Zobrazeno 1 - 10
of 58
pro vyhledávání: '"C Wunrau"'
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 133:1737-1741
Autor:
Katja Neugebauer, Susanne Fuchs-Winkelmann, Adrian Skwara, Berno Dankbar, Carsten O. Tibesku, Thomas Pap, C Wunrau
Publikováno v:
Journal of Orthopaedic Research. 25:569-577
In osteoarthritis (OA), hepatocyte growth factor (HGF) is supposed to play a role in cartilage repair. Because the development of osteophytes is a major characteristic of OA and thought to be part of an attempted repair process, the purpose of this s
Autor:
Thomas Pap, Guenter Steiner, Hans P. Kiener, Denise Beckmann, Josef S Smolen, J Holinka, Birgit Niederreiter, Ruth A. Byrne, Axel Wanivenhaus, C Wunrau, Clemens Scheinecker, K Dalwigk, Thomas Karonitsch
Publikováno v:
Annals of the Rheumatic Diseases. 75:A57.2-A57
While evidence implicates both the adaptive and innate immune system in rheumatoid arthritis (RA) pathogenesis, accumulating data indicate that the synovial tissue itself actively participates in the destructive inflammatory process. Specifically, re
Autor:
C Wunrau, Berno Dankbar, Katharina Freyth, Thomas Pap, Eva-Maria Schnaeker, Katja Neugebauer, Uwe Hansen, Doreen Wendholt, Noreen Pundt
Publikováno v:
Arthritis and rheumatism. 60(9)
Objective Synovial fibroblasts (SFs) contribute to several aspects of the pathogenesis of rheumatoid arthritis (RA) and have been implicated most prominently in the progressive destruction of articular cartilage. Targeting the invasive phenotype of R
Publikováno v:
Deutsche medizinische Wochenschrift (1946). 133(34-35)
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease of unknown aetiology that is characterized by the progressive destruction of articular structures. The accumulation of inflammatory cells in the joint and the transformation of
Publikováno v:
Annals of the Rheumatic Diseases. 70:A75-A76
Rheumatoid arthritis (RA) is the prototype for an inflammatory arthritis, characterised by chronic inflammation and progressive joint destruction. In this context, tumour necrosis factor α (TNFα) is a key cytokine in promoting destruction of bone b
Autor:
Athanasios Stratis, Thomas Pap, C Wunrau, N Pundt, K Neugebauer, Frank Echtermeyer, George Kollias, Corinna Wehmeyer
Publikováno v:
Annals of the Rheumatic Diseases. 69:A45-A46
Syndecan-4 is a transmembrane heparansulfate proteoglycan and one out of four members of the syndecan family described in mammals. Several studies have implicated syndecan-4 in cell-matrix adhesion, cell migration, differentiation and proliferation,
Autor:
Viktor Wixler, Thomas Pap, Lars Meyer, Jessica Bertrand, R Basel-Duby, C Will, E M Schnaeker, George Kollias, Kurt Redlich, C Cromme, K Neugebauer, Birgit Niederreiter, Adelheid Korb, D Beaten, C Wunrau
Publikováno v:
Annals of the Rheumatic Diseases. 69:A19-A20
Four-and-a-half LIM 2 (FHL2) is a mediator of protein interactions involved in cellular processes that are of relevance for the activation of mesenchymal cells. It interacts with integrins, focal adhesion-and mitogen-activated kinases, transcription
Autor:
H Pavenstädt, Dietmar Vestweber, Marianne Heitzmann, George Kollias, Adelheid Korb-Pap, Thomas Pap, Stefan Butz, C Wunrau
Publikováno v:
Annals of the Rheumatic Diseases. 71:487.3-487
Background Recent studies demonstrated the potential of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) to emigrate from affected joints and migrate via the bloodstream toward distant healthy cartilage in the SCID mouse model of disease. W
Autor:
Thomas Pap, Martin Böttcher, I Irmler, C Wunrau, Georg Schett, Thomas Kamradt, Adelheid Korb-Pap
Publikováno v:
Annals of the Rheumatic Diseases. 72:A10.2-A10
Purpose/Objective Immunizstion with Glucose-6-phosphate isomerase (G6PI) induces arthritis in susceptible strains of mice. Depletion of regulatory T cells (Tregs) prior to immunisation switches the usually acute, self-limiting course to a non-remitti