Zobrazeno 1 - 10
of 13
pro vyhledávání: '"C W, Heilig"'
Autor:
Y. C. Li, Youli Wang, Richard J. Quigg, Bradley K. Hack, Jessy J. Alexander, C. W. Heilig, Jian Zhou, Mark Haas, Andrew W. Minto
Publikováno v:
Kidney International. 70:882-891
The db/db mouse develops features of type II diabetes mellitus as the result of impaired signaling through its abnormal leptin receptor. In spite of accurate metabolic features of diabetes, renal disease manifestations in these mice are not as severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe39750d6724c3c648befe8d9808ed8b
https://doi.org/10.1038/sj.ki.5001624
https://doi.org/10.1038/sj.ki.5001624
Autor:
C. W. Heilig, Y. Liu, R. L. England, S. O. Freytag, J. D. Gilbert, K. O. Heilig, M. Zhu, L. A. Concepcion, F. C. Brosius
Publikováno v:
Diabetes. 46:1030-1039
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b3afce564450895e48dc32ccc4af93
https://doi.org/10.2337/diabetes.46.6.1030
https://doi.org/10.2337/diabetes.46.6.1030
Publikováno v:
Journal of Clinical Investigation. 96:1802-1814
An environment of high glucose concentration stimulates the synthesis of extracellular matrix (ECM) in mesangial cell (MC) cultures. This may result from a similar increase in intracellular glucose concentration. We theorized that increased uptake, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39039eb91a929dc6336e2c94e9cf5120
https://doi.org/10.1172/jci118226
https://doi.org/10.1172/jci118226
Publikováno v:
American Journal of Physiology-Renal Physiology. 259:F653-F659
MDCK cells accumulate organic osmolytes in response to hyperosmotic NaCl-supplemented medium. We examined time course and inhibitor sensitivity of myo-inositol, sorbitol, and glycerophosphorylcholine (GPC) accumulation in MDCK cells exposed to hypero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1431123aa112c24cac9b28d9c4473e01
https://doi.org/10.1152/ajprenal.1990.259.4.f653
https://doi.org/10.1152/ajprenal.1990.259.4.f653
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To test the hypothesis that pathophysiological levels of glucose regulate aldose reductase (AR2) gene expression, protein production, and activity in human retinal pigment epithelial (RPE) cells in vitro.Primary cultures of human RPE cells were grown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db23a6237ffdd1a3bebae5933116e801
https://pubmed.ncbi.nlm.nih.gov/10798676
https://pubmed.ncbi.nlm.nih.gov/10798676
Publikováno v:
Kidney international. Supplement. 60
Several glucose transporters have recently been identified in glomeruli, and in cultured glomerular cells. These include the facilitative glucose transporter isoforms GLUTs 1, 3 and 4, and sodium-glucose cotransport activity with characteristics of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::157dade294a1e554ef9e82ea92ec2c80
https://pubmed.ncbi.nlm.nih.gov/9285909
https://pubmed.ncbi.nlm.nih.gov/9285909
Publikováno v:
Seminars in nephrology. 14(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b26159fc39f3dc8c034fa46678a10fd
https://pubmed.ncbi.nlm.nih.gov/8140344
https://pubmed.ncbi.nlm.nih.gov/8140344
Publikováno v:
The American journal of physiology. 260(4 Pt 1)
Attempts to understand brain volume regulation have been greatly hampered by the structural complexity of the mammalian central nervous system, indicating a need for the investigation of cultured brain cell lines whose behavior reflects that observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406c0524ab3b2577643c56daaa2e73b6
https://pubmed.ncbi.nlm.nih.gov/2018110
https://pubmed.ncbi.nlm.nih.gov/2018110
Publikováno v:
Kidney and Blood Pressure Research. 12:191-201
Methylamines and polyols are known to behave as organic osmolytes in the adaptation of many cells to hyperosmolar conditions. Using 1H nuclear magnetic resonance spectroscopy to analyze perchloric acid extracts we have examined several tissues in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad57518feef2feaee04f9c7383085e32
https://doi.org/10.1159/000173193
https://doi.org/10.1159/000173193
Publikováno v:
American Journal of Physiology-Renal Physiology. 257:F1117-F1123
Methylamines and polyhydric alcohols (polyols) are major organic osmolytes of the mammalian renal inner medulla and have generally been noted to change in parallel with urine osmolality. In the present study, responses of inner medullary methylamines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a524d0595ea7f6aba0129a0d318fbd67
https://doi.org/10.1152/ajprenal.1989.257.6.f1117
https://doi.org/10.1152/ajprenal.1989.257.6.f1117