Zobrazeno 1 - 10
of 26
pro vyhledávání: '"C W, Wharton"'
Publikováno v:
Laser Chemistry. 19:209-222
The serine proteinase mechanism has been studied using a wide range of techniques over many years and is now well understood in terms of the formal chemical changes that occur on the reaction pathway. At the atomic level our understanding is less sec
Publikováno v:
Analytical Biochemistry. 255:120-126
The accurate determination of very low concentrations of ATP is important in many areas of pure and applied biochemistry, particularly hygiene monitoring in the food industry. Two mathematical models have been used to show that a luciferase-linked AT
Publikováno v:
Laser Chemistry. 19:233-235
When a protein finds its native three-dimensional structure from the unstructured amino-acid chain various processes spanning a large time range are relevant. To understand the mechanism of protein folding one needs to cover the entire folding/ refol
Publikováno v:
Journal of molecular biology. 285(2)
The two classes of fructose-1,6-bisphosphate aldolase both catalyse the reversible cleavage of fructose 1,6-bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The Class I aldolases use Schiff base formation as part of their
Publikováno v:
Methods in enzymology. 291
Autor:
D G, Lidzey, N, Berovic, R S, Chittock, T D, Beynon, C W, Wharton, J B, Jackson, N S, Parkinson
Publikováno v:
Radiation research. 143(2)
Measurements are presented of the radiation inactivation of four enzymes exposed to a 6 MeV proton beam. It has long been thought that the measurement of the susceptibility of an enzyme to ionizing radiation can be used to determine its molecular mas
Publikováno v:
Spectroscopy of Biological Molecules ISBN: 9789401041669
Thrombin has been extensively studied due to its role in thrombosis and other diseases [1]. Thrombin inhibitors might prove to be effective antithrombotic drugs [2]. Knowledge of how thrombin inhibitors bind to thrombin allows the possibility of stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9dd9a519623049448bd0b69206a851b
https://doi.org/10.1007/978-94-011-0371-8_71
https://doi.org/10.1007/978-94-011-0371-8_71
Autor:
T. E. Regan, C. W. Wharton
Publikováno v:
Spectroscopy of Biological Molecules ISBN: 9789401041669
Chymotrypsin and its acyl intermediate have been extensively studied using both infrared and Raman spectroscopies. Throughout these studies relatively non-specific acylating groups have been used. This has been necessary to ensure that the acyl enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2eeb251bb840c1a8eda147d07295f6
https://doi.org/10.1007/978-94-011-0371-8_73
https://doi.org/10.1007/978-94-011-0371-8_73
Publikováno v:
Spectroscopy of Biological Molecules ISBN: 9789401041669
Chymotrypsin is a serine protease. It acts selectively to catalyses the hydrolysis of peptide bonds on the C-terminus side of aromatic residues, and will also catalyse hydrolysis of hydrophobic esters such as cinnamoyl imidazole. It is composed of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2b09300936d722ce354cfe9281a0ce
https://doi.org/10.1007/978-94-011-0371-8_68
https://doi.org/10.1007/978-94-011-0371-8_68
Autor:
Hiroyuki Daido, L. Dwivedi, A. P. Juna, Harry Shields, P. Fluck, R. A. Meldrum, Gregory J. Tallents, I. C. Edmond Turcu, Juan R. Maldonado, P. Trenda, Dimitri Batani, C. W. Wharton, David L. Stevens, Alan Michette, J. Krishnan, M. S. Schulz, T. Jenner, H. Goodson, Ian N. Ross
Publikováno v:
SPIE Proceedings.
At Rutherford Appleton Laboratory we developed a high repetition rate, picosecond, excimer laser system which generates a high temperature and density plasma source emitting approximately 200 mW (78 mW/sr) x ray average power at h(nu) approximately 1