Zobrazeno 1 - 10
of 80
pro vyhledávání: '"C. Babin-Chevaye"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:5018-5023
It is well acknowledged that ansamycins display immunosuppressive and anti-inflammatory properties in vitro and in vivo. Rifalazil, a new ansamycin derivative, has not been studied in the context of inflammation. In particular, there are no data on t
Publikováno v:
Journal of Chemotherapy. 17:385-392
Macrolides are accumulated in phagocytes, partially via an active transport system; the membrane carrier is not identified but many data indicate a link with the P-glycoprotein family which includes the Cystic Fibrosis Transmembrane Conductance Regul
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:2986-2989
We have studied the interference of roxithromycin with NADPH oxidase, the key enzymatic system for oxidant production by human neutrophils. Roxithromycin alters the reconstitution of an active enzyme and impairs the translocation to the outer membran
Publikováno v:
Journal of Chemotherapy. 15:350-356
Interactions between antibacterial agents and polymorphonuclear neutrophils (PMNs) are a major focus of investigation. Owing to the variable drug susceptibility of PMNs from different individuals, in vitro studies require samples from large panels of
Autor:
Catherine Pasquier, Fathi Driss, Michel De Bandt, M. Grossin, Joël Pincemail, C. Babin-Chevaye
Publikováno v:
Arthritis & Rheumatism. 46:522-532
Objective Reactive oxygen species are thought to play a role in rheumatoid arthritis (RA) in humans. We postulated that antioxidant treatment could have a beneficial effect in this disease. We therefore investigated the effects of vitamin E in the tr
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:S92-S95
Cultured human umbilical vein endothelial cells (HUVECs) treated with reactive oxygen species (ROS) show increased adherence of polymorphonuclear leukocytes (PMNs). Because pentoxifylline (PTX) is known to inhibit cell interactions, we studied PMN ad
Autor:
N. Amit, Jacques Hakim, C. Babin-Chevaye, Catherine Pasquier, Trung Pham Huu, M Amar, Jean-Yves Scoazec
Publikováno v:
Blood. 80:1546-1552
We have previously reported that K562, a chronic myelogenous leukemia cell line, releases a low molecular weight factor (6 to 8 Kd) that inhibits human polymorphonuclear neutrophil (PMN) adherence and adherence-related functions tested in vitro. We n
Publikováno v:
Antimicrobial agents and chemotherapy. 48(4)
A classical velocity centrifugation technique was used to study the in vitro uptake of the new ketolide ABT-773 by human polymorphonuclear neutrophils (PMNs) and a myelomonoblastic cell line, PLB-985, which can be differentiated into PMNs under certa
Publikováno v:
Journal of chemotherapy (Florence, Italy). 14(2)
Macrolide antibiotics have recently triggered much interest owing to the immunomodulatory potential of some derivatives, particularly in the field of inflammatory diseases. Among the possible mechanisms underlying these anti-inflammatory effects, mac
Autor:
Fathi Driss, M. Grossin, J Pincemail, C Gaertner, C. Babin-Chevaye, Catherine Pasquier, M. De Bandt
Publikováno v:
Speaker abstracts 2001.
Background Reactive oxygen species (ROS) are suspected to play a role in human RA. Transient hypoxia and ischaemic-reperfusion phenomenon are involved in their chronic production, by monocytes and macrophages. Nevertheless the clinical interest of RO