Výsledky vyhledávání - "C. A. M. La Porta"

Akademický článek

Salivary proteomic profile of young healthy subjects

Autor: P. Dongiovanni, M. Meroni, Gilda Aiello, A. D’Amato, N. Cenzato, S. Casati, G. Damiani, C. Fenoglio, D. Galimberti, E. Grossi, D. Prati, G. Lamorte, C. Bianco, L. Valenti, A. Soggiu, S. Zapperi, C. A. M. La Porta, M. Del Fabbro, G. M. Tartaglia

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

Background: The incidence of noncommunicable diseases (NCDs) has been rapidly ramped up worldwide. Hence, there is an urgent need to non-invasively detect NCDs possibly by exploiting saliva as a ‘liquid biopsy’ to identify biomarkers of the healt

Externí odkaz: https://doaj.org/article/f0a4bd289d2847cd970a9c52f7ffa6c2

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Cellular pathways affected by carbon nanopowder-benzo(α)pyrene complex in human skin fibroblasts identified by proteomics

Autor: L. Del Giacco, C. A. M. La Porta, Nadia Santo, Claudia Landi, Andrea Binelli, Federico Mutti, C. Della Torre, L. Madaschi, Emilio Ciusani, Daniela Maggioni, Miriam Ascagni, Alessandro Armini, Anna Ghilardi, Maria Chiara Lionetti, Luca Bini, Valentina Coccè, Stefano Magni

Publikováno v: Ecotoxicology and environmental safety. 160

One of the crucial and unsolved problems of the airborne carbon nanoparticles is the role played by the adsorbed environmental pollutants on their toxicological effect. Indeed, in the urban areas, the carbon nanoparticles usually adsorb some atmosphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219b24a25551f41ccd4598f47f439c2b
https://pubmed.ncbi.nlm.nih.gov/29803189

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Carbon nanopowder acts as a Trojan-horse for benzo(α)pyrene in Danio rerio embryos

Autor: Luca Bini, Andrea Binelli, Claudia Landi, C. Della Torre, Daniela Maggioni, Stefano Magni, L. Del Giacco, Alessandro Armini, Anna Ghilardi, Miriam Ascagni, Laura Prosperi, L. Madaschi, Marco Parolini, C. A. M. La Porta, Nadia Santo

Carbon-based nanoparticles (CBNs) are largely distributed worldwide due to fossil fuel combustion and their presence in many consumer products. In addition to their proven toxicological effects in several biological models, attention in recent years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4b512324c3b283049854110a788afb
http://hdl.handle.net/11365/1006250

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Human skin-derived fibroblasts used as a 'Trojan horse' for drug delivery

Autor: A. Vitale, C. A. M. La Porta, Emilio Ciusani, Valentina Coccè, Augusto Pessina, Maura Brambilla, Eugenio Parati, Arianna Bonomi, S. Colombo, Paolo Brambilla, Francesca Sisto, Giulio Alessandri

Publikováno v: Clinical and experimental dermatology. 41(4)

SummaryBackground Drug toxicity currently represents the main challenge of tumour chemotherapy. Our group recently developed a new method for drug delivery inspired by the ‘Trojan Horse’ concept. Human mesenchymal stem cells (hMSCs) have been sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729c9738c4cb4d558f502b903424a813
https://pubmed.ncbi.nlm.nih.gov/26899383

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Increased plasma levels of soluble CD40, together with the decrease of TGFβ1, as possible differential markers of Alzheimer disease

Autor: Alessandra Mocali, C. A. M. La Porta, M. Bontempelli, V.A.M. Mitidieri, A. Bavazzano, N. Della Malva, Sabrina Cedrola, Roberto Comolli, Francesco Paoletti

Publikováno v: Experimental Gerontology. 39:1555-1561

Alzheimer's disease (AD) is a progressive neurodegenerative illness and the most frequent cause of dementia in the elderly. The identification of activated microglia within neuritic plaques, coupled with the presence of numerous inflammatory proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bae63b7856520d25ca74d27dd78f3c
https://doi.org/10.1016/j.exger.2004.07.007

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Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors

Autor: Marco Ballarini, Floriana Facchetti, S Previdi, Saverio Minucci, C. A. M. La Porta, Paola Perego

Publikováno v: Apoptosis. 9:573-582

Valproic acid (VPA, 2-propylpentanoic acid) is an established drug in the long-term therapy of epilepsy. Recently, VPA was demonstrated to inhibit histone deacetylases (HDACs) class I enzyme at therapeutically relevant concentrations, thereby, mimick

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c0c22b1fb49125643ab165e2f59e15
https://doi.org/10.1023/b:appt.0000038036.31271.50

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Overexpression of nPKCδ in BL6 murine melanoma cells enhances TGFβ1 release into the plasma of metastasized animals

Autor: C. A. M. La Porta, Roberto Comolli

Publikováno v: Melanoma Research. 10:527-534

Transforming growth factor-beta (TGFbeta) contributes to the promotion of invasion, metastasis, angiogenesis and even immunosuppression. Since overexpression of the delta isoform of protein kinase C (nPKCdelta) in BL6 murine melanoma cells (BL6T cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83db0263fc9965ed7f676fb43ee4a70c
https://doi.org/10.1097/00008390-200012000-00003

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Overexpression of novel protein kinase C δ in BL6 murine melanoma cells inhibits the proliferative capacity in vitro but enhances the metastatic potential in vivo

Autor: Danilo Porro, C. A. M. La Porta, A. Di Dio, Roberto Comolli

Publikováno v: Scopus-Elsevier

In this study we analysed the effect of overexpressing novel protein kinase C delta isoform (n-PKC delta) on melanin synthesis and metastatic potential in the highly metastatic BL6 murine melanoma cells. The proliferative capacity in vitro and into m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee080a1b86c1f9717ad0bd9993be18c
https://doi.org/10.1097/00008390-200004000-00001

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[Untitled]

Autor: C. A. M. La Porta, Roberto Comolli

Publikováno v: Clinical and Experimental Metastasis. 18:361-369

Bryostatin 1 and phorbol esters reduce the intracellular melanin level in high metastatic overexpressing nPKCδ BL6 (BL6T) cells, thereby inducing white experimental metastasis in syngeneic mice. We evaluate here the possible differences between whit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8f65c30de86f0cd4f555e99bac3e67f
https://doi.org/10.1023/a:1010913907830

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