Zobrazeno 1 - 8
of 8
pro vyhledávání: '"C. A. Maniglia"'
Publikováno v:
Biochemical Journal. 284:589-593
Bovine articular cartilage was cultured both in the presence and in the absence of human recombinant interleukin-1 alpha (IL-1) (100 units/ml). Addition of this cytokine stimulated matrix degradation approx. 3-fold. This increased degradation permitt
Publikováno v:
Matrix (Stuttgart, Germany). Supplement. 1
Stromelysin/Transin is a member of the matrix metalloprotease gene family. This metalloprotease is synthesized as a preproenzyme with a predicted size of 53,977 Da including a 17 amino acid signal peptide. Prostromelysin is secreted from normal and t
Publikováno v:
Agents and actions. 34(1-2)
Intradermal immunization of female Lewis rats with 100 micrograms of a nine-amino acid synthetic peptide corresponding to the arthritic T cell-reactive epitope of mycobacterial heat shock protein, three weeks prior to induction of adjuvant arthritis,
Publikováno v:
Cancer research. 50(12)
Constituents of the bone marrow microenvironment have the capacity to influence both normal and malignant hematopoietic cell behavior. For example, HL-60 human promyelocytic leukemia cells in vitro display a more mature phenotype when grown on a bone
Publikováno v:
Blood. 70:1119-1123
The initiation and maintenance of cellular differentiation for a variety of cell types has been shown to be influenced by the microenvironment. To investigate the influence of bone marrow stroma on leukemic cell differentiation, HL-60 human promyeloc
Publikováno v:
Journal of the National Cancer Institute. 75(1)
Three cloned B16 murine melanoma cell lines were characterized with respect to their ability to a) detach from a plastic tissue culture substratum, b) form experimental pulmonary metastases, and c) produce and process glycosaminoglycans (GAGS). All t
Publikováno v:
Cancer research. 44(7)
Glycosaminoglycans (GAGs) are polyanionic components of the cell surface that have been shown to play an important role in the cellular differentiation of many embryonic systems, as well as in the maturation of the developing human leukocyte. For thi
Publikováno v:
Journal of the National Cancer Institute. 76(4)
The antithrombotic compound nafazatrom was evaluated in several in vivo and in vitro assays to elucidate the mechanism of its antimetastatic activity. C57BL/6 mice bearing B16 amelanotic subcutaneous tumors treated with 100 mg nafazatrom/kg/day exhib