Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C. A. M. Jongenelen"'
Autor:
M, de Jager, M V, Boot, J G J M, Bol, J J P, Brevé, C A M, Jongenelen, B, Drukarch, M M M, Wilhelmus
Publikováno v:
Neuropathology and applied neurobiology. 42(3)
Cerebral amyloid angiopathy (CAA) is a key pathological hallmark of Alzheimer's disease (AD) characterized by accumulation of amyloid-beta (Aβ) protein in blood vessel walls. CAA impairs vessel functioning, affects blood brain barrier integrity and
Autor:
C. A. M. Jongenelen, Jeffrey S. Flier, Benjamin Drukarch, Gerda Andringa, A. N. M. Schoffelmeer
Publikováno v:
Journal of Neural Transmission, 113(5), 593-8. Springer Verlag
Drukarch, B, Flier, J, Jongenelen, C A M, Andringa, G & Schoffelmeer, A N M 2006, ' The antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes ', Journal of Neural Transmission, vol. 113, no. 5, pp. 593-8 . https://doi.org/10.1007/s00702-005-0350-0
Drukarch, B, Flier, J, Jongenelen, C A M, Andringa, G & Schoffelmeer, A N M 2006, ' The antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes ', Journal of Neural Transmission, vol. 113, no. 5, pp. 593-8 . https://doi.org/10.1007/s00702-005-0350-0
Anethole dithiolethione (ADT) is a clinically available, pluripotent antioxidant proposed as a neuroprotectant for Parkinson's disease (PD). Here, using extracts from cultured astrocytes, containing both monoamine oxidase (MAO) A and B activity, we d
Autor:
Cornelis H. Langeveld, Erik Ch. Wolters, Benjamin Drukarch, Johannes C. Stoof, C. A. M. Jongenelen, R. J. Vermeulen
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 269:121-125
Measuring dopamine D1 receptor stimulated cyclic AMP production in cultured astrocytes from rat, monkey and human brain, we demonstrate that the 'classical' drug SKF 38393 (7,8-dihydroxy-1- phenyl-2,3,4,5-tetrahydro-1 H-3-benzazepine) is a partial ag
Publikováno v:
Neuroscience Letters, 416(1), 76-81. Elsevier Ireland Ltd
Andringa, G, Jongenelen, C A M, Halfhide, L & Drukarch, B 2007, ' The thiol antioxidant 1,2-dithiole-3-thione stimulates the expression of heat shock protein 70 in dopaminergic PC12 cells ', Neuroscience Letters, vol. 416, no. 1, pp. 76-81 . https://doi.org/10.1016/j.neulet.2007.01.043
Andringa, G, Jongenelen, C A M, Halfhide, L & Drukarch, B 2007, ' The thiol antioxidant 1,2-dithiole-3-thione stimulates the expression of heat shock protein 70 in dopaminergic PC12 cells ', Neuroscience Letters, vol. 416, no. 1, pp. 76-81 . https://doi.org/10.1016/j.neulet.2007.01.043
In Parkinson's disease (PD), the pathogenic factors oxidative stress and protein aggregation interact and culminate in the apoptotic death of (mainly catecholaminergic) neurons. The dithiolethiones comprise thiol antioxidants that are well known for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a636aad56ec9d22af4b20b46dcbcddc
https://research.vumc.nl/en/publications/ab608f93-d93d-4295-8804-63ca8503e933
https://research.vumc.nl/en/publications/ab608f93-d93d-4295-8804-63ca8503e933
Autor:
Johannes C. Stoof, C. A. M. Jongenelen, Benjamin Drukarch, Eric Schepens, Cornelis H. Langeveld
Publikováno v:
Brain research. 770(1-2)
Astrocytes promote the survival of neurons. Conditions characterized by loss of neurons, such as aging and aging-related neurodegenerative disorders, are accompanied by both disturbances in astrocyte-neuron interactions and signs of oxidative damage.
Autor:
Gerda Andringa, A.M. Van Dam, Benjamin Drukarch, John G.J.M. Bol, C. A. M. Jongenelen, J. Hoozemans, M. Wilhelmus, A. Boekel, J. Breve
Publikováno v:
Parkinsonism & Related Disorders. 13:S135