Zobrazeno 1 - 10
of 100
pro vyhledávání: '"C. A. Pierson"'
Publikováno v:
The Malaysian journal of pathology. 41(1)
Intratumoral calcification is a feature that is more often observed in pineal parenchymal tumour than germinoma. We describe a 13-year-old male with pineal region germinoma demonstrating extensive intratumoral calcification.He presented with worsenin
Autor:
Aaron M. Sturm, James A. Eckstein, Martin Bard, Robert J. Barbuch, Caiqing Mo, N. T. Culbertson, C. A. Pierson, K. M. Rogers, N. D. Lees
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:3425-3435
The fungal end product sterol, ergosterol, and its biosynthetic pathway are the targets of the majority of the antifungal compounds currently in use for human infections and agricultural applications. The primary class of compounds used in human infe
Autor:
Martin Bard, Huei Fung Tsai, Anna A. Krol, Aaron M. Sturm, Koichi Izumikawa, John E. Bennett, Nicholas T. Culbertson, C. A. Pierson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2483-2489
A Candida glabrata erg1 ( Cgerg1 ) mutant, CgTn201S, was identified by transposon mutagenesis and by increased fluconazole susceptibility. CgERG1 encodes a 489-amino-acid protein which, on the basis of its homology with Saccharomyces cerevisiae ERG1
Publikováno v:
Medical Mycology. 42:385-389
The ergosterol pathway is the major target of the azole antifungals. We have developed a panel of five viable ergosterol biosynthetic mutants (erg2, erg3, erg6, erg11 and erg24) and have performed Northern analyses to study transcriptional regulation
Publikováno v:
FEMS Yeast Research. 1:93-101
The Candida albicans ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) was cloned by complementing a Saccharomyces cerevisiae erg26 mutant with a C. albicans genomic library. Sequence analysis showed a 70% identity between the C. a
Publikováno v:
Proceedings of the National Academy of Sciences. 94:11173-11178
Genetic disruption of the Saccharomyces cerevisiae C-4 sterol methyl oxidase ERG25 gene leads to sterol auxotrophy. We have characterized a suppression system that requires two mutations to restore viability to this disrupted strain. One suppressor m
Autor:
Susan G. Elner, A. K. Vine, A Jr Capone, D. S. Coffman, C. N. Moore, S. R. Sneed, Jennifer I. Lim, S. K. Gardner, P Jr Sternberg, Dennis P. Han, L. M. Jessup, B. A. Blodi, C. L. Pierson, F. McIver, J. Willis, T. M. Aaberg, Mark W. Johnson, S. Stanley, S. Khanderia
Publikováno v:
American Journal of Ophthalmology. 122:830-846
To evaluate the relationship between microbiologic factors, effect of treatment, and visual outcome in the Endophthalmitis Vitrectomy Study.Four hundred twenty patients were enrolled in the Endophthalmitis Vitrectomy Study between February 1990 and J
Autor:
N. D. Lees, Robert J. Barbuch, C. A. Pierson, Leah L. Frye, B Biermann, D A Bruner, Martin Bard, C. Koegel
Publikováno v:
Proceedings of the National Academy of Sciences. 93:186-190
We have cloned the Saccharomyces cerevisiae C-4 sterol methyl oxidase ERG25 gene. The sterol methyl oxidase performs the first of three enzymic steps required to remove the two C-4 methyl groups leading to cholesterol (animal), ergosterol (fungal), a
Autor:
C. A. Pierson, Margaret H. Lai, Donald R. Kirsch, Guy T. Carter, Martin Bard, John F.Alexander, Mark G. Goebl
Publikováno v:
Gene. 140:41-49
The Saccharomyces cerevisiae ERG24 gene, encoding sterol Δ14 reductase (Erg24p), was cloned by selecting strains carrying sequences on a 2μ-based vector for resistance to the morpholine fungicide, fenpropimorph (Fp). Four distinct plasmid inserts w
Publikováno v:
International Journal of Obstetric Anesthesia. 11:252-254
In order to estimate how long a medication can remain prepared before the integrity or concentration of the drug is compromised, we assessed the sterility and potency of medications commonly used in our obstetric anesthesia practice. Our goal was to