Zobrazeno 1 - 10
of 271
pro vyhledávání: '"C. Astre"'
Autor:
Frédéric Pinguet, Isabelle Solassol, Françoise Bressolle, V. Charasson, C. Astre, L. Philibert
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 29:2957-2974
The aim of this paper was to develop a specific and sensitive liquid chromatography/electrospray ionization mass spectrometry method for the determination of imatinib and its metabolite in human plasma. The method involved a solid phase extraction of
Autor:
Michel Fabbro, Frédéric Pinguet, S. Poujol, P. Mougenot, Françoise Bressolle, C. Astre, S. Culine, F. Malosse
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 27:301-313
A high‐performance liquid chromatographic (HPLC) method for the determination of melphalan in human plasma was developed. This method involved a solid phase extraction (SPE) of melphalan and the internal standard (propylparaben) from plasma, using
Autor:
C. Astre, Stéphane Culine, Françoise Malosse, Marc Ychou, Françoise Bressolle, Sylvain Poujol, Frédéric Pinguet
Publikováno v:
Clinical Chemistry. 49:1900-1908
Background: We developed gradient HPLC methods for quantification of the antimitotic drug irinotecan (CPT-11) and its four metabolites, SN-38, SN-38 G, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]-carbonyloxycamptothecin (APC), and 7-ethyl-1
Autor:
Roberto Gomeni, Frédéric Pinguet, Amélie Gauvin, C. Astre, Stéphane Culine, Françoise Bressolle
Publikováno v:
Anti-Cancer Drugs. 13:473-480
The aim of this study was to characterize the population pharmacokinetic of vinorelbine In elderly patients and to propose a limited-sampling strategy to estimate individual pharmacokinetic parameters.Vinorelbine was administered by a 10 -min continu
Blood and plasma pharmacokinetics of vinorelbine in elderly patients with advanced metastatic cancer
Autor:
Amélie Gauvin, C. Astre, Françoise Bressolle, Stéphane Culine, Frédéric Pinguet, Didier Cupissol
Publikováno v:
Cancer Chemotherapy and Pharmacology. 49:48-56
Purpose: As vinorelbine is 78% bound to platelets, it seems interesting to investigate the pharmacokinetic profile of this drug from blood and to compare it to that determined from plasma. Thus, in this study, the comparative blood/plasma pharmacokin
Autor:
Frédéric Pinguet, F. Bressolle, C. Astre, S. Poujol, M. Boucaud, Stéphane Culine, Didier Cupissol, Gilles Romieu
Publikováno v:
European Journal of Cancer. 37:2357-2364
The comparative saliva/plasma pharmacokinetics of topotecan were investigated in 13 patients with metastatic epithelial ovarian cancer receiving topotecan (30-min intravenous (i.v.) infusion) on a five consecutive day schedule every 3 weeks. During t
Autor:
Mariette Gerber, M Durand, Jean Dallongeville, Jacqueline Scali, C. Astre, Monique Romon, Anne Michaud
Publikováno v:
Journal of the American Dietetic Association. 100:1164-1171
Objectives The failure of single-nutrient supplementation to prevent disease in intervention studies underlines the necessity to develop a holistic view of food intake. The objectives of this study were to devise a diet quality index (DQI) and identi