Výsledky vyhledávání - "C., Kandeepan"

ADMETox-informatics of Plant Derived Octadecanoic Acid (Stearic Acid) from Ethyl Acetate Fraction of Moringa oleifera Leaf Extract as a Natural Lead for Next Generation Drug Design, Development and Therapeutics

Autor: Ram Chand Dhakar, GC. Abraham, G Grace Lydial Pushpalatha, D. Kandavel, S. Sutha, P. Kaliraj, G. Pandiarajan, T. Loganathan, R. Jayakumararaj, S. Ramya, B. Mathialagan, N. Senthilkumar, C. Kandeepan, A Pallan. Gilles, A.N. Basha, K. Krishnaveni, R.V. Kalaimathi, M. Murugan

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:129-141

In-silico Computer-Aided Drug Design (CADD) significantly relies on cybernetic screening of Plant Based Natural Products (PBNPs) as a prime source of bioactive compounds/ drug leads due to their unique chemical structural scaffolds and distinct funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b86dce542dca49a069053976cbf9274
https://doi.org/10.22270/jddt.v12i6.5677

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ADMET-Evaluation, Pharmacokinetics, Drug-likeness and Medicinal Chemistry of GCMS Identified Bioactive Compounds of Moringa oleifera Natural-Ripened-Dried Methanolic Pod Extract (MOMPE) as a Potential Source of Natural Drug Frontrunner for Next Generation

Autor: R. Jayakumararaj, J. King Immanuel, GC. Abraham, G Grace Lydial Pushpalatha, S. Ramya, Sanyam Gandhi, Mohamed Ali Seyed, S. Sutha, N. Senthilkumar, N. Kavitha, A. Jeevalatha, K. Suganandam, C. Kandeepan

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:65-85

Over centuries, Moringa oleifera has been used as an integral part of Ayurveda, Siddha and Unani systems of medicine, besides this miracle tree has a wide range of nutritional and bioactive compounds, including proteins, essential amino acids, carboh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4603f97d125c400f698e5527c9cf1fd6
https://doi.org/10.22270/jddt.v12i6.5668

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Profile of Phytochemicals and GCMS Analysis of Bioactive Compounds in Natural Dried-Seed Removed Ripened Pods Methanolic Extracts of Moringa oleifera

Autor: R. Jayakumararaj, GC. Abraham, G Grace Lydial Pushpalatha, S. Ramya, Sanyam Gandhi, Mohamed Ali Seyed, S. Sutha, N. Senthilkumar, N. Kavitha, C. Kandeepan, A. Jeevalatha, K. Suganandam

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:133-141

Moringa oleifera has been reported to be the store-house of wide range of bioactive compounds. Most commonly used plant part has been the leaves which are reported to be rich in Vitamins, Carotenoids, Polyphenols, Phenolic Acids, Flavonoids Alkaloids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4e5f2fd62710fa41ca16712606e3b27
https://doi.org/10.22270/jddt.v12i5-s.5657

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ADMET informatics of Plant Derived n-Hexadecanoic Acid (Palmitic Acid) from ethyl acetate fraction of Moringa oleifera leaf extract

Autor: Ram Chand Dhakar, P. Kaliraj, G. Pandiarajan, T. Loganathan, R. Jayakumararaj, S. Ramya, B. Mathialagan, N. Senthilkumar, C. Kandeepan, GA. Pallan, AN. Basha, RV. Kalaimathi, M. Murugan, K. Krishnaveni

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:132-145

Palmitic Acid (PA) is known to exert multiple fundamental biological functions at cellular and tissue levels and its steady concentration is guaranteed by its endogenous synthesis by DNL. PA has been for a long time negatively represented for its det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8384390b78d80481ce5587dfddc5aadd
https://doi.org/10.22270/jddt.v12i5.5605

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Artificial Intelligence and Machine Learning approach based in-silico ADME-Tox and Pharmacokinetic Profile of α-Linolenic acid from Catharanthus roseus (L.) G. Don

