Novel Pheochromocytoma Susceptibility Loci Identified by Integrative Genomics

Autor: Danielle Magoffin, Alberto Cascón, Neil Aronin, Christian Colin, Ke Hao, Sergio P. A. Toledo, Patricia L. M. Dahia, Charles D. Stiles, John Rogus, C Y Hayashida, Kenneth N. Ross, Miguel A.G. Pujana, Cheng Li

Publikováno v: Cancer Research. 65:9651-9658

Pheochromocytomas are catecholamine-secreting tumors that result from mutations of at least six different genes as components of distinct autosomal dominant disorders. However, there remain familial occurrences of pheochromocytoma without a known gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d1f5fb3bacde14dffc0e22170607fc
https://doi.org/10.1158/0008-5472.can-05-1427

Impaired Adrenocorticotropin-Adrenal Axis in Combined Pituitary Hormone Deficiency Caused by a Two-Base Pair Deletion (301–302delAG) in the Prophet of Pit-1 Gene1

Autor: Joy D. Cogan, Vyacheslav V. Vasilyev, Pamela L. Mellon, Delmar M. Lourenço, C Y Hayashida, Carmela Ferrari, Sergio P. A. Toledo, Flavia Pernasetti

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 85:390-397

The Prophet of Pit-1 gene (PROP1) encodes a paired-like homeodomain protein, which is expressed early in pituitary gland development. When mutated, it is responsible for combined pituitary hormone deficiency (CPHD) in humans, as well as in Ames dwarf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::adb70b7aa62d616c6c2f528899431f50
https://doi.org/10.1210/jcem.85.1.6324

Familial Dwarfism due to a Novel Mutation of the Growth Hormone-Releasing Hormone Receptor Gene1

Autor: Rogério G. Gondo, Sergio P. A. Toledo, Gerhard Baumann, Manuel H. Aguiar-Oliveira, C Y Hayashida, Hiralal G. Maheshwari, Michael A. Levine, Maria M. Conceicão, Melissa A. Prince, John A. Phillips, Roberto Salvatori, Anita H. O. Souza

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:917-923

Isolated growth hormone (GH) deficiency (IGHD) is a rare cause of short stature. The same mutation of the gene encoding the growth hormone-releasing hormone receptor (GHRHR) has been identified as the basis for IGHD in three families from the Indian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1be72011d652d12f0c0fe83fcb805af
https://doi.org/10.1210/jcem.84.3.5599

Oxidative stress and modification of renal vascular permeability are associated with acute kidney injury during P. berghei ANKA infection

Autor: Meire Ioshie Hyane, Reinaldo Correia Silva, Renato Barboza, Claudio Romero Farias Marinho, Rosa Maria Elias, Marlene Antônia dos Reis, Tarcio Teodoro Braga, Niels Olsen Saraiva Câmara, Antônio Martins Figueiredo-Neto, Alvaro Pacheco-Silva, Ângela Castoldi, Matheus Correa-Costa, Giselle Martins Gonçalves, Claudiene Rodrigues Barreto, Francisco J. Rios, C. Y. Hayashida, Maria Regina D'Império-Lima, Marcos Antonio Cenedeze, Alexandre C. Keller

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e44004 (2012)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE

Malaria associated-acute kidney injury (AKI) is associated with 45% of mortality in adult patients hospitalized with severe form of the disease. However, the causes that lead to a framework of malaria-associated AKI are still poorly characterized. So

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2b0510481986adffdf55356e5b5378
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22952850/?tool=EBI

Pivotal role of toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis

Autor: Rosa Maria Elias, Giselle Martins Gonçalves, Meire Ioshie Hyane, Alvaro Pacheco-Silva, Claudiene Rodrigues Barreto, Niels Olsen Saraiva Camara, Luiz Roberto Grassmann Bechara, Patricia Semedo, Matheus Correa-Costa, Patricia Chakur Brum, C. Y. Hayashida, Clarice Kazue Fujihara, Claudia Silva-Cunha, Dario S. Zamboni, Tarcio Teodoro Braga, Roberto Zatz

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 6, Iss 12, p e29004 (2011)
PLoS ONE

Tubule-interstitial nephritis (TIN) results in decreased renal function and interstitial inflammation, which ultimately leads to fibrosis. Excessive adenine intake can cause TIN because xanthine dehydrogenase (XDH) can convert this purine into an ins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd86fb606f6360a60a5761627ecf755