Zobrazeno 1 - 10
of 38
pro vyhledávání: '"C. B. Begg"'
Autor:
Serigne Lo, Jonathan M. Smith, Caro-Anne Badcock, Marianne Berwick, Lauren E. Haydu, Anne Kricker, Siok Leong, Yang Shi, C. B. Begg, Irene Orlow, P.A. Kanetsky, Nancy E. Thomas, Ajay Sharma, Anne E. Cust, Matthew Law, David W. Ollila, Sarah Yoo, John F. Thompson, Bruce K. Armstrong
Publikováno v:
The British journal of dermatology. 182(5)
Background Guidelines for follow-up of patients with melanoma are based on limited evidence. Objectives To guide skin surveillance, we developed a risk prediction model for subsequent primary melanomas, using demographic, phenotypical, histopathologi
Publikováno v:
Statistics in medicine. 19(15)
We consider the problem of comparing alternative cancer staging and grading systems. Statistical comparisons are on the basis of the ability to predict survival, but more qualitative criteria, such as parsimony, and distinctive prognostic separabilit
Publikováno v:
AJR. American journal of roentgenology. 169(2)
Patients with nonseminomatous germ cell cancer of the testis with no evidence of metastatic disease after orchiectomy may be managed with either retroperitoneal lymph node dissection or surveillance. The present retrospective study was undertaken to
Publikováno v:
Urology. 49(4A)
To address principles in the design and conduct of clinical trials on prostate cancer (PC) with special reference to localized disease.In advance of and during the World Health Organization (WHO) conference on Prostate Cancer in Stockholm in Septembe
Autor:
C B, Begg, M, Berwick
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 6(2)
The comparison of an incident case series with an incident series of second primary cancers, using either a case-control or follow-up study design, is proposed as an efficient method for evaluating the relative risk of a rare genetic susceptibility m
Publikováno v:
Biometrics. 52(3)
A new approach is presented for determining the appropriate sample sizes for a series of screening trials to identify promising new therapeutic agents. The formulation of the problem is motivated by recognition of the fact that screening of new agent
Autor:
C B, Begg
Publikováno v:
Statistics in medicine. 15(12)
The randomized clinical trial is the gold standard methodology for evaluating treatment interventions. The randomized trial is a prospective experimental study, the embodiment of the scientific method applied to the clinic. Both organizational and et
Autor:
C B, Begg
Publikováno v:
Seminars in oncology. 21(5)
Clinical and epidemiological research on prostate cancer is faced with some unusual methodological challenges. The very high prevalence of latent cancer, much of which never becomes clinically manifest, complicates the approach to screening and the c
Autor:
C B, Begg, Z F, Zhang
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 3(2)
The case-series design is being used increasingly to explore associations between environmental risk factors and genetic markers. It is demonstrated that the odds ratio derived from a case-series study is the ratio of the relative risk for developing
Publikováno v:
Biometrics. 47(3)
A method is presented for estimating the treatment effect in a meta-analysis when some of the studies are comparative studies, and the rest are noncomparative, historical control studies. A random-effects model is used in which the baseline effect in