Výsledky vyhledávání - "C. A. Sorkness"

Effects of montelukast (MK-0476); a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids

Autor: W Stricker, Ji Zhang, C A Sorkness, S Kundu, Theodore F. Reiss, William W. Busse, A Botto

Publikováno v: Thorax. 52:45-48

BACKGROUND: Cysteinyl leukotriene release in association with airway inflammation is a feature of clinical asthma. The acute effects of montelukast (MK-0476), a potent, orally administered, specific cysteinyl leukotriene receptor antagonist, on airwa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ae5baf3e57d720ddd65bbf47d9d33f
https://doi.org/10.1136/thx.52.1.45

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Allergen-specific IgE as a biomarker of exposure plus sensitization in inner-city adolescents with asthma

Autor: E C, Matsui, H A, Sampson, H T, Bahnson, R S, Gruchalla, J A, Pongracic, S J, Teach, P J, Gergen, G R, Bloomberg, J F, Chmiel, A H, Liu, M, Kattan, C A, Sorkness, S F, Steinbach, R E, Story, C M, Visness

Publikováno v: Allergy. 65(11)

Relationships among allergen-specific IgE levels, allergen exposure and asthma severity are poorly understood since sensitization has previously been evaluated as a dichotomous, rather than continuous characteristic.Five hundred and forty-six inner-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b38bd5d25996daa90043981bc0aa9fb
https://pubmed.ncbi.nlm.nih.gov/20560910

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Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial

Autor: R F, Lemanske, C A, Sorkness, E A, Mauger, S C, Lazarus, H A, Boushey, J V, Fahy, J M, Drazen, V M, Chinchilli, T, Craig, J E, Fish, J G, Ford, E, Israel, M, Kraft, R J, Martin, S A, Nachman, S P, Peters, J D, Spahn, S J, Szefler

Publikováno v: JAMA. 285(20)

Inhaled long-acting beta(2)-agonists improve asthma control when added to inhaled corticosteroid (ICS) therapy.To determine whether ICS therapy can be reduced or eliminated in patients with persistent asthma after adding a long-acting beta(2)-agonist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b8c95dcb18989d7189179f3b7b52c69
https://pubmed.ncbi.nlm.nih.gov/11829556

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Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial

Autor: S C, Lazarus, H A, Boushey, J V, Fahy, V M, Chinchilli, R F, Lemanske, C A, Sorkness, M, Kraft, J E, Fish, S P, Peters, T, Craig, J M, Drazen, J G, Ford, E, Israel, R J, Martin, E A, Mauger, S A, Nachman, J D, Spahn, S J, Szefler

Publikováno v: JAMA. 285(20)

Long-acting beta(2)-agonists are prescribed for patients with persistent asthma and are sometimes used without inhaled corticosteroids (ICSs). No evidence exists, however, to support their use as monotherapy in adults with persistent asthma.To examin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::545c6bd94a5258736cb9bb36502e8708
https://pubmed.ncbi.nlm.nih.gov/11829555

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Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma

Publikováno v: International archives of allergy and immunology. 124(1-3)

Regular use of inhaled beta-adrenergic agonists may have adverse effects in some asthma patients. Polymorphisms of the beta(2)-adrenergic receptor (beta(2)-AR) can affect its regulation; however, results of smaller studies of the effects of such poly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9015511320f33c30858e90a8eb525ae3
https://pubmed.ncbi.nlm.nih.gov/11306963

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Establishing a therapeutic index for the inhaled corticosteroids: part II. Comparisons of systemic activity and safety among different inhaled corticosteroids

Autor: C A, Sorkness

Publikováno v: The Journal of allergy and clinical immunology. 102(4 Pt 2)

The systemic activity and safety of inhaled corticosteroids are best studied in randomized, controlled, long-term trials with clinically relevant doses in subjects. These studies require large numbers of enrolled subjects and are difficult to conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::369a3ecb0460ce5b3b57da0c44e51abf
https://pubmed.ncbi.nlm.nih.gov/9798723

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The use of 5-lipoxygenase inhibitors and leukotriene receptor antagonists in the treatment of chronic asthma

Autor: C A, Sorkness

Publikováno v: Pharmacotherapy. 17(1 Pt 2)

With the elucidation of asthma as a chronic inflammatory disease, therapeutic approaches have shifted from treatment of symptoms with bronchodilators to treatment of the underlying disease with antiinflammatory agents. Along with concerns about corti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db3e8b35fec1faa1e6d05c9c72e254b1
https://pubmed.ncbi.nlm.nih.gov/9017788

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Outcome assessment of pain: functional status measures and quality of life as therapeutic endpoints

Autor: C A, Sorkness

Publikováno v: Topics in hospital pharmacy management. 10(2)

These studies and others will provide tools for cancer treatment centers to integrate pain management into comprehensive care strategies. Pharmacists in all health care settings where the cancer patient with pain is being treated should take leadersh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bad41e151475be7593a8991a16415267
https://pubmed.ncbi.nlm.nih.gov/10128564

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