Zobrazeno 1 - 10
of 2 235
pro vyhledávání: '"C-C chemokine receptor type 6"'
Autor:
Philip M. Murphy
Publikováno v:
Clinical Immunology ISBN: 9780702081651
Chemokines form a large family composed primarily of small secreted cytokine proteins that coordinate leukocyte trafficking by binding to seven-transmembrane (7TM) domain receptors. Chemokines mediate normal host defense and tissue repair; however, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c81f9a043c464c157bbbcb6e82443f8
https://doi.org/10.1016/b978-0-7020-8165-1.00015-0
https://doi.org/10.1016/b978-0-7020-8165-1.00015-0
Publikováno v:
Immunology Letters. 242:37-45
Involvement of γδ T cells is implicated in the pathogenesis of Behcet's disease (BD) as a bridge between innate and adaptive responses. IL-17 and IL-22 have also been shown to participate in the BD pathogenesis in addition to IFN-γ. Mainly CD4+ T
Publikováno v:
International Journal of Cancer. 150:1373-1391
TNFR2+ regulatory T cells preferentially accumulate in the tumor microenvironment, express high levels of immunosuppressive molecules and possess strong suppressive activity. This study aimed to explore the characteristics and role of TNFR2+ Tregs in
Autor:
Valeria Ramaglia, Jennifer Y. Yam, Camille Grasmuck, Dennis S. W. Lee, Laure Michel, Lyne Bourbonnière, Lesley A. Ward, Amit Bar-Or, Alexandre Prat, Dragos Dasoveanu, Jennifer L. Gommerman, Olga L. Rojas, Stephanie Zandee
Publikováno v:
The Journal of Immunology. 207:1513-1521
B cells have been implicated in the pathogenesis of multiple sclerosis, but the mechanisms that guide B cell activation in the periphery and subsequent migration to the CNS remain incompletely understood. We previously showed that systemic inflammati
Publikováno v:
BioScience Trends. 15:240-248
Circulating inflammatory factors affect osteoblast and osteoclast formation and activity in osteoporosis. Estrogen affects the migration of Th17 cells via the C-C chemokine receptor type 6 (CCR6) and C-C chemokine ligand 20 (CCL20) signaling pathways
Autor:
Danilo Candido de Almeida, Carla Longo de Freitas, Carolina Manganeli Polonio, Silvio Halpern, P.M. Perin, Mariangela Maluf, Lucila Evangelista, Jean Pierre Schatzmman Peron, Marília Garcia de Oliveira, Wesley Nogueira Brandão, Cristiano Rossato, Nágela Ghabdan Zanluqui, Lilian Gomes de Oliveira, Carlos Eduardo Czresnia
Publikováno v:
Stem Cell Reviews and Reports. 18:609-625
Mesenchymal stem cells comprise a natural reservoir of undifferentiated cells within adult tissues. Given their self-renewal, multipotency, regenerative potential and immunomodulatory properties, MSCs have been reported as a promising cell therapy fo
Autor:
Ismael Mancilla-Herrera, Mextli Y. Bermejo‐Haro, Sandra Rodríguez-Martínez, Gabriela González‐Pérez, Ricardo Figueroa-Damián, Gabriela Arreola‐Ramírez, Rodrigo T. Camacho‐Pacheco, Claudia Sandoval-Montes, Irma A. Coronado-Zarco, Alma Herrera-Salazar, Diana Mercedes Soriano-Becerril, Noemi Plazola-Camacho, Yesenia Brito‐Pérez, Jessica Hernández-Pineda, Julio C Flores-González, Brenda G. Casorla‐Cervantes, Ismael A. Soto‐López
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1541-1553 (2021)
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease
Introduction HIV‐exposed uninfected (HEU) newborns suffer from higher risks of opportunistic infections during the first months of life compared to HIV‐unexposed uninfected (HUU) newborns. Alterations in thymic mass, amounts of T helper (Th) cell
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:3289-3298
Aging is closely related to the occurrence of many diseases, including cancer, and involves changes in the immune microenvironment. γδT cells are important components of resident lymphocytes in mucosal tissues. However, little is known about the ef
Publikováno v:
Journal of Orthopaedic Research. 40:1213-1222
The involvement of intervertebral disc (IVD) tissues, whole blood (WB) cytokines, and chemokines in pain in patients with lumbar degenerative disc disease (LDD) is unknown. We investigated the relationships between inflammatory cytokines and chemokin
Autor:
Gracia Montero-Peñalvo, Fé Isabel García-Maceira, Isaac Túnez-Fiñana, Elier Paz-Rojas, Verónica Luna-Guerrero, Sara Gómez-Melero, Tania García-Maceira
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Biotechnology
BMC Biotechnology
Background CCR6 chemokine receptor is an important target in inflammatory diseases. Th17 cells express CCR6 and a number of inflammatory cytokines, including IL-17 and IL-22, which are involved in the propagation of inflammatory immune responses. CCR