Výsledky vyhledávání - "C V Jongeneel"

Modeling sequencing errors by combining Hidden Markov models

Autor: Philipp Bucher, Claudio Lottaz, Christian Iseli, C. V. Jongeneel

Publikováno v: ECCB
Europe PubMed Central

Among the largest resources for biological sequence data is the large amount of expressed sequence tags (ESTs) available in public and proprietary databases. ESTs provide information on transcripts but for technical reasons they often contain sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36d4d725c7535f613367564c3e4de5b
https://doi.org/10.1093/bioinformatics/btg1067

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Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing

Autor: Christian Iseli, Gregory J. Riggins, Anita Lal, Richard Harris, C. V. Jongeneel, Andrew J. G. Simpson, Robert L. Strausberg, Anson W. Mackay, Brian Stevenson, Michael J. O'Hare, A. M. Neville

Publikováno v: Proceedings of the National Academy of Sciences. 100:4702-4705

Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in individual human cells and tissues. Here, we describe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0288ec6414075fc34535be835fb794
https://doi.org/10.1073/pnas.0831040100

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Genomic organization and chromosomal localization of the mouse lipopolysaccharide binding protein gene

Autor: Sylvain Lengacher, Darryl S. Reed, Didier Heumann, C. V. Jongeneel

Publikováno v: Immunogenetics. 49:553-556

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f70800bc1fe2582698fdd1e6504bd9
https://doi.org/10.1007/s002510050535

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Analysis of tumor necrosis factor promoter responses to ultraviolet light

Autor: Bruce Beutler, A Shakhov, Flavia Bazzoni, C. V. Jongeneel, Véronique Kruys

Publikováno v: Journal of Clinical Investigation. 93:56-62

Ultraviolet (UV) light induces the biosynthesis of chloramphenicol acetyltransferase (CAT) in the skin of mice bearing the CATTNF reporter transgene. Moreover, nuclear run-on assays indicate that UV light induces transcription of the TNF gene in RAW

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0220f6d07850733110ccac2db88981f4
https://doi.org/10.1172/jci116984

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A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors

Autor: Manuel C. Peitsch, C V Jongeneel

Publikováno v: International Immunology. 5:233-238

Based on the similarity in primary structure between the newly characterized ligand for CD40 (CD40L) and the tumor necrosis factors (TNFs), we have modeled a detailed 3-D structure for CD40L. We used the known structure of TNF alpha as a template for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f771162c7a16ae19802af07e5f1429f
https://doi.org/10.1093/intimm/5.2.233

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Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-alpha promoter in primary macrophages

Autor: C Drouet, A N Shakhov, C V Jongeneel

Publikováno v: The Journal of Immunology. 147:1694-1700

In macrophages, the TNF-alpha promoter is specifically induced by bacterial endotoxin, and provides a good model for gene regulation during bacterial infections. We have analyzed the protein-binding characteristics and enhancer activity of four kappa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db58df77780660eb6f73c9016b04bc2a
https://doi.org/10.4049/jimmunol.147.5.1694

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trans activation of the tumor necrosis factor alpha promoter by the human T-cell leukemia virus type I Tax1 protein

Autor: C. V. Jongeneel, A N Shakhov, Hugo Albrecht

Publikováno v: Journal of Virology. 66:6191-6193

In a cotransfection assay, the human T-cell leukemia virus type I Tax1 gene product specifically activated transcription from the mouse tumor necrosis factor alpha promoter. The activation patterns of 5' deletion mutants, artificial enhancer construc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d411aa61cd97e5ba9b1c07402ac9ecc6
https://doi.org/10.1128/jvi.66.10.6191-6193.1992

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Efficient adenoviral transfer of NF-kappaB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis

Autor: T R, Bakker, D, Reed, T, Renno, C V, Jongeneel

Publikováno v: International journal of cancer. 80(2)

It has been suggested that the in vitro cytotoxicity of tumor necrosis factor (TNF) toward a number of transformed cell lines could make it a useful agent for anti-tumor therapy. However, many tumor cell lines are resistant to TNF-induced cell death.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::527d522a72312ca7d0648b90d69b417e
https://pubmed.ncbi.nlm.nih.gov/9935217

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Construction and characterization of a recombinant adenovirus directing expression of the MAGE-1 tumor-specific antigen

Autor: D S, Reed, P, Romero, D, Rimoldi, J C, Cerottini, J, Schaack, C V, Jongeneel

Publikováno v: International journal of cancer. 72(6)

The finding that many human melanomas express distinct antigens that can be recognised by specific cytolytic T lymphocytes (CTL) implies that immunotherapeutic strategies against this cancer might prove effective. The ex vivo delivery of a tumour-ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7bdc5726393fa5ba509e6791fbe49bf7
https://pubmed.ncbi.nlm.nih.gov/9378539

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