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Autor:
Daniel A. Nichols, J. A. Vigilante, Jeffrey Capers, J. R. Dettmer, Apurba K. Bhattacharjee, J. V. Vo, Clare E. Gutteridge, Lucia Gerena, S. L. Patterson, Karl A. Werbovetz, C. B. Tillett
Publikováno v:
Medicinal Chemistry. 3:115-119
The antileishmanial and antimalarial activity of methoxy-substituted chalcones (1,3-diphenyl-2-propen-1-ones) is well established. The few analogs prepared to date where the 3-phenyl group is replaced by either a pyridine or naphthalene suggest these