Výsledky vyhledávání - "C. Alyson Evans"

Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone

Autor: C. Alyson Evans, Julia K L Woodward, Diane V. Lefley, Penelope D. Ottewell, Ingunn Holen, Robert E. Coleman

Publikováno v: Molecular Cancer Therapeutics. 8:2821-2832

Patients with advanced breast cancer frequently develop bone metastases, and at this stage, the disease is considered incurable. Here, we show that a 6-week course of weekly administration of doxorubicin (2 mg/kg), followed 24 hours later by the bisp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3050f7b0be7c2dba546e91657753fa
https://doi.org/10.1158/1535-7163.mct-09-0462

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Different molecular profiles are associated with breast cancer cell homing compared with colonisation of bone: evidence using a novel bone-seeking cell line

Autor: Penelope D. Ottewell, Matthew Walker, Hannah K Brown, Ingunn Holen, Robert E. Coleman, Simon S. Cross, C. Alyson Evans, Peter Selby, Faith Nutter, Jules A. Westbrook, Janet E. Brown

Publikováno v: Endocrine-related cancer. 21(2)

Advanced breast cancer is associated with the development of incurable bone metastasis. The two key processes involved, tumour cell homing to and subsequent colonisation of bone, remain to be clearly defined. Genetic studies have indicated that diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277d4ed2f5a36e3617a6f44f334283da
https://pubmed.ncbi.nlm.nih.gov/24413608

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Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model

Autor: Simon S. Cross, C. Alyson Evans, Diane V. Lefley, Penelope D. Ottewell, Ingunn Holen, Robert E. Coleman

Publikováno v: International journal of cancer. 126(2)

Combination therapy, using agents that target the microenvironment as well as the cancer cells, is common in the treatment of advanced breast cancer. Here, we show that a 6-week course of weekly sequential administration of the cytotoxic drug doxorub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61babb4d0c17bb9836ab7f54b034d639
https://pubmed.ncbi.nlm.nih.gov/19621384

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Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival?

Autor: Simon S. Cross, H.L. Neville-Webbe, Neil Cross, Sabapathy P. Balasubramanian, Robert E. Coleman, Peter I. Croucher, Colby L. Eaton, J M Lippitt, C. Alyson Evans, Ingunn Holen

Publikováno v: Breast cancer research and treatment. 92(3)

In addition to its role in bone turnover, osteoprotegerin (OPG) has been reported to bind to and inhibit Tumour necrosis factor-related apoptosis inducing ligand (TRAIL). TRAIL is produced in tumours by invading monocytes, inducing apoptosis in neopl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb15a1c985f2617f21b66c235ae6fd5
https://pubmed.ncbi.nlm.nih.gov/16155791

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Akademický článek

Osteoprotegerin (OPG) Expression by Breast Cancer Cells in vitro and Breast Tumours in vivo – A Role in Tumour Cell Survival?

Autor: Ingunn Holen, Simon S. Cross, Helen L. Neville-Webbe, Neil A. Cross, Sabapathy P. Balasubramanian, Peter I. Croucher, C. Alyson Evans, Jennifer M. Lippitt, Robert E. Coleman, Colby L. Eaton

Publikováno v: Breast Cancer Research & Treatment; Aug2005, Vol. 92 Issue 3, p207-215, 9p

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Akademický článek

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