Zobrazeno 1 - 10
of 52
pro vyhledávání: '"C-Ting Wu"'
Autor:
Yuh Chwen G Lee, Yuki Ogiyama, Nuno M C Martins, Brian J Beliveau, David Acevedo, C-Ting Wu, Giacomo Cavalli, Gary H Karpen
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008673 (2020)
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associa
Externí odkaz:
https://doaj.org/article/4c0e3b422fb940b68348a0335a9e82cd
Autor:
Guy Nir, Irene Farabella, Cynthia Pérez Estrada, Carl G Ebeling, Brian J Beliveau, Hiroshi M Sasaki, S Dean Lee, Son C Nguyen, Ruth B McCole, Shyamtanu Chattoraj, Jelena Erceg, Jumana AlHaj Abed, Nuno M C Martins, Huy Q Nguyen, Mohammed A Hannan, Sheikh Russell, Neva C Durand, Suhas S P Rao, Jocelyn Y Kishi, Paula Soler-Vila, Michele Di Pierro, José N Onuchic, Steven P Callahan, John M Schreiner, Jeff A Stuckey, Peng Yin, Erez Lieberman Aiden, Marc A Marti-Renom, C-Ting Wu
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007872 (2018)
Chromosome organization is crucial for genome function. Here, we present a method for visualizing chromosomal DNA at super-resolution and then integrating Hi-C data to produce three-dimensional models of chromosome organization. Using the super-resol
Externí odkaz:
https://doaj.org/article/cf552eea66d7469391f82a3f33fd4b3e
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006169 (2016)
Following DNA replication, sister chromatids must stay connected for the remainder of the cell cycle in order to ensure accurate segregation in the subsequent cell division. This important function involves an evolutionarily conserved protein complex
Externí odkaz:
https://doaj.org/article/f07dafc491d0478086116b2f4a4e31c7
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004646 (2014)
Ultraconserved elements (UCEs) are strongly depleted from segmental duplications and copy number variations (CNVs) in the human genome, suggesting that deletion or duplication of a UCE can be deleterious to the mammalian cell. Here we address the pro
Externí odkaz:
https://doaj.org/article/d37fe52ce71e4d7e9ff19141ca16af0e
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004013 (2013)
Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can lead to changes in gene expression, chromosome entanglements, and loss-of-heterozygosity due
Externí odkaz:
https://doaj.org/article/121073eeb901426fadf8d7cc49097536
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002667 (2012)
The pairing of homologous chromosomes is a fundamental feature of the meiotic cell. In addition, a number of species exhibit homolog pairing in nonmeiotic, somatic cells as well, with evidence for its impact on both gene regulation and double-strand
Externí odkaz:
https://doaj.org/article/7e71efaea6ca4903bbcd5f8d582ff00b
Autor:
C.-ting Wu, Antonios Lioutas, Guy Nir, Marc A. Marti-Renom, Paul Reginato, George M. Church, Nuno Martins, Shyamtanu Chattoraj, Brian J. Beliveau, Huy Q. Nguyen, Mohammed A. Hannan, Son C. Nguyen, Elliot A. Hershberg, David Castillo, Evan R. Daugharthy
Publikováno v:
Nature methods
There is a need for methods that can image chromosomes with genome-wide coverage, as well as greater genomic and optical resolution. We introduce OligoFISSEQ, a suite of three methods that leverage fluorescence in situ sequencing (FISSEQ) of barcoded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563b53127c3db27bac2c0a2799a777ae
https://doi.org/10.1038/s41592-020-0890-0
https://doi.org/10.1038/s41592-020-0890-0
Publikováno v:
Trends in Genetics. 35:787-790
X inactivation presents two longstanding puzzles: the counting and choice of X chromosomes. Here, we consider counting and choice in the context of pairing, both of the X and of the autosomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dedafae62b08c58166c01b8dd2e6d8
https://doi.org/10.1016/j.tig.2019.07.010
https://doi.org/10.1016/j.tig.2019.07.010
Autor:
Ruth B. McCole, Geoffrey Fudenberg, Leonid A. Mirny, Anton Goloborodko, Jumana AlHaj Abed, Jelena Erceg, Wren Saylor, C.-ting Wu, Job Dekker, Son C. Nguyen, Bryan R. Lajoie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Trans-homolog interactions have been studied extensively in Drosophila, where homologs are paired in somatic cells and transvection is prevalent. Nevertheless, the detailed structure of pairing and its functional impact have not been thoroughly inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef923acf4eafeb36736a83acc98b5bd2
https://doaj.org/article/efe9374eb24d45d29061d1cd4af22228
https://doaj.org/article/efe9374eb24d45d29061d1cd4af22228
Autor:
Gary H. Karpen, Nuno Martins, Yuki Ogiyama, Yuh Chwen G. Lee, Giacomo Cavalli, Brian J. Beliveau, C.-ting Wu, David Acevedo
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2020, 16 (3), pp.e1008673. ⟨10.1371/journal.pgen.1008673⟩
PLoS Genetics, Vol 16, Iss 3, p e1008673 (2020)
PLoS Genetics, vol 16, iss 3
PLoS genetics, vol 16, iss 3
PLoS Genetics, Public Library of Science, 2020, 16 (3), pp.e1008673. ⟨10.1371/journal.pgen.1008673⟩
PLoS Genetics, Vol 16, Iss 3, p e1008673 (2020)
PLoS Genetics, vol 16, iss 3
PLoS genetics, vol 16, iss 3
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6399725a08d536c2e10228e945fd0a67
https://doi.org/10.1101/525873
https://doi.org/10.1101/525873
