Zobrazeno 1 - 10
of 68
pro vyhledávání: '"C. Becherucci"'
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 2, Pp 103-107 (1993)
Peptide 204–212 of lipocortin (LC) 5 inhibited porcine pancreatic phospholipase A2 (PLA2) induced rat stomach strip contractions and ADP induced rabbit platelet aggregation in a concentration dependent manner (IC30 of 10 μM and 400 μM, respective
Externí odkaz:
https://doaj.org/article/6170fdb3e2874c9baba41dd5cb24eaf7
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 2, Pp 109-113 (1993)
Human recombinant lipocortins (LCT) 1 and 5 have been expressed in a yeast secretion vector and purified by ion exchange chromatography. The action of the proteins has been investigated in two models of experimental acute inflammation in the rat: car
Externí odkaz:
https://doaj.org/article/36263cd8e75942c59ca82c1621cd7fcd
Publikováno v:
British Journal of Pharmacology. 112:449-452
1. This study investigates the role of extracellular brain calcium in the hyperthermia induced by interleukin-1 beta (IL-1 beta). 2. Intracerebroventricular (i.c.v.) injection of IL-1 beta (12.5 ng kg-1) in rabbits caused a prompt and sustained rise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5268ee08494cc51540b91521b6fe9a0
https://doi.org/10.1111/j.1476-5381.1994.tb13093.x
https://doi.org/10.1111/j.1476-5381.1994.tb13093.x
Publikováno v:
Pharmacological Research. 29:367-372
A series of 4,5-functionalized 3(2H)-pyridazinones were evaluated as prostaglandin E2 (PGE2) and interleukin-1 (IL-1) release inhibitors from mouse adherent macrophages. Among the tested compounds only 2b was found to be devoid of activity in both th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bc10df6c683671e6860b94cd8fb443
https://doi.org/10.1016/1043-6618(94)80058-8
https://doi.org/10.1016/1043-6618(94)80058-8
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 2, Pp 103-107 (1993)
Mediators of Inflammation, Vol 2, Iss 2, Pp 103-107 (1993)
Peptide 204–212 of lipocortin (LC) 5 inhibited porcine pancreatic phospholipase A2(PLA2) induced rat stomach strip contractions and ADP induced rabbit platelet aggregation in a concentration dependent manner (IC30of 10 μM and 400 μM, respectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201f754960bb2327ba4a4399c290d6ac
https://doi.org/10.1155/s0962935193000146
https://doi.org/10.1155/s0962935193000146
Autor:
Giacomo Pozzoli, Ashley B. Grossman, Paolo Preziosi, C. Becherucci, Luca Parente, Pierluigi Navarra
Publikováno v:
Neuroendocrinology. 57:257-261
While interleukin-1 (IL-1) is intimately involved in locally modulating the acute inflammatory response, it is also able to influence processes at remote sites, i.e., in an endocrine manner. While the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a17ed12e2f1e6b5198a90aac8c30aff
https://doi.org/10.1159/000126367
https://doi.org/10.1159/000126367
Autor:
M. G. Longobardi, G. C. Viscomi, Mauro Perretti, S. Peppoloni, A. S. Verdini, S. Silvestri, M. Pinori, C. Becherucci, Luca Parente, P. Pileri
Publikováno v:
Journal of Medicinal Chemistry. 34:3372-3379
The tuftsin retro-inverso analogue H-Thr psi[NHCO](R,S)Lys-Pro-Arg-OH was synthesized through a novel procedure for the high-yield incorporation of isolated retro-inverso bonds into peptide chains and the use of the new Meldrum's acid derivative (CH3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19554ea52cf1b2791c4bfb8d0232e9b
https://doi.org/10.1021/jm00116a005
https://doi.org/10.1021/jm00116a005
Autor:
Gian Pietro Sgaragli, C. Becherucci, Mitri Palmi, Luca Parente, Maria Frosini, Mauro Perretti
Publikováno v:
European journal of pharmacology. 281(1)
The intracerebroventricular administration of interleukin-1 beta (12.5 ng/kg) in rabbits caused a prompt rise of prostaglandin E2 concentration (+ 632.6 +/- 243.9%) in the cerebrospinal fluid followed by hyperthermia (+ 1.61 +/- 0.14 delta degrees C)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac40bb086d7f56fbc4c56e35063269a
https://pubmed.ncbi.nlm.nih.gov/8566125
https://pubmed.ncbi.nlm.nih.gov/8566125
Publikováno v:
Neuroendocrinology. 57(2)
While interleukin-1 (IL-1) is intimately involved in locally modulating the acute inflammatory response, it is also able to influence processes at remote sites, i.e., in an endocrine manner. While there is as yet little evidence that IL-1 can cross t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd5ef151e0b97c13e5b57149bdfef8a2
https://pubmed.ncbi.nlm.nih.gov/8510801
https://pubmed.ncbi.nlm.nih.gov/8510801
Publikováno v:
Agents and actions.
Tuftsin, an immunostimulating tetrapeptide derived from immunoglobulin heavy chain, and its retro-inverso analogue have been tested in rat adjuvant arthritis. The secondary lesion of rats injected with Freund's adjuvant was significantly inhibited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd1ff07eb2ec66d8c8242c6776fabc23
https://pubmed.ncbi.nlm.nih.gov/1442329
https://pubmed.ncbi.nlm.nih.gov/1442329