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Akademický článek

Development of a traditional Chinese medicine‐based agent for the treatment of cancer cachexia

Autor: Kun‐Chang Wu, Po‐Chen Chu, Yu‐Jung Cheng, Chia‐Ing Li, Jingkui Tian, Hsing‐Yu Wu, Szu‐Hsien Wu, Yi‐Chun Lai, Hsiang‐Han Kao, Ao‐Lin Hsu, Hsiang‐Wen Lin, Chih‐Hsueh Lin

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2073-2087 (2022)

Abstract Background Despite recent advances in understanding the pathophysiology of cancer cachexia, prevention/treatment of this debilitating disease remains an unmet medical need. Methods We developed an integrated, multi‐tiered strategy involvin

Externí odkaz: https://doaj.org/article/e52515a1b0c4493788a292f72d4c7817

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Akademický článek

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Higher tumor mass and lower adipose mass are associated with colon-26 adenocarcinoma-induced cachexia in male, female and ovariectomized mice

Autor: Austin Angelotti, Martha A. Belury, Rachel M. Cole, Deena Snoke, Taylor Banh, Patrick Schnell

Publikováno v: Oncology Reports

Cachexia is responsible for nearly 20% of all cancer‑related deaths, yet effective therapies to prevent or treat the disease are lacking. Clinical studies have shown that male patients lose weight at a faster rate than females. Additionally, an 'ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3455235654fd4f95b9d89449d99df5
http://europepmc.org/articles/PMC6448095

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Akademický článek

New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles

Autor: Atefeh Hekmat, Hossein Attar, Ali Akbar Seyf Kordi, Maryam Iman, Mahmoud Reza Jaafari

Publikováno v: Molecules, Vol 21, Iss 9, p 1265 (2016)

Intravenous administration of Taxotere® (a commercial form of docetaxel, DTX) leads to many problems such as hypersensitivity, hemolysis, cutaneous allergy, and patient refusal due to its prolonged injection. The oral absorption of DTX is very low d

Externí odkaz: https://doaj.org/article/fb0242d18b294ab4877cb28fbd9f53fe

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Akademický článek

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Dissertation/ Thesis

Naringenin Attenuates Metabolic Disturbances in C-26 Cancer Cachexia Mouse Model: Transitional Study for Human Application

Autor: Nishikawa, Yuko

Cancer cachexia is a wasting disease which leads to poor disease prognosis and survival. Cachexia affects about 80% of advanced cancer patients and causes up to one-third of all cancer-related deaths. To date, effective treatment that directly target

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=osu1563983598733999

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Dissertation/ Thesis

Exploration of Adipose in the Pathogenesis of Cancer Cachexia

Autor: Banh, Taylor

Cancer cachexia is a systemic disease characterized by loss of adipose and muscle mass that contributes to poor quality of life while hastening mortality. Several clinical studies suggest that adipose loss occurs before muscle loss in patients with c

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=osu1532520752821935

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Akademický článek

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New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles

Autor: Hossein Attar, Mahmoud Reza Jaafari, Atefeh Hekmat, Maryam Iman, Ali Akbar Seyf Kordi

Publikováno v: Molecules, Vol 21, Iss 9, p 1265 (2016)
Molecules; Volume 21; Issue 9; Pages: 1265
Molecules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b625ed0cd6ddeeab15822ffb53dfd6
http://www.mdpi.com/1420-3049/21/9/1265

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