Výsledky vyhledávání - "C. Andrew Powers"

Comparison of Tamoxifen and Testosterone Propionate in Male Rats: Differential Prevention of Orchidectomy Effects on Sex Organs, Bone Mass, Growth, and the Growth Hormone-IGF-I Axis

Autor: C. Andrew Powers, James M. Fitts, Robert M. Klein

Publikováno v: Journal of Andrology. 25:523-534

Testis dysfunction can weaken bone and reduce muscle mass as well as impair sexual function. Testosterone (T) therapy has useful effects on sex organs, bone, and muscle in T-deficient males, but prostate concerns can preclude T use in some men. Altho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686750be7e89de1e55d90736d66605a
https://doi.org/10.1002/j.1939-4640.2004.tb02823.x

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Estrogen and Tamoxifen Interplay with T3 in Male Rats: Pharmacologically Distinct Classes of Estrogen Responses Affecting Growth, Bone, and Lipid Metabolism, and Their Relation to Serum GH and IGF-I

Autor: C. Andrew Powers, Robert M. Klein, James M. Fitts

Publikováno v: Endocrinology. 142:4223-4235

Estrogen (E) and T(3) regulate gene expression by receptor mechanisms that may enable hormonal interplay affecting growth and metabolism. Prior studies of E and tamoxifen (TM) interplay with T(3) in female rats identified a subset of E responses that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9304389a2d06f484d1bcf0eb43a80df
https://doi.org/10.1210/endo.142.10.8445

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Tamoxifen regulation of bone growth and endocrine function in the ovariectomized rat: discrimination of responses involving estrogen receptor α/estrogen receptor β, G protein-coupled estrogen receptor, or estrogen-related receptor γ using fulvestrant (ICI 182780)

Autor: James M. Fitts, C. Andrew Powers, Robert M. Klein

Publikováno v: The Journal of pharmacology and experimental therapeutics. 338(1)

Tamoxifen is a selective estrogen receptor (ER) modulator, but it is also a deactivating ligand for estrogen-related receptor-γ (ERRγ) and a full agonist for the G protein-coupled estrogen receptor (GPER). Fulvestrant is a selective ER down-regulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8897053145d059af4f24c065ab5c31
https://pubmed.ncbi.nlm.nih.gov/21464335

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Male gender and not the severity of hypertension is associated with end-organ damage in aged stroke-prone spontaneously hypertensive rats

Autor: Charles T. Stier, C. Andrew Powers, Praveen N. Chander, Sreeharsha N. Masineni, Gagan D. Singh

Publikováno v: American journal of hypertension. 18(6)

It is well-known that gender affects the progression of kidney failure. Male patients exhibit faster development of age-dependent renal disease than do women. In the present study, we examined arterial blood pressure (BP), proteinuria, and end-organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df549a29a06332ce7520a81142c6738e
https://pubmed.ncbi.nlm.nih.gov/15925751

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Estrogen promotes microvascular pathology in female stroke-prone spontaneously hypertensive rats

Autor: C. Andrew Powers, Praveen N. Chander, Charles T. Stier, Louis Rosenfeld

Publikováno v: American journal of physiology. Endocrinology and metabolism. 285(1)

Estrogen produces both beneficial and adverse effects on cardiovascular health via mechanisms that remain unclear. Stroke-prone spontaneously hypertensive rats (SHRSP) maintained on Stroke-Prone Rodent Diet and 1% NaCl drinking water (starting at 8 w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8689ebf460760ea14df95b896a6afda
https://pubmed.ncbi.nlm.nih.gov/12670833

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A Kininogenase Resembling Glandular Kallikrein in the Rat Pituitary Pars Intermedia

Autor: Alberto Nasjletti, C. Andrew Powers

Publikováno v: Endocrinology. 112:1194-1200

The purpose of this study was to determine the distribution and characteristics of kinin-generating proteases (kininogenases) in rat pituitary tissue. Male rat pituitaries were dissected into their various lobes, sonicated in saline containing 12 mM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112bdb1416e9e95cfe0563579d07f80e
https://doi.org/10.1210/endo-112-4-1194

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Reduced glandular kallikrein-like activity in the anterior pituitary of the new zealand genetically hypertensive rat

Autor: Philip G. Baer, C. Andrew Powers, Alberto Nasjletti

Publikováno v: Biochemical and Biophysical Research Communications. 119:689-693

Summary Anterior pituitaries of New Zealand genetically hypertensive and normotensive rats were compared for their content of glandular kallikrein-like activity. Anterior pituitary homogenates were assayed for their ability to cleave a chromogenic pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76b4c55edb3441fc86d25bf4814a39
https://doi.org/10.1016/s0006-291x(84)80305-8

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Anterior pituitary glandular kallikrein: Trypsin activation and estrogen regulation

Autor: C. Andrew Powers

Publikováno v: Molecular and Cellular Endocrinology. 46:163-174

Discrepant reports exist regarding the presence of glandular kallikrein or other trypsin-like serine proteases in the pituitary. The existence of pituitary kallikreins in latent forms could explain these discrepancies. I report that trypsin treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1088edab0e0071735566f88db5135d4
https://doi.org/10.1016/0303-7207(86)90095-x

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