Zobrazeno 1 - 10
of 16
pro vyhledávání: '"C. A. Parkos"'
Publikováno v:
Clinical and Experimental Immunology. 184:347-357
Summary Noroviruses (NoV) are the most common cause of epidemic gastroenteritis world-wide. NoV infections are often asymptomatic, although individuals still shed large amounts of NoV in their stool. Understanding the differences between asymptomatic
Publikováno v:
Clinical and Experimental Immunology. 182:195-203
Summary Noroviruses (NoV) are the most common cause of epidemic gastroenteritis worldwide. The acute immune response to NoV in humans is poorly understood, hindering research on prevention and treatment. To elucidate the acute immune response and tes
Autor:
S P Colgan, M B Resnick, C A Parkos, C Delp-Archer, D McGuirk, A E Bacarra, P F Weller, J L Madara
Publikováno v:
The Journal of Immunology. 153:2122-2129
Intestinal epithelia are in intimate contact with subepithelial and intraepithelial lymphocytes. When stimulated, mucosal lymphocytes generate inflammatory cytokines such as IL-4 and IFN-gamma. We have shown that IFN-gamma directly regulates epitheli
Publikováno v:
The Journal of biological chemistry. 276(43)
CD47, a cell surface glycoprotein, plays an important role in modulating neutrophil (PMN) migration across endothelial and epithelial monolayers. Here we show that anti-CD47 monoclonal antibodies (mAbs) delay PMN migration across collagen-coated filt
Autor:
L, Mazzucchelli, J B, Burritt, A J, Jesaitis, A, Nusrat, T W, Liang, A T, Gewirtz, F J, Schnell, C A, Parkos
Publikováno v:
Blood. 93(5)
Analysis of peptide binding to human neutrophils (PMN) using phage display techniques has revealed cell-specific motifs reactive with the PMN surface. Phage libraries displaying either linear 9-mer or cyclic 10-mer and 6-mer peptides were incubated w
Publikováno v:
Journal of cellular physiology. 176(1)
Mucosal tissues, such as the lung and intestine, are primary targets for ischemic damage. Under these conditions, neutrophil (polymorphonuclear leukocyte; PMN) infiltration into the protective epithelium has been implicated as a pathophysiologic medi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(10)
In the intestine, lung, and urinary tract, neutrophil (polymorphonuclear leukocyte, PMN) transepithelial migration is dependent on the leukocyte beta2 integrin CD11b/CD18. While the regions of CD11b involved in recognition of several soluble ligands
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(1)
Modeling Salmonella-epithelial cell interaction in vitro has led to the realization that epithelial cells are crucial in orchestrating neutrophil (PMN) responses, in part by stimulating basolateral release of epithelial chemokines, including IL-8. Ho
Autor:
C A, Parkos
Publikováno v:
The American journal of physiology. 273(4)
In many inflammatory conditions of the gastrointestinal tract, disease activity and patient symptoms correlate with the histological finding of neutrophil (PMN) migration across the epithelium. PMN interactions with intestinal epithelium can influenc
Publikováno v:
Methods in enzymology. 255
The availability of sufficient quantities of highly purified phagocyte cytochrome b-558 has been necessary for many of the biochemical and immunological analyses of this important NADPH oxidase component, and it was only through the analysis of highl