Autor: R. Jayakumararaj, C Kandeepan, T. Ponrathy, GC. Abraham, S. Balamurugan, T. Loganathan, Devaraj Aruna, G. Grace Lydial Pushpalatha, C. Soorya, S. Ramya

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:96-109

Current craze and concomitant rise of Artificial Intelligence and Machine Learning (AI&ML) in the post-COVID-era holds significant contribution to Drug Design and Development. Along with IoT, AI&ML has reduced human interface and improved the Quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f229ecf1591a4092e882d5dff403719
https://doi.org/10.22270/jddt.v12i2-s.5274

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In-silico Absorption, Distribution, Metabolism, Elimination and Toxicity profile of 9,12,15-Octadecatrienoic acid (ODA) from Moringa oleifera

Autor: R. Jayakumararaj, L. Ramanathan, NM. Boopathi, S. Ramya, N. Senthilkumar, M. Sabitha, C. Kandeepan, K. Parvathi

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:142-150

9,12,15-Octadecatrienoic acid (ODA) a carboxylic acid composed of 18 carbon atoms and three cis double bonds. ODA is a plant derived essential fatty acid indispensable to the human system. ODA refers to many different structural and conformational is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4afcb3d2fe7dd0bc6aa4488b80217d5
https://doi.org/10.22270/jddt.v12i2-s.5289

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Phytochemical Screening, GCMS Profile, and In-silico properties of Bioactive Compounds in Methanolic Leaf Extracts of Moringa oleifera

Autor: R. Jayakumararaj, NM. Boopathi, S. Ramya, N. Senthilkumar, K. Parvathi, M. Sabitha, C. Kandeepan

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:87-99

Plant Based Natural Products (PBNPs) have been subject of interest since ancient time due to their use in food, industrial and biomedical applications. Research attention has further augmented to explore their phytochemical composition, properties, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9187497f6ced0ff0e23b1ee92292292
https://doi.org/10.22270/jddt.v12i2.5250

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vNN model cross validation towards Accuracy, Sensitivity, Specificity and kappa performance measures of β-caryophyllene using a restricted-unrestricted applicability domain on Artificial Intelligence & Machine Learning approach based in-silico prediction

Autor: R. Jayakumararaj, T. Loganathan, S. Ramya, C. Kandeepan, M. Murugan, M. Sabitha, K. Krishnaveni

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:123-131

Wide-reaching interest in use of plant derived secondary metabolites (PDSMs) has been growing world over. This implies that the beneficial effects of plant based natural products (PBNPs) being rediscovered and harnessed for the development of novel d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de0e360c0438d2658a0af8dd29aa4f16
https://doi.org/10.22270/jddt.v12i1-s.5222

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In-silico Absorption, Distribution, Metabolism, Elimination and Toxicity profile of Isopulegol from Rosmarinus officinalis

Autor: R. Jayakumararaj, T. Loganathan, S. Ramya, C. Kandeepan, Afroze Naveed Basha, A. Jeevalatha, R.V. Kalaimathi

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:102-108

Plant Based Natural Products (PBNPs) have contributed to the development of many drugs for diverse indications. Worldwide interest in use of plants based natural products (PBNPs) has been growing, and its beneficial effects being rediscovered for the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::282f9f83f11e200254734b134fef719f
https://doi.org/10.22270/jddt.v12i1.5188

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Profile of bioactive compounds in Rosmarinus officinalis

Autor: R. Jayakumararaj, T. Loganathan, S. Ramya, C. Kandeepan, Afroze Naveed Basha, R.V. Kalaimathi, A. Jeevalatha

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:114-122

Plant Based Natural Products (PBNPs) have contributed to the development of drugs for diverse indications. Worldwide interest in use of PBNPs has been growing, and its beneficial effects being rediscovered for the development of drug leads. Literatur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ba4f06f2b4e6bde5cb49cbf6ff83ff8
https://doi.org/10.22270/jddt.v12i1.5189

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