Zobrazeno 1 - 10
of 7 038
pro vyhledávání: '"C Y Chang"'
Autor:
Gaspard Pardon, Alison S. Vander Roest, Orlando Chirikian, Foster Birnbaum, Henry Lewis, Erica A. Castillo, Robin Wilson, Aleksandra K. Denisin, Cheavar A. Blair, Colin Holbrook, Kassie Koleckar, Alex C. Y. Chang, Helen M. Blau, Beth L. Pruitt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are powerful in vitro models to study the mechanisms underlying cardiomyopathies and cardiotoxicity. Quantification of the contractile function in single hiPSC-CMs
Externí odkaz:
https://doaj.org/article/1069e53e6dc340f895ccdf08770ab256
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1301 (2024)
Aging is the major risk factor for Alzheimer’s disease (AD). In the aged brain, myelin debris accumulates and is cleared by microglia. Phagocytosed myelin debris increases neutral lipid droplet content in microglia. Neutral lipids include cholester
Externí odkaz:
https://doaj.org/article/32701db5d5364177b9c55ea871b58c3a
Publikováno v:
Metalurgija, Vol 63, Iss 3-4, Pp 451-453 (2024)
The thickness of a metal-immersed carbon slide mounted on a train’s flow shoe was measured by using machine vision and deep learning. A method for measuring the thickness of carbon slide plate based on improved U2-Net is proposed. Aiming at the pro
Externí odkaz:
https://doaj.org/article/3bc8a8433c89486dbc73809b82569d24
Autor:
Tengfei Wang, Shuxiang Shi, Yuanyuan Shi, Peipei Jiang, Ganlu Hu, Qinying Ye, Zhan Shi, Kexin Yu, Chenguang Wang, Guoping Fan, Suwen Zhao, Hanhui Ma, Alex C. Y. Chang, Zhi Li, Qian Bian, Chao-Po Lin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Chemicals or drugs can accumulate within biomolecular condensates formed through phase separation in cells. Here, we use super-resolution imaging to search for chemicals that induce phase transition within chromatin at the microscale. This m
Externí odkaz:
https://doaj.org/article/3515f8cbf8e5467ab24066c5ddff6073
Autor:
Junghoon Lee, Adrianna L. De La Torre, Felix L. Rawlinson, Dylan B. Ness, Lionel D. Lewis, William F. Hickey, Catherine C. Y. Chang, Ta Yuan Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9151 (2024)
Cholesterol homeostasis is pivotal for cellular function. Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1), also abbreviated as SOAT1, is an enzyme responsible for catalyzing the storage of excess cholesterol to cholesteryl esters. ACAT1 is an e
Externí odkaz:
https://doaj.org/article/0cdf9d54a6cb449a8a13d8b0b47dd0ae
Autor:
G. M. Marques, N. Loose, E. Yankovsky, J. M. Steinberg, C.-Y. Chang, N. Bhamidipati, A. Adcroft, B. Fox-Kemper, S. M. Griffies, R. W. Hallberg, M. F. Jansen, H. Khatri, L. Zanna
Publikováno v:
Geoscientific Model Development, Vol 15, Pp 6567-6579 (2022)
We describe an idealized primitive-equation model for studying mesoscale turbulence and leverage a hierarchy of grid resolutions to make eddy-resolving calculations on the finest grids more affordable. The model has intermediate complexity, incorpora
Externí odkaz:
https://doaj.org/article/0b6cc516d96d455a8ead7186d552a308
Publikováno v:
International Journal of Infectious Diseases, Vol 134, Iss , Pp S9- (2023)
Intro: Foot hand mouth disease, which is caused by enteroviruses infection, is an epidemic disease in young children in East Asia. In general, it is a mild disease but lacks specific therapeutic drugs or effective treatment. Moreover, patients who ar
Externí odkaz:
https://doaj.org/article/b1a3096a9b6b4c5c8bcb252e1186d102
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Duchenne muscular dystrophy (DMD) is a progressive genetic myopathy that leads to heart failure from dilated cardiomyopathy by early adulthood. Recent evidence suggests that tamoxifen, a selective estrogen receptor modulator widely used to t
Externí odkaz:
https://doaj.org/article/bcc03fc6d7194bfeb4c491a1753444ab
Publikováno v:
Sensors, Vol 23, Iss 21, p 8710 (2023)
Smart agriculture utilizes Internet of Things (IoT) technologies to enable low-cost electrical conductivity (EC) sensors to support farming intelligence. Due to aging and changes in weather and soil conditions, EC sensors are prone to long-term drift
Externí odkaz:
https://doaj.org/article/4b59eab3f0f747c3b2f0caf0b78b2177
Autor:
Ta Yuan Chang, Catherine C. Y. Chang, Taylor C. Harned, Adrianna L. De La Torre, Junghoon Lee, Thao N. Huynh, James G. Gow
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 1, Iss 3, Pp 173-184 (2021)
Cholesterol serves as an essential lipid molecule in various membrane organelles of mammalian cells. The metabolites of cholesterol also play important functions. Acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1), also named as sterol O-acyltran
Externí odkaz:
https://doaj.org/article/a718787065e249078cafd7c261450165