Zobrazeno 1 - 10 of 27 pro vyhledávání: '"C W Riggs"'
2
Inhibition of vascular endothelial growth factor-induced endothelial cell migration by ETS1 antisense oligonucleotides
Autor: Z, Chen, R J, Fisher, C W, Riggs, J S, Rhim, J A, Lautenberger
Publikováno v: Cancer research. 57(10)
Vascular endothelial growth factor (VEGF) increased the level of ETS1 mRNA in human umbilical vein endothelial cells (HUVEC) and human lung microvascular endothelial cells (HMVEC-L) over 5-fold. Protein levels were shown to increase concordantly. VEG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::758ffc9b3fa4b3d26318a569486d446d
https://pubmed.ncbi.nlm.nih.gov/9157999
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3
Ahr locus phenotype in congenic mice influences hepatic and pulmonary DNA adduct levels of 2-amino-3-methylimidazo[4,5-f]quinoline in the absence of cytochrome P450 induction
Autor: P V, Nerurkar, H A, Schut, L M, Anderson, C W, Riggs, L W, Fornwald, C D, Davis, E G, Snyderwine, S S, Thorgeirsson, W W, Weber, J M, Rice, G N, Levy
Publikováno v: Molecular pharmacology. 49(5)
The potent food mutagen/carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) undergoes metabolic N-hydroxylation by cytochromes P450, including cytochrome P450 1A2, followed by generation of an unstable ester catalyzed by acetyltransferases; promu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10d846b8ce6e0235c266dc0bdc41ef04
https://pubmed.ncbi.nlm.nih.gov/8622637
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4
DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in colon, bladder, and kidney of congenic mice differing in Ah responsiveness and N-acetyltransferase genotype
Autor: P V, Nerurkar, H A, Schut, L M, Anderson, C W, Riggs, E G, Snyderwine, S S, Thorgeirsson, W W, Weber, J M, Rice, G N, Levy
Publikováno v: Cancer research. 55(14)
Heterocyclic amines, suspected as cancer initiators, require metabolic activation to exert genotoxicity. The food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) undergoes activation via N-hydroxylation by cytochrome P450 1A2, followed by O-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ac0fb371772109db3f270895ca454f9
https://pubmed.ncbi.nlm.nih.gov/7606725
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5
Selective retention of polychlorinated biphenyl congeners in lung and liver after single-dose exposure of infant mice to Aroclor 1254
Autor: L M, Anderson, S D, Fox, C W, Riggs, H J, Issaq
Publikováno v: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 12(1)
Infant male Swiss mice (8 days old) were given a single i.p. injection of 500 mg/kg of the polychlorinated biphenyl (PCB) mixture, Aroclor 1254, a treatment found in previous studies to result in promotion of nitrosamine-initiated lung and liver tumo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1af0dc8372b66241fe020d169f4ca67
https://pubmed.ncbi.nlm.nih.gov/8459365
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6
Enhanced therapeutic efficacy against an ovarian tumor xenograft of immunotoxins used in conjunction with recombinant alpha-interferon
Autor: J W, Pearson, E, Hedrick, W E, Fogler, R L, Bull, D K, Ferris, C W, Riggs, R H, Wiltrout, G, Sivam, A C, Morgan, E, Groves
Publikováno v: Cancer research. 50(19)
The antitumor effects of two immunotoxins were evaluated in vitro and in vivo against the human ovarian carcinoma cell line, OVCAR-3. The immunotoxins used were composed of recombinant ricin A chain (rRTA) covalently attached to a monoclonal antibody
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::33023648ada6951546d16a8b72b6013b
https://pubmed.ncbi.nlm.nih.gov/2144790
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7
Effect of 12-O-tetradecanoylphorbol-13-acetate on colony formation and intercellular communication in a coculture system of JB6 clones
Autor: I, Yamadori, U I, Heine, S, Kenney, C W, Riggs, J M, Rice
Publikováno v: Cancer research. 50(17)
Disruption of intercellular communication (IC) by tumor promoters has been implicated as one of the major events in the promotion process. We studied the effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on IC in relation to colony formation (CF)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97c1e3b98a63a51799441acf2f3662cb
https://pubmed.ncbi.nlm.nih.gov/2386963
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8
Effect of 12-O-tetradecanoylphorbol-13-acetate on intercellular communication in various clones of mouse epidermal JB6 cells
Autor: H, Miki, I, Yamadori, U I, Heine, S, Kenney, C W, Riggs, J M, Rice
Publikováno v: Cancer research. 50(4)
We studied gap junctional intercellular communication (IC) in various clones of mouse epidermal JB6 cells and the effect of the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA) on such communication. JB6 clones used included nonpromotable,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d39991b39dbb207b2fa5ca7acef8830
https://pubmed.ncbi.nlm.nih.gov/2297776
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10
Large-scale production and concentration of infectious Epstein-Barr virus
Autor: L J Charmella, J F Rosensteel, C W Riggs, Frederick Klein, E A Hillman, R M Hummer
Publikováno v: Applied and Environmental Microbiology. 35:172-178
Infectious Epstein-Barr virus (EBV) was produced from suspension cultures of P3HR-1 cells. A protocol for the scaled-up production and concentration of the virus was developed. Virus from the culture fluid was concentrated by continuous-flow pelletiz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f196dd515578293712d45094b0082a9
https://doi.org/10.1128/aem.35.1.172-178.1978
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