Zobrazeno 1 - 10
of 329
pro vyhledávání: '"C Wayne McIlwraith"'
Autor:
J Lacy Kamm, Natalie A Parlane, Christopher B Riley, Erica K Gee, Keren E Dittmer, C Wayne McIlwraith
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225161 (2019)
BackgroundAs the search for an immune privileged allogeneic donor mesenchymal stem cell (MSC) line continues in equine medicine, the characterization of the cells between different sources becomes important. Our research seeks to more clearly define
Externí odkaz:
https://doaj.org/article/a9d510c142044aa7b4d8197f571b408f
Autor:
Karla eLombana, Laurie R Goodrich, Jennifer Nikki Phillips, John David Kisiday, Audrey eRuple-Czerniak, C Wayne McIlwraith
Publikováno v:
Frontiers in Veterinary Science, Vol 2 (2015)
Diseases of the musculoskeletal system are a major cause of loss of use and retirement in sport horses. The use of bone marrow derived mesenchymal stem cells (BMDMSCs) for healing of traumatized tissue has gained substantial favor in clinical setting
Externí odkaz:
https://doaj.org/article/3cf1ade283e4469f91afd5182543069c
Autor:
Alessandro Bensa, Manuela Salerno, Giacomo Moraca, Angelo Boffa, C. Wayne McIlwraith, Giuseppe Filardo
Publikováno v:
Journal of Experimental Orthopaedics, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Purpose The purpose of this study was to quantify and compare the clinical relevance of the different intra‐articular corticosteroids (CS) effects in vivo for osteoarthritis (OA) treatment. Methods The search was conducted on PubMed, Cochr
Externí odkaz:
https://doaj.org/article/d91578d3012b4a1680403334987e200e
Autor:
Laurie R Goodrich, Jennifer N Phillips, C Wayne McIlwraith, Stacey B Foti, Joshua C Grieger, Steven J Gray, R Jude Samulski
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Osteoarthritis (OA) affects over 40 million people annually. We evaluated interleukin-1 receptor antagonist (IL-1ra) gene transfer in an equine model based on IL-1ra protein therapy which inhibits inflammation through blocking IL-1. Using the self-co
Externí odkaz:
https://doaj.org/article/37ec94c02cc0465d9a142c8a9067e082
Autor:
Luca Panizzi, Matthieu Vignes, Keren E. Dittmer, Mark R. Waterland, Chris W. Rogers, Hiroki Sano, C. Wayne McIlwraith, Christopher B. Riley
Publikováno v:
Animals, Vol 14, Iss 7, p 986 (2024)
Osteoarthritis is a leading cause of lameness and joint disease in horses. A simple, economical, and accurate diagnostic test is required for routine screening for OA. This study aimed to evaluate infrared (IR)-based synovial fluid biomarker profilin
Externí odkaz:
https://doaj.org/article/ab064299f11b4de9ab034541f62884ab
Autor:
Luca Panizzi, Keren E. Dittmer, Matthieu Vignes, Jennie S. Doucet, Kristene Gedye, Mark R. Waterland, Chris W. Rogers, Hiroki Sano, C. Wayne McIlwraith, Christopher B. Riley
Publikováno v:
Animals, Vol 13, Iss 6, p 1053 (2023)
Biomarkers for osteoarthritis (OA) in horses have been extensively investigated, but translation into clinical use has been limited due to cost, limited sensitivity, and practicality. Identifying novel biomarkers that overcome these limitations could
Externí odkaz:
https://doaj.org/article/a28e106af24145bbaf53e35f07ed2a14
Autor:
Lindsay E. Knott, B. Alexander Fonseca‐Martinez, Annette M. O'Connor, Laurie R. Goodrich, C. Wayne McIlwraith, Aimee C. Colbath
Publikováno v:
Veterinary Surgery. 51:557-567
To evaluate the use of mesenchymal stem cells (MSCs), autologous conditioned serum (ACS), platelet-rich plasma (PRP), and autologous protein solution (APS) for the treatment of equine musculoskeletal disease by diplomates of the American College of V
Autor:
Parvathy Thampi, R. Jude Samulski, Joshua C. Grieger, Jennifer N. Phillips, C. Wayne McIlwraith, Laurie R. Goodrich
Publikováno v:
Frontiers in Veterinary Science. 9
Autor:
Parvathy Thampi, Michel P. Laurent, Suzanne M Tabbaa, Marcus A Wimmer, David D. Frisbie, C. Wayne McIlwraith, Brian Johnstone
Publikováno v:
Journal of Orthopaedic Research. 40:1349-1357
The equine model of posttraumatic osteoarthritis (OA) mimics certain aspects of the naturally occurring disease, both in horses and humans. The objective of this study was to assess articular cartilage degeneration in a posttraumatic OA model using t
Autor:
John D. Kisiday, Christopher J. Centeno, Neven J. Steinmetz, Dustin R. Berger, C. Wayne McIlwraith
Publikováno v:
The American Journal of Sports Medicine. 49:3404-3413
Background: Umbilical cord (UC) connective tissues contain plastic-adherent, colony forming unit–fibroblasts (CFU-Fs) amenable to culture expansion for potential therapeutic use. Recently, UC-derived allograft products have been made available to p