Persistent inflammation and endothelial dysfunction in patients with treated acromegaly

Autor: T L C Wolters, C D C C van der Heijden, N van Leeuwen, B T P Hijmans-Kersten, M G Netea, J W A Smit, D H J Thijssen, A R M M Hermus, N P Riksen, R T Netea-Maier

Publikováno v: Endocrine Connections, Vol 8, Iss 12, Pp 1553-1567 (2019)

Objective: Acromegaly is characterized by an excess of growth hormone (GH) and insulin-like growth factor 1 (IGF1). Cardiovascular disease (CVD) risk factors are common in acromegaly and often persist after treatment. Both acute and long-lasting pro-

Externí odkaz: https://doaj.org/article/cee77be78a1f49389b248fc341f78de2

Expediting the Implementation of Closed-Loop Supply Chain Management: a Facilitated Case Study on Re-using Timber in Construction Projects

Autor: Jannie Coenen, Rob E. C. M. van der Heijden, Allard C. R. van Riel

Publikováno v: Circular Economy and Sustainability, 1

An increasing number of firms are aiming to implement closed-loop supply chain (CLSC) management to contribute to a more circular economy. However, for many of these firms, it is difficult to translate this strategic aim into fruitful operational dec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491528187db0933fd4ae12d5ed6b5a09
https://doi.org/10.1007/s43615-022-00186-6

Two week interruption of statin therapy results in an exaggerated inflammatory phenotype in young myocardial infarction patients without standard modifiable risk factors

Autor: J H Q Mol, J Van Tuijl, S Bekkering, C Stolk-Van Der Heijden, S Damen, B Cossins, L Van Emst, G Pop, M Netea, N Van Royen, N Riksen, S El Messaoudi

Publikováno v: European Heart Journal. 43

Background In patients with myocardial infarction (MI) it is recommended to start high intensity statin therapy, as early as possible, irrespective of lipid levels at presentation. In ST-elevated myocardial infarction (STEMI) patients that do not hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6a5a4e42420f6e621f7ffc7de0c22fd
https://doi.org/10.1093/eurheartj/ehac544.1286

An integrative genomics approach identifies KDM4 as a modulator of trained immunity

Autor: Boris Novakovic, Laszlo Groh, Vasiliki Matzaraki, Charlotte D C C van der Heijden, Jelmer H van Puffelen Heijden, Simone J.C.F.M. Moorlag, Marije Oosting, Cisca Wijmenga, Mihai G. Netea, Leo A. B. Joosten, Vinod Kumar, Sanne P. Smeekens, Niels P. Riksen, Samuel T. Keating, Yang Li, Valerie A. C. M. Koeken, Raúl Aguirre Gamboa, L. Charlotte J. de Bree, Olivier B. Bakker, Reinout van Crevel, Ramnik J. Xavier

Publikováno v: European Journal of Immunology, 52, 3, pp. 431-446
European Journal of Immunology, 52(3), 431-446. Wiley
Moorlag, S J C F M, Matzaraki, V, van Puffelen, J H, van der Heijden, C, Keating, S, Groh, L, Röring, R J, Bakker, O B, Koeken, V A C M, de Bree, L C J, Smeekens, S P, Oosting, M, Gamboa, R A, Riksen, N P, Xavier, R J, Wijmenga, C, Kumar, V, van Crevel, R, Novakovic, B, Joosten, L A B, Li, Y & Netea, M G 2022, ' An integrative genomics approach identifies KDM4 as a modulator of trained immunity ', European Journal of Immunology, vol. 52, no. 3, pp. 431-446 . https://doi.org/10.1002/eji.202149577
European Journal of Immunology, 52, 431-446
Eur J Immunol.

Contains fulltext : 248704.pdf (Publisher’s version ) (Open Access) Innate immune cells are able to build memory characteristics via a process termed "trained immunity." Host factors that influence the magnitude of the individual trained immunity r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebff8ae4b0d2d05bcc06c2f8363ea1b0
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/248704

Arterial Wall Inflammation and Increased Hematopoietic Activity in Patients With Primary Aldosteronism

Autor: Leo A. B. Joosten, Jaap Deinum, Alexander Hoischen, Charlotte D C C van der Heijden, Mihai G. Netea, Marlies P. Noz, Charlotte Kaffa, Esther M.M. Smeets, Simone Kersten, Erik H.J.G. Aarntzen, Houshang Monajemi, Niels P. Riksen

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 105, 5
Journal of Clinical Endocrinology and Metabolism, 105
The Journal of Clinical Endocrinology and Metabolism

Context Primary aldosteronism (PA) confers an increased risk of cardiovascular disease (CVD), independent of blood pressure. Animal models have shown that aldosterone accelerates atherosclerosis through proinflammatory changes in innate immune cells;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63c89ad2b6c093d5938603f99e3db88
https://doi.org/10.1210/clinem/dgz306