncbi.nlm.nih.gov/3607744
Publikováno v:
Cancer. 64(3)
From 1975 to 1986, 26 patients with soft tissue tumors of the extremities underwent a total of 29 perfusions. The cytostatics used were doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH) (19 perfusions), melphalan (two perfusions), and a comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a276d5f3972dfa8c958620dacd6a4e06
https://pubmed.ncbi.nlm.nih.gov/2743257
https://pubmed.ncbi.nlm.nih.gov/2743257
Publikováno v:
Cancer research. 47(18)
Three human melanoma cell lines of known content of specific glucocorticoid-binding sites were studied for colony formation after a microM dose of glucocorticoid combined with melphalan. In one of the three cell lines, M-5A, subcloned from M-5 (forme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b182288feb5cacdf7c57a371b24a32b
https://pubmed.ncbi.nlm.nih.gov/3621177
https://pubmed.ncbi.nlm.nih.gov/3621177
Publikováno v:
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 14(2)
The time course of tissue levels of melphalan during normothermic isolated limb perfusion, and the overall tissue levels per 60 min of perfusion, were estimated from the known pharmacokinetic parameters for a fixed dose of drug per liter of tissue (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69bd917721e4679bf9f4a2b040e2f8ba
https://pubmed.ncbi.nlm.nih.gov/3360157
https://pubmed.ncbi.nlm.nih.gov/3360157
Publikováno v:
Journal of cellular physiology. 125(2)
Proliferation of six established human melanoma cell lines was inhibited after treatment for 1 h with a high dose of glucocorticoid. Four of the lines with the capacity of colony formation were used to quantify final plating efficiency. Specific gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b487fabc5aa198bce596d8ddb36698d6
https://pubmed.ncbi.nlm.nih.gov/4055915
https://pubmed.ncbi.nlm.nih.gov/4055915
Publikováno v:
Anticancer research. 7(3 Pt)
Eighteen patients with advanced melanoma of the limbs underwent a single isolation perfusion with melphalan under normothermic conditions, i.e. tissue temperatures between 37.0 and 38.0 degrees C. There were no major complications. In 7 patients comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92c849d8718042859c2951bac18f7927
https://pubmed.ncbi.nlm.nih.gov/3631900
https://pubmed.ncbi.nlm.nih.gov/3631900