Zobrazeno 1 - 10
of 230
pro vyhledávání: '"C. A. Van Hasselt"'
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Zhongqin Gong, Shucai Yang, Minghui Wei, Alexander C. Vlantis, Jason Y. K. Chan, C. Andrew van Hasselt, Dongcai Li, Xianhai Zeng, Lingbin Xue, Michael C. F. Tong, George G. Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The incidence of thyroid cancer was predominant in women, indicating that the sex hormone may have a role in thyroid cancer development. Generally, the sex hormone exerts its function by binding to the correspondent nuclear receptors. Therefore, aber
Externí odkaz:
https://doaj.org/article/5bdcecf656f142669a720827f210e1d1
Autor:
Shucai Yang, Zhongqin Gong, Zhimin Liu, Minghui Wei, Lingbin Xue, Alexander C. Vlantis, Yang Zhang, Jason YK. Chan, C Andrew van Hasselt, Xianhai Zeng, Shuqi Qiu, Nelson Tang, Jing Du, Wei Wei, Michael CF Tong, George G. Chen
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
PurposeThe inhibition of estrogen receptor alpha (ERα) or the activation of ERβ can inhibit papillary thyroid cancer (PTC), but the precise mechanism is not known. We aimed to explore the role of ERα and ERβ on the production of endogenous peroxi
Externí odkaz:
https://doaj.org/article/ecae1b796bb14602b96cc0f5636698c4
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f4c5624de0d740c496d631d66856f4cf
Autor:
Willis S.S. Tsang, Michael C.F. Tong, Peter K.M. Ku, Kunwar S.S. Bhatia, Joannie K.Y. Yu, Terence K.C. Wong, C. Andrew van Hasselt
Publikováno v:
Journal of Otology, Vol 11, Iss 4, Pp 157-164 (2016)
Managing microtia patients is always a challenge. Multidisciplinary approach, good family support, well established doctor–patient relationship and well organised patient-support groups are the essential elements for success. With the advancement o
Externí odkaz:
https://doaj.org/article/3ec82f0f5fab40de87e12ef3206cc436
Autor:
Jason Y. K. Chan, Vivian Wai Yan Lui, Sau Dan Lee, Trevor J. Pugh, Brigette B.Y. Ma, Yvonne Y. Y. Or, Kwok Wai Lo, Lee Fah Yap, Yuk-Yu Chan, Edwin P. Hui, Fei-Fei Liu, Yuchen Liu, Michael K. F. Mak, Chit Chow, Pui Kei Siu, Anthony T.C. Chan, Samah El Ghamrasni, Chi Man Tsang, Grace Tin-Yun Chung, Johnny S. H. Kwan, Ian C. Paterson, Jeff Bruce, Man Wu, C. Andrew van Hasselt, Kevin Y. Yip, Christopher W. Dawson, Sai Wah Tsao, John K. S. Woo, Sharmila Velapasamy, Ka Fai To, Lawrence S. Young, Stephenie Prokopec
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Interplay between EBV infection and acquired genetic alterations during nasopharyngeal carcinoma (NPC) development remains vague. Here we report a comprehensive genomic analysis of 70 NPCs, combining whole-genome sequencing (WGS) of microdissected tu
Autor:
C. Andrew van Hasselt, Cheuk Lun Sham, Michael C. F. Tong, John K. S. Woo, Ryan H W Cho, Dennis L.Y. Lee, Samuel M W Chow
Publikováno v:
The Laryngoscope
Objectives/hypothesis This study analyzes the treatment outcomes of frontal inverted papillomas (FIPs) in an attempt to provide guidelines for surgery selection. Study design Retrospective case series. Methods The treatment results of 29 FIPs classif
Autor:
Jason Y. K. Chan, Yang Zhang, Lingbin Xue, Zhongqin Gong, C. Andrew van Hasselt, Michael Cf Tong, Minghui Wei, Xianhai Zeng, George G. Chen, Wei Wei, Nelson L.S. Tang, Shuqi Qiu, Shucai Yang, Alexander C. Vlantis, Jing Du, Zhi-Min Liu
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
PurposeThe inhibition of estrogen receptor alpha (ERα) or the activation of ERβ can inhibit papillary thyroid cancer (PTC), but the precise mechanism is not known. We aimed to explore the role of ERα and ERβ on the production of endogenous peroxi
Autor:
Jason Y. K. Chan, Xianhai Zeng, Alexander C. Vlantis, C. Andrew van Hasselt, Minghui Wei, George G. Chen, Dongcai Li, Zhi-Min Liu, Michael C. F. Tong, Zhongqin Gong, Lingbin Xue
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Papillary thyroid cancer can dedifferentiate into a much more aggressive form of thyroid cancer, namely into anaplastic thyroid cancer. Nrf2 is commonly activated in papillary thyroid cancer, whereas its role in anaplastic thyroid cancer has not been
Autor:
Michael Cf Tong, Jason Y. K. Chan, George G. Chen, Shaoming Zhou, Mo-Xian Chen, Shanshan Wang, Mingyue Li, Shuqi Qiu, Wei Guo, Yi Liu, C. Andrew van Hasselt, Lingbin Xue, Alexander C. Vlantis, Xianhai Zeng, Shucai Yang, Bao-guang Hu
Publikováno v:
Expert opinion on therapeutic targets. 24(9)
Cisplatin is a chemotherapy drug that has been used to treat a number of cancers for decades, and is still one of the most commonly used anti-cancer agents. However, some patients do not respond to cisplatin while other patients who were originally s