Zobrazeno 1 - 10
of 84
pro vyhledávání: '"C. Arteaga de Murphy"'
Autor:
Clara Santos-Cuevas, Ignacio A. Rivero, Rocío García-Becerra, Blanca Ocampo-García, J. I. Sarmiento, David Ordaz-Rosado, C. Arteaga de Murphy, Guillermina Ferro-Flores
Publikováno v:
Applied Radiation and Isotopes. 68:2274-2278
99m Tc-HYNIC labeled Lys 3 -bombesin has shown specific binding to gastrin-releasing peptide receptors (GRP-r) over-expressed in cancer cells. Click chemistry offers an innovative functionalization strategy for biomolecules such as bombesin. The aim
Autor:
Guillermina Ferro-Flores, C. Arteaga de Murphy, M.-A. T. Ramírez-Iglesias, J. Rodríguez-Cortés, Martha Pedraza-López
Publikováno v:
Radiation Effects and Defects in Solids. 162:797-801
Radiolabelled peptides have been used as target-specific radiopharmaceuticals. The goal of this research was the in vitro assessment of the uptake, internalization, externalization, and efflux of five radiolabelled peptides in cancer cells to estimat
Autor:
J. Rodríguez-Cortés, C. Arteaga de Murphy, Martha Pedraza-López, Eduardo Murphy-Stack, Ge Ferro-Flores
Publikováno v:
Radiation Effects and Defects in Solids. 162:791-796
Malignant pancreatic tumours induced in athymic mice are a good model for peptide receptor targeted radiotherapy. The objective of this research was to determine biokinetic parameters in mice, in order to estimate the induced pancreatic tumour absorb
Autor:
P. Palomares-Rodríguez, Laura Meléndez-Alafort, Martha Pedraza-López, Guillermina Ferro-Flores, C. Arteaga de Murphy
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 266:307-311
The ubiquicidin 29-41 fragment (UBI) is a cationic antimicrobial peptide. The aim of this study was to develop an instant kit formulation for the preparation of 99mTc-UBI 29-41 in high radiochemical yield and to evaluate its use as an infection imagi
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 260:477-489
Good manufacturing practices specify that a well-type scintillation NaI(Tl) crystal detector has to be validated in order to detect radioactivity from any radiopharmaceutical used to obtain radiopharmacokinetic parameters. A 5 cm well-type NaI(Tl) sc
Autor:
F. Monroy-Guzmán, Guillermina Ferro-Flores, Martha Pedraza-López, C. Arteaga de Murphy, Laura Meléndez-Alafort, J. I. Tendilla, R Jiménez-Varela
Publikováno v:
International Journal of Pharmaceutics. 255:129-138
The aim of this work was to synthesize [ 166 Dy ] Dy / 166 Ho -DTPA-Biotin to evaluate its potential as a new radiopharmaceutical for targeted radiotherapy. Dysprosium-166 ( 166 Dy ) was obtained by neutron irradiation of enriched 164 Dy 2 O 3 in a T
Autor:
Eva María Molina-Trinidad, C. Arteaga de Murphy, Martha Pedraza-López, O Villanueva-Sanchez, Laura Meléndez-Alafort, Eduardo Murphy-Stack, Guillermina Ferro-Flores
Publikováno v:
International Journal of Pharmaceutics. 233:29-34
Infarct-avid radiopharmaceuticals are necessary for rapid and timely diagnosis of acute myocardial infarction. The animal model used to produce infarction implies artery ligation but chemical induction can be easily obtained with isoproterenol. A new
Autor:
L. García-Salinas, Guillermina Ferro-Flores, F. de M. Ramírez, Martha Pedraza-López, M.G. Martínez-mendoza, C. Arteaga de Murphy
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 251:7-13
Lanreotide peptide was labeled with 153Sm-H1ETA and 188Re-MAG3 in order to evaluate whether or not their conjugation to the peptide produce significant differences of the in vitro lipophilicity with respect to the 188Re-lanreotide prepared by the dir
Autor:
C. Arteaga de Murphy, Martha Pedraza-López, V. Lopez-Rodriguez, R. E. Gaspar-Carcamo, Miguel A. Avila-Rodriguez, E.L. Rojas-Calderon, Guillermina Ferro-Flores
Publikováno v:
Nuclear medicine and biology. 42(2)
Introduction Integrin α v β 3 plays an important role in angiogenesis and is over-expressed in tumoral endothelial cells and some other tumor cells. RGD (Arg-Gly-Asn) peptides labeled with 68 Ga (t 1/2 =68min) have showed good characteristics for i
Autor:
C. Arteaga de Murphy, E. Gómez, O. Martínez-Rivero, Laura Meléndez-Alafort, Guillermina Ferro-Flores
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 220:41-45
A new technetium labeling method for immunoglobulin reduced with tris(2-carboxy-ethyl)phosphine hydrochloride is presented. The Sandoglobulina IgG source was assayed for purity and optimum reagent's concentration and incubation times were determined.