Zobrazeno 1 - 10
of 48
pro vyhledávání: '"C Wade Downey"'
Publikováno v:
The Journal of Organic Chemistry. 86:17328-17336
N-Alkylindoles undergo Friedel-Crafts addition to aryl and secondary alkyl nitrones in the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine to produce 3-(1-(silyloxyamino)alkyl)indoles. Spontaneous conversion to bisindolyl(aryl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d98b4b2e50ac7c963589ea6eb3c734
https://doi.org/10.1021/acs.joc.1c01551
https://doi.org/10.1021/acs.joc.1c01551
Publikováno v:
The Journal of organic chemistry. 87(21)
In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and 2,6-lutidine, α,α-disubstituted aldehydes condense with electron-rich aromatic aldehydes to yield β,β-disubstituted styrenes. More electron-rich aromatic aldehydes react mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8465bea1a8a5b288c65881c3fa1d351
https://pubmed.ncbi.nlm.nih.gov/36239694
https://pubmed.ncbi.nlm.nih.gov/36239694
Autor:
C. Wade Downey, Elizabeth D. Heafner, Xuechun Lin, Alexa H. Connors, Hanyu Zhong, R. Joseph Coyle, Yiqi Liu
Publikováno v:
Synthesis.
Ketones and related substrate classes undergo enol silane formation in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and triethylamine, reaction conditions that also promote the in situ ionization of allyl propionates. When these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b8790f19f21bf4d49b8d7a257f12f8f
https://doi.org/10.1055/a-1959-2505
https://doi.org/10.1055/a-1959-2505
Publikováno v:
Tetrahedron Letters. 59:3080-3083
Aryl alkyl ketones, acetate esters, and acetamides undergo facile one-pot enol silane formation, Mukaiyama aldol addition, and dehydrosilyloxylation in the presence of an amine base and excess trimethylsilyl trifluoromethanesulfonate. The chalcone an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3a0ea356b718d1d17871be640c6f576
https://doi.org/10.1016/j.tetlet.2018.06.066
https://doi.org/10.1016/j.tetlet.2018.06.066
Publikováno v:
Tetrahedron Letters. 87:153424
In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and triethylamine, 3-(trimethylsilyl)propargyl carboxylates undergo a one-pot alkylation-cyclization-desilylation reaction with ketones to produce 2-methylfurans. Alkylation at 0 °
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75723567fe0db32016a5da227579fa5b
https://doi.org/10.1016/j.tetlet.2021.153424
https://doi.org/10.1016/j.tetlet.2021.153424
Publikováno v:
Tetrahedron Letters. 58:3496-3499
(Trimethylsilyl)acetonitrile reacts smoothly with dimethyl acetals in the presence of stoichiometric trimethylsilyl trifluoromethanesulfonate (TMSOTf) to yield β-methoxynitriles. The ideal substrates for this reaction are acetals derived from aromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c311b3b2a5984edc5fac1d5523eabc2a
https://doi.org/10.1016/j.tetlet.2017.07.082
https://doi.org/10.1016/j.tetlet.2017.07.082
Publikováno v:
Tetrahedron Letters. 61:152669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c679c9434dfb2a98a4c20d838ff5716d
https://doi.org/10.1016/j.tetlet.2020.152669
https://doi.org/10.1016/j.tetlet.2020.152669
Publikováno v:
Tetrahedron Letters. 61:151537
Trimethylsilyl trifluoromethanesulfonate (TMSOTf) and a trialkylamine base promote the conversion of acetonitrile to its silyl ketene imine in situ when acetonitrile is employed as solvent. Residual TMSOTf acts as a Lewis acid catalyst to activate ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d42756b44950a077a20824a98bfe5d3
https://doi.org/10.1016/j.tetlet.2019.151537
https://doi.org/10.1016/j.tetlet.2019.151537
Publikováno v:
The Journal of organic chemistry. 83(20)
Ketones readily undergo conversion to enol silanes in the presence of a trialkylamine base and trimethylsilyl trifluoromethanesulfonate (TMSOTf) and add to propargyl cations to yield β-alkynyl ketones. The propargyl cations are generated in the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803cbbf75c3f963acb1ba84d44e89f07
https://pubmed.ncbi.nlm.nih.gov/30248260
https://pubmed.ncbi.nlm.nih.gov/30248260
Autor:
C. Wade Downey, Carolyn M. Dombrowski, Hadleigh M. Glist, Jared A. Ingersoll, Adam T. Barnett
Publikováno v:
European Journal of Organic Chemistry. 2015:7287-7291
In the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base, thioesters are readily converted into silyl ketene acetals in situ and undergo Mukaiyama–Mannich addition to N-phenylimines in one pot. The silyl triflate appears t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2607eed364893fa2161ec35d85f5de08
https://doi.org/10.1002/ejoc.201500958
https://doi.org/10.1002/ejoc.201500958