Výsledky vyhledávání - "C. A. Tregaskes"

Oxidative stress, activity behaviour and body mass in captive parrots

Autor: Stephen D. Larcombe, A. E. Stevenson, C. A. Tregaskes, J. S. Coffey, Lucille Alexander, Kathryn E. Arnold

Publikováno v: Conservation Physiology

Captive breeding programmes are common for many parrot species. We show that in small parrots kept in standard cages with ad libitum food, high weight gain was prevalent and linked with a risk of DNA damage. Such damage could explain the poor health,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bf23cfc993bd28d99211dc0df2b860
https://pubmed.ncbi.nlm.nih.gov/27293729

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Marek's disease is a natural model for lymphomas overexpressing Hodgkin's disease antigen (CD30)

Autor: C. A. Tregaskes, Mark S. Parcells, L. N. J. Ross, Lucy F. Lee, Lawrence G. Hunt, Shane C. Burgess, B. J. G. Baaten, T. F. Davison, Pradeep Kumar, John R. Young

Publikováno v: Proceedings of the National Academy of Sciences. 101:13879-13884

Animal models are essential for elucidating the molecular mechanisms of carcinogenesis. Hodgkin's and many diverse non-Hodgkin's lymphomas overexpress the Hodgkin's disease antigen CD30 (CD30hi), a tumor necrosis factor receptor II family member. Her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0c437b57b3a0e2b49757a8b1409343
https://doi.org/10.1073/pnas.0305789101

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Cloning and Modeling of the First Nonmammalian CD4

Autor: R, Koskinen, U, Lamminmäki, C A, Tregaskes, J, Salomonsen, J R, Young, O, Vainio

Publikováno v: The Journal of Immunology. 162:4115-4121

We have cloned and sequenced the first nonmammalian CD4 cDNA from the chicken using the COS cell expression method. Chicken CD4 contains four extracellular Ig domains that, in analogy to mammalian CD4, are in the order V, C2, V, and C2. The molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addc77c2a7ab18ba1206eb92faae3cef
https://doi.org/10.4049/jimmunol.162.7.4115

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The avian chB6 (Bu-1) alloantigen can mediate rapid cell death

Autor: P E Funk, C A Tregaskes, J R Young, C B Thompson

Publikováno v: The Journal of Immunology. 159:1695-1702

The control of cell death is critical in the immune system. T and B lymphocytes must be censored during their development to remove nonfunctional or self-reactive lymphocytes. However, the molecules controlling cell deletion during lymphopoiesis have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ff1243dac684c452a45de40f8336615
https://doi.org/10.4049/jimmunol.159.4.1695

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Identification of a novel class of mammalian Fc gamma receptor

Autor: G Zhang, J R Young, C A Tregaskes, P Sopp, C J Howard

Publikováno v: The Journal of Immunology. 155:1534-1541

A cDNA encoding an Ig receptor that conferred the ability to bind erythrocytes sensitized with IgG2, but not IgG1, was cloned by screening a cattle alveolar macrophage library, made in the vector pCDM8, expressed in COS-7 cells. A search of the PIR d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79e3a08bf9ad7a0679dbee19eafc1685
https://doi.org/10.4049/jimmunol.155.3.1534

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Identification and analysis of the expression of CD8 alpha beta and CD8 alpha alpha isoforms in chickens reveals a major TCR-gamma delta CD8 alpha beta subset of intestinal intraepithelial lymphocytes

Autor: C A Tregaskes, F K Kong, E Paramithiotis, C L Chen, M J Ratcliffe, T F Davison, J R Young

Publikováno v: The Journal of Immunology. 154:4485-4494

Expression screening has been used to clone cDNAs encoding the alpha- and beta-chains of chicken CD8. Amino acid sequence similarities with the mammalian sequences were about 30%. Many amino acid residues of structural or functional importance were m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::330b328c4b47851a16712198c6246af2
https://doi.org/10.4049/jimmunol.154.9.4485

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Monomeric homologue of mammalian CD28 is expressed on chicken T cells

Autor: J R Young, T F Davison, C A Tregaskes, M C Rennie, O Vainio

Publikováno v: The Journal of Immunology. 152:3848-3851

A mAb recognizing a 40- to 44-kDa monomeric molecule on the surface of chicken T cells was used to screen a cDNA expression library made from Con A-stimulated chicken spleen cells. The sequence of the cDNA obtained encoded a molecule having 50% amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c15632f7addd4f7025755964e68cd1f3
https://doi.org/10.4049/jimmunol.152.8.3848

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The structure of avian CD5 implies a conserved function

Autor: R, Koskinen, T W, Göbel, C A, Tregaskes, J R, Young, O, Vainio

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(10)

The chicken CD5 cDNA was isolated by COS cell expression cloning utilizing a novel mAb 2-191. The cDNA contains a 1422-nucleotide open reading frame encoding a mature protein with 32% and 30% identity to mouse and human CD5 polypeptides, respectively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1e73345817a80c146b5a45076fc0510
https://pubmed.ncbi.nlm.nih.gov/9590242

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