Zobrazeno 1 - 10
of 39
pro vyhledávání: '"C. A. Houser"'
Autor:
Mei C. Q. Houser, Shane P. C. Mitchell, Priyanka Sinha, Brianna Lundin, Oksana Berezovska, Masato Maesako
Publikováno v:
Sensors, Vol 23, Iss 5, p 2651 (2023)
Our unique multiplexed imaging assays employing FRET biosensors have previously detected that γ-secretase processes APP C99 primarily in late endosomes and lysosomes in live/intact neurons. Moreover we have shown that Aβ peptides are enriched in th
Externí odkaz:
https://doaj.org/article/feff77a0dfd94dfb90e66cb1b7edaf28
Autor:
Alec K. McKendell, Mei C. Q. Houser, Shane P. C. Mitchell, Michael S. Wolfe, Oksana Berezovska, Masato Maesako
Publikováno v:
Biosensors, Vol 12, Iss 8, p 663 (2022)
Amyloid-beta (Aβ) peptides are produced within neurons. Some peptides are released into the brain parenchyma, while others are retained inside the neurons. However, the detection of intracellular Aβ remains a challenge since antibodies against Aβ
Externí odkaz:
https://doaj.org/article/fd9e8fa427f84466aa0ca2ba63adb949
Autor:
Mei C. Q. Houser, Yuliia Turchyna, Florian Perrin, Lori Chibnik, Oksana Berezovska, Masato Maesako
Publikováno v:
Biosensors, Vol 11, Iss 6, p 169 (2021)
Presenilin (PS)/γ-secretase is an aspartyl protease that processes a wide range of transmembrane proteins such as the amyloid precursor protein (APP) and Notch1, playing essential roles in normal biological events and diseases. However, whether ther
Externí odkaz:
https://doaj.org/article/a33e9e7e9c9540cf8abd6d6be3653847
Publikováno v:
J Neurosci
Presenilin (PSEN)/γ-secretase is a protease complex responsible for the proteolytic processing of numerous substrates. These substrates include the amyloid precursor protein (APP), the cleavage of which by γ-secretase results in the production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ecd9db8bc872ad80e5b4e4ebddc29d
https://pubmed.ncbi.nlm.nih.gov/34810230
https://pubmed.ncbi.nlm.nih.gov/34810230
Autor:
Oksana Berezovska, Mei C. Q. Houser, Florian Perrin, Brian J. Bacskai, Yuliia Turchyna, Steven S. Hou, Masato Maesako
Publikováno v:
Sensors (Basel, Switzerland)
Sensors, Vol 20, Iss 5980, p 5980 (2020)
Sensors
Volume 20
Issue 21
Sensors, Vol 20, Iss 5980, p 5980 (2020)
Sensors
Volume 20
Issue 21
Presenilin (PS)/&gamma
secretase plays a pivotal role in essential cellular events via proteolytic processing of transmembrane proteins that include APP and Notch receptors. However, how PS/&gamma
secretase activity is spatiotemporally regu
secretase plays a pivotal role in essential cellular events via proteolytic processing of transmembrane proteins that include APP and Notch receptors. However, how PS/&gamma
secretase activity is spatiotemporally regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df14fa8c122793537822e702e81bdb1d
https://doi.org/10.3390/s20215980
https://doi.org/10.3390/s20215980
Autor:
C R, Houser
Publikováno v:
Advances in neurology. 79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01c0aeed302bef6882a2f63775993575
https://pubmed.ncbi.nlm.nih.gov/10514861
https://pubmed.ncbi.nlm.nih.gov/10514861
Autor:
S, Dupuy-Davies, C R, Houser
Publikováno v:
Hippocampus. 9(2)
In recent studies, we demonstrated a distinct change in the distribution of glutamate decarboxylase 67 (GAD67) mRNA-containing neurons within the rat dentate gyrus from embryonic day 20 (E20) to postnatal day 15 (PN15) (Dupuy and Houser, J Comp Neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2755ece5e7786b0c45c05e7a450ecd51
https://pubmed.ncbi.nlm.nih.gov/10226778
https://pubmed.ncbi.nlm.nih.gov/10226778
Autor:
N, Zhang, C R, Houser
Publikováno v:
The Journal of comparative neurology. 405(4)
Substantial reorganization of mossy fibers from granule cells of the dentate gyrus occurs in a high percentage of humans with medically intractable temporal lobe epilepsy. To identify these fibers and determine their ultrastructural features in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::142d82d7d3fa2466099978fbad41a2b0
https://pubmed.ncbi.nlm.nih.gov/10098940
https://pubmed.ncbi.nlm.nih.gov/10098940
Autor:
S T, Dupuy, C R, Houser
Publikováno v:
The Journal of comparative neurology. 389(3)
The temporal and spatial distribution of glutamate decarboxylase 67 (GAD67) mRNA-containing neurons in the dentate gyrus was analyzed from embryonic day 20 (E20) to postnatal day 15 (PN15) with nonradioactive in situ hybridization methods. A major go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dac4f6d157f80c2eb46b45e5f332c6be
https://pubmed.ncbi.nlm.nih.gov/9414003
https://pubmed.ncbi.nlm.nih.gov/9414003
Publikováno v:
Hippocampus. 6(3)
The alpha 1 subunit of the gamma-aminobutyric acid (GABA)A receptor is highly expressed in a subgroup of neurons in the hippocampal formation. The distribution and chemical identities of these neurons in the dentate gyrus have been studied with doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42ea86d2477e37b0b362885eb4c9c25a
https://pubmed.ncbi.nlm.nih.gov/8841823
https://pubmed.ncbi.nlm.nih.gov/8841823