Zobrazeno 1 - 10
of 27
pro vyhledávání: '"C W, RIGGS"'
Autor:
C W, RIGGS, A C, TEW
Publikováno v:
Journal of the American Veterinary Medical Association. 111(844)
Publikováno v:
Cancer research. 57(10)
Vascular endothelial growth factor (VEGF) increased the level of ETS1 mRNA in human umbilical vein endothelial cells (HUVEC) and human lung microvascular endothelial cells (HMVEC-L) over 5-fold. Protein levels were shown to increase concordantly. VEG
Autor:
P V, Nerurkar, H A, Schut, L M, Anderson, C W, Riggs, L W, Fornwald, C D, Davis, E G, Snyderwine, S S, Thorgeirsson, W W, Weber, J M, Rice, G N, Levy
Publikováno v:
Molecular pharmacology. 49(5)
The potent food mutagen/carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) undergoes metabolic N-hydroxylation by cytochromes P450, including cytochrome P450 1A2, followed by generation of an unstable ester catalyzed by acetyltransferases; promu
Autor:
P V, Nerurkar, H A, Schut, L M, Anderson, C W, Riggs, E G, Snyderwine, S S, Thorgeirsson, W W, Weber, J M, Rice, G N, Levy
Publikováno v:
Cancer research. 55(14)
Heterocyclic amines, suspected as cancer initiators, require metabolic activation to exert genotoxicity. The food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) undergoes activation via N-hydroxylation by cytochrome P450 1A2, followed by O-
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 12(1)
Infant male Swiss mice (8 days old) were given a single i.p. injection of 500 mg/kg of the polychlorinated biphenyl (PCB) mixture, Aroclor 1254, a treatment found in previous studies to result in promotion of nitrosamine-initiated lung and liver tumo
Autor:
J W, Pearson, E, Hedrick, W E, Fogler, R L, Bull, D K, Ferris, C W, Riggs, R H, Wiltrout, G, Sivam, A C, Morgan, E, Groves
Publikováno v:
Cancer research. 50(19)
The antitumor effects of two immunotoxins were evaluated in vitro and in vivo against the human ovarian carcinoma cell line, OVCAR-3. The immunotoxins used were composed of recombinant ricin A chain (rRTA) covalently attached to a monoclonal antibody
Publikováno v:
Cancer research. 50(17)
Disruption of intercellular communication (IC) by tumor promoters has been implicated as one of the major events in the promotion process. We studied the effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on IC in relation to colony formation (CF)
Publikováno v:
Cancer research. 50(4)
We studied gap junctional intercellular communication (IC) in various clones of mouse epidermal JB6 cells and the effect of the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA) on such communication. JB6 clones used included nonpromotable,
Autor:
Ofelia A. Olivero, B. A. Diwan, Miriam C. Poirier, C. W. Riggs, J. M. Rice, L. M. Anderson, S. H. Yuspa, T. J. Moskal, D. C. Haines, A. B. Jones
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 14:A29
Publikováno v:
Applied and Environmental Microbiology. 35:172-178
Infectious Epstein-Barr virus (EBV) was produced from suspension cultures of P3HR-1 cells. A protocol for the scaled-up production and concentration of the virus was developed. Virus from the culture fluid was concentrated by continuous-flow pelletiz