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pro vyhledávání: '"C Twort"'
This new edition of a classic text has been significantly expanded to cover the most current issues and international standards are examined in-depth, with detailed coverage of WHO, European, UK and US standards, organisations and practice. Written w
Publikováno v:
British Journal of Pharmacology. 132:729-741
1. Airway smooth muscle (ASM) is a potential source of multiple pro-inflammatory cytokines during airway inflammation. beta-Adrenoceptor agonist hyporesponsiveness is a characteristic feature of asthma, and interleukin (IL)-1 beta and tumour necrosis
Autor:
Cecilia P. C. Soh, Stuart J John Hirst, Matthew P. Hallsworth, Tak H. Lee, Charles H. C. Twort
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 19:910-919
Airway smooth muscle may be an important cellular source of proinflammatory mediators and cytokines and may participate directly in airway inflammation. In this study we have examined whether airway smooth muscle cells could contribute to mechanisms
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 270:L415-L428
The effect of recombinant platelet-derived growth factor (PDGF) isoforms (PDGF-AA, -BB and -AB) on mitogenesis of human cultured airway smooth muscle (ASM) was examined using the MTT-reduction assay and [3H]thymidine incorporation. Results were corre
Publikováno v:
British Journal of Pharmacology. 115:1117-1125
1. K+ currents were studied in smooth muscle cells enzymatically dissociated from human bronchi, by use of the patch-clamp technique. 2. In whole-cell recordings a depolarization-induced, 4-aminopyridine (4-AP)-sensitive current was observed in only
Publikováno v:
British Journal of Pharmacology. 113:1237-1242
1. The involvement of protein kinase C (PKC) in constriction of small bronchioles has never been investigated. In this study we have examined the effects of the specific PKC inhibitors Ro31-8220 and Ro31-7549 and the non-specific inhibitor H7 on carb
Autor:
A. Warley, H. B. Cammish, S. J. Hirst, K. P. B. Cracknell, Charles H. C. Twort, Jeremy P.T. Ward
Publikováno v:
Journal of Microscopy. 175:143-153
Methods for growing and preparing smooth muscle cells, isolated from rabbit trachealis, for X-ray microanalysis studies are presented. The cells are grown on Pioloform-covered gold grids supported on Thermanox coverslips. This provides a growth-compa
Autor:
C. C. Twort, A. H. Baker
Publikováno v:
The Journal of hygiene. 43(6)
During the last year further investigations of germicidal mists, especially those produced by heat-volatilization of phenols, have been carried out. We are primarily interested in continuous disinfection of the air in the presence of man, and all our
Autor:
C. C. Twort
Publikováno v:
The Journal of hygiene. 23(3)
IN 1913, Fraenkel and Much1 inoculated monkeys, guinea-pigs, rabbits and dogs intraperitoneally with large quantities of material obtained from two cases of Lