Zobrazeno 1 - 10
of 589
pro vyhledávání: '"C-type lectin receptors"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116724- (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the most prevalent liver diseases worldwide, and its occurrence is strongly associated with obesity, insulin resistance (IR), genetics, and metabolic stress. Ranging f
Externí odkaz:
https://doaj.org/article/8f3507d9d486418a812442df83729b7d
Publikováno v:
The Cell Surface, Vol 11, Iss , Pp 100123- (2024)
Herein, this manuscript explores the significance of the phosphoglucomutase (PGM) enzyme in Pneumocystis spp., focusing on its role in fungal surface mannoprotein formation. Through expression of the Pneumocystis murina Pmpgm2 in a Saccharomyces cere
Externí odkaz:
https://doaj.org/article/3ec2e587d8c64200bd5b5835f6975821
Autor:
Maia Chop, Camila Ledo, María Celeste Nicolao, Julia Loos, Andrea Cumino, Christian Rodriguez Rodrigues
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Parasites possess remarkable abilities to evade and manipulate the immune response of their hosts. Echinococcus granulosus is a parasitic tapeworm that causes cystic echinococcosis in animals and humans. The hydatid fluid released by the parasite is
Externí odkaz:
https://doaj.org/article/b02cd779739f4e84bcbbc83b86c72f1e
Autor:
Rossella Bellini, Annalisa Moregola, Jasmine Nour, Patrizia Uboldi, Fabrizia Bonacina, Giuseppe D. Norata
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract Aims Inflammatory pathways and immune system dysregulation participate in the onset and progression of cardiometabolic diseases. The dendritic cell immunoreceptor 2 (DCIR2) is a C‐type lectin receptor mainly expressed by conventional type
Externí odkaz:
https://doaj.org/article/f1d28b6c4e204af5899bbebca36f1de1
Autor:
Rossella Bellini, Annalisa Moregola, Jasmine Nour, Yoann Rombouts, Olivier Neyrolles, Patrizia Uboldi, Fabrizia Bonacina, Giuseppe Danilo Norata
Publikováno v:
Atherosclerosis Plus, Vol 51, Iss , Pp 8-12 (2023)
Background and aims: Atherogenesis results from altered lipid metabolism and impaired immune response. Emerging evidence has suggested that dendritic cells (DCs) participate to atherosclerosis-related immune response, but their impact is scarcely cha
Externí odkaz:
https://doaj.org/article/f2666e69875e4abe80fc3786cf0cd27b
Autor:
Rémi Hatinguais, Madalaine Kay, Fabián Salazar, Daniel P. Conn, David L. Williams, Peter C. Cook, Janet A. Willment, Gordon D. Brown
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Fc-C-type lectin receptor (Fc-CTLRs) probes are soluble chimeric proteins constituted of the extracellular domain of a CTLR fused with the constant fraction (Fc) of the human IgG. These probes are useful tools to study the interaction of CTL
Externí odkaz:
https://doaj.org/article/34801da1a3ac4dc2ac38ef8fe37b8eb5
Autor:
Angela Holder, Jeannine Kolakowski, Chloe Rosentreter, Ellen Knuepfer, Sabine A. F. Jégouzo, Oliver Rosenwasser, Heather Harris, Lotta Baumgaertel, Amanda Gibson, Dirk Werling
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Innate immune receptors that form complexes with secondary receptors, activating multiple signalling pathways, modulate cellular activation and play essential roles in regulating homeostasis and immunity. We have previously identified a variety of bo
Externí odkaz:
https://doaj.org/article/6c8a0461c0404ac38b0aa2331023ccb8
Autor:
Marije E. Kuipers, D. Linh Nguyen, Angela van Diepen, Lynn Mes, Erik Bos, Roman I. Koning, Esther N. M. Nolte-’t Hoen, Hermelijn H. Smits, Cornelis H. Hokke
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Schistosomes can survive in mammalian hosts for many years, and this is facilitated by released parasite products that modulate the host’s immune system. Many of these products are glycosylated and interact with host cells via C-type lectin recepto
Externí odkaz:
https://doaj.org/article/4a5c7cd49774436ea49d296e83632948
Autor:
Judith Schick, Meltem Altunay, Matthew Lacorcia, Nathalie Marschner, Stefanie Westermann, Julia Schluckebier, Christoph Schubart, Barbara Bodendorfer, Dennis Christensen, Christian Alexander, Stefan Wirtz, David Voehringer, Clarissa Prazeres da Costa, Roland Lang
Publikováno v:
eLife, Vol 12 (2023)
The myeloid C-type lectin receptor (CLR) MINCLE senses the mycobacterial cell wall component trehalose-6,6’-dimycolate (TDM). Recently, we found that IL-4 downregulates MINCLE expression in macrophages. IL-4 is a hallmark cytokine in helminth infec
Externí odkaz:
https://doaj.org/article/5ae7b59983a44ed9bd8dcf86dc279bbf
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5790-5812 (2022)
The relevance of protein-glycan interactions in immunity has long been underestimated. Yet, the immune system possesses numerous classes of glycan-binding proteins, so-called lectins. Of specific interest is the group of myeloid C-type lectin recepto
Externí odkaz:
https://doaj.org/article/161193ca96a94f61bf8bb7d4c155f8c7