Zobrazeno 1 - 10
of 37
pro vyhledávání: '"C. Andrew Frank"'
Autor:
Noah S. Armstrong, C. Andrew Frank
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
Introduction: The ability of synapses to maintain physiological levels of evoked neurotransmission is essential for neuronal stability. A variety of perturbations can disrupt neurotransmission, but synapses often compensate for disruptions and work t
Externí odkaz:
https://doaj.org/article/e1d57c35801748c682787d854ae44c39
Autor:
Bhagaban Mallik, C. Andrew Frank
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
To identify conserved components of synapse function that are also associated with human diseases, we conducted a genetic screen. We used the Drosophila melanogaster neuromuscular junction (NMJ) as a model. We employed RNA interference (RNAi) on sele
Externí odkaz:
https://doaj.org/article/dbf1c0352b1a4c2498384f262f2a702f
Autor:
Catherine J. Yeates, C. Andrew Frank
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Synapses and circuits rely on homeostatic forms of regulation in order to transmit meaningful information. The Drosophila melanogaster neuromuscular junction (NMJ) is a well-studied synapse that shows robust homeostatic control of function. Most prio
Externí odkaz:
https://doaj.org/article/7211046b49a546e3b9365c6636b093ee
Publikováno v:
eLife, Vol 8 (2019)
Synapses and circuits rely on neuroplasticity to adjust output and meet physiological needs. Forms of homeostatic synaptic plasticity impart stability at synapses by countering destabilizing perturbations. The Drosophila melanogaster larval neuromusc
Externí odkaz:
https://doaj.org/article/4f9549e113b54a0385f95ecd90f03291
Autor:
Douglas J Brusich, Ashlyn M Spring, Thomas D James, Catherine J Yeates, Timothy H Helms, C Andrew Frank
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://doaj.org/article/8e84afdcc7674cc9a7d61507fc3ce816
Autor:
C. Andrew Frank, Noah Armstrong
The ability of synapses to maintain physiological levels of evoked neurotransmission is essential for neuronal stability. A variety of perturbations can disrupt neurotransmission, but synapses often compensate for disruptions and work to stabilize ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21016cdb81eb4a70a0e03c1f51ebd4d0
https://doi.org/10.1101/2022.08.31.506100
https://doi.org/10.1101/2022.08.31.506100
Autor:
Qiuling Li, David A Kellner, Hayden A M Hatch, Tomohiro Yumita, Sandrine Sanchez, Robert P Machold, C Andrew Frank, Nicholas Stavropoulos
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006815 (2017)
Sleep is an ancient animal behavior that is regulated similarly in species ranging from flies to humans. Various genes that regulate sleep have been identified in invertebrates, but whether the functions of these genes are conserved in mammals remain
Externí odkaz:
https://doaj.org/article/62c8ebf23cb44964b955c2cdac45e08b
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005886 (2016)
Forms of homeostatic plasticity stabilize neuronal outputs and promote physiologically favorable synapse function. A well-studied homeostatic system operates at the Drosophila melanogaster larval neuromuscular junction (NMJ). At the NMJ, impairment o
Externí odkaz:
https://doaj.org/article/81e0230539fd4423b895b36ce8a1600e
Autor:
BHAGABAN MALLIK, C. Andrew Frank
Publikováno v:
Frontiers in neuroscience. 16
To identify conserved components of synapse function that are also associated with human diseases, we conducted a genetic screen. We used the Drosophila melanogaster neuromuscular junction (NMJ) as a model. We employed RNA interference (RNAi) on sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8de634f7b8333d2843ddc48ed0aae3
https://pubmed.ncbi.nlm.nih.gov/35557603
https://pubmed.ncbi.nlm.nih.gov/35557603