Zobrazeno 1 - 10
of 19
pro vyhledávání: '"C. A. Perks"'
Autor:
P. J. Gilvin, C. A. Perks
Publikováno v:
Radiation Protection Dosimetry. 144:102-106
Recent years have seen the increasing use of passive dosemeters that have high sensitivities and, in laboratory conditions, detection limits of
Publikováno v:
Minerva endocrinologica. 37(2)
The major issue currently being faced in the management of prostate cancer is the inability to distinguish between indolent prostate tumors that will not present clinically from more aggressive and metastatic prostate cancers that will impact on men'
Publikováno v:
Radiation protection dosimetry. 125(1-4)
A new external monitoring service has been developed combining the excellent features of optically stimulated luminescence (OSL) with the convenience of Panasonic readers. This article briefly reviews OSL, and describes the InLight personal dosimetry
Publikováno v:
Experimental dermatology. 12(4)
In this study, we have examined the effects of retinoic acid (RA) on the human immortalized keratinocyte cell line (HaCaT). A significant twofold (P0.01) increase in apoptotic cell death compared with the control was found within 24 h of treatment wi
Publikováno v:
Journal of cellular biochemistry. 80(2)
We have demonstrated previously in Hs578T cells that insulin-like growth factor binding protein (IGFBP)-3 can significantly accentuate ceramide (C2)-induced apoptosis, but has no effect on cell death induced by integrin detachment [using an arginine-
Publikováno v:
International journal of cancer. 88(3)
Neoplastic transformation is characterised by an imbalance in favour of cell growth over programmed cell death (apoptosis). The tumour-suppressor gene p53, responsible for maintaining cell-cycle control, is mutated in the majority of human cancers. L
Publikováno v:
International journal of cancer. 88(3)
Variability in response to chemotherapy is poorly understood. Paclitaxel-induced apoptosis was assessed in human Hs578T breast cancer cells, using the MTT assay, cell counting, morphological features and flow cytometry. Pre-dosing cells with non-glyc
Autor:
C M, Perks, J M, Holly
Publikováno v:
Journal of mammary gland biology and neoplasia. 5(1)
The IGFBP family comprises six proteins with high affinity for the IGFs and several lower affinity IGFBP-related proteins. Their production in the breast is controlled by hormones, other local regulators and in tumors relates to the estrogen receptor
Publikováno v:
Journal of cellular biochemistry. 75(4)
We have demonstrated previously that insulin-like growth factor binding protein (IGFBP)-3 alone has little growth inhibitory effect on Hs578T human breast cancer cells, but that it can dramatically accentuate the apoptotic response to the physiologic
Publikováno v:
International journal of cancer. 82(3)
Despite the increase in laser therapy, concern remains that sublethal treatment of pre-malignant lesions may adversely affect the biological behaviour of surviving cells. Integrin receptors mediate interaction of cells with the extracellular matrix a