Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C W, Shearman"'
Publikováno v:
The Journal of Immunology. 147:4366-4373
Completely humanized antibodies with specificity for the human alpha/beta TCR have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 CD regions and human EU framework regions were synthesized and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2608ad31f57bf59950df798b5c08b092
https://doi.org/10.4049/jimmunol.147.12.4366
https://doi.org/10.4049/jimmunol.147.12.4366
Publikováno v:
The Journal of Immunology. 146:928-935
Murine/human chimeric antibodies with specificity for the human TCR-alpha/beta have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 were isolated and inserted into mammalian expression vectors co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e67f74563ba68311eb004c0f89c9b9a
https://doi.org/10.4049/jimmunol.146.3.928
https://doi.org/10.4049/jimmunol.146.3.928
Publikováno v:
Diabetes care. 24(5)
Increased albumin excretion in diabetes is believed to be derived from hemodynamic and/or permeability abnormalities, whereas mesangial matrix expansion gives rise to the reduction in glomerular filtration surface and decline in renal function in dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::281e1efac50cc8193c237cc73f6c2fc9
https://pubmed.ncbi.nlm.nih.gov/11347754
https://pubmed.ncbi.nlm.nih.gov/11347754
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(12)
Completely humanized antibodies with specificity for the human alpha/beta TCR have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 CD regions and human EU framework regions were synthesized and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b5380b58cdbd154660e373e4c08d416
https://pubmed.ncbi.nlm.nih.gov/1836485
https://pubmed.ncbi.nlm.nih.gov/1836485
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(3)
Murine/human chimeric antibodies with specificity for the human TCR-alpha/beta have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 were isolated and inserted into mammalian expression vectors co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de139d81d3bc6877c5ff4cfe797faff4
https://pubmed.ncbi.nlm.nih.gov/1824850
https://pubmed.ncbi.nlm.nih.gov/1824850
Autor:
Y, Li, C W, Shearman
Publikováno v:
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 12(5)
A murine/human chimeric antibody with specificity for hepatitis B surface antigen has been produced by genetic engineering. The light and heavy chain variable region exons encoding the murine monoclonal antibody 2H1 were isolated and inserted into ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40166be461e6bca50ca8277b81f3d84f
https://pubmed.ncbi.nlm.nih.gov/2151688
https://pubmed.ncbi.nlm.nih.gov/2151688
Publikováno v:
Journal of Biological Chemistry. 254:5229-5237
The fidelity of DNA synthesis with purified DNA polymerase alpha and beta from human placenta has been studied. With poly[d(A-T)] as the template-primer and Mg2+ as the metal activator, DNA polymerase alpha incorporates 1 mol of dGMP for every 6,000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a9b62eed3f5f37d101c987901a82bb
https://doi.org/10.1016/s0021-9258(18)50583-4
https://doi.org/10.1016/s0021-9258(18)50583-4
Autor:
D. P. Rhodes, A. D. Barone, Tse Wen Chang, Nancy T. Chang, S. McKinney, C. W. Shearman, S. H. Tam, J. Huang, Flossie Wong-Staal, Robert C. Gallo, P. K. Chanda
Publikováno v:
Science. 228:93-96
Human T-cell lymphotropic virus type III (HTLV-III), the causative agent of the acquired immune deficiency syndrome (AIDS), was recently isolated and its genomic structure analyzed by DNA cloning methods. In the studies reported here a combined cloni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ebc842e1d13e9ecc335b047caa03c2
https://doi.org/10.1126/science.2983429
https://doi.org/10.1126/science.2983429
Publikováno v:
Journal of Biological Chemistry. 258:4485-4491
Two distinct mechanisms of action for intercalating agents have been delineated: one leading to the production of frameshift misincorporations and the other leading to the production of single-base substitutions. Addition misincorporations are compet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ba53e5bb7631110207500c8a7001f7
https://doi.org/10.1016/s0021-9258(18)32649-8
https://doi.org/10.1016/s0021-9258(18)32649-8
Publikováno v:
Cancer research. 40(7)
The effect of three environmentally important metals, arsenic, selenium, and chromium, on the accuracy of DNA synthesis in vitro has been analyzed. The addition of arsenic to fidelity assays did not significantly alter accuracy. Selenium did not alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::834f46c2d6e2722c2c82d88166e0f07d
https://pubmed.ncbi.nlm.nih.gov/6992986
https://pubmed.ncbi.nlm.nih.gov/6992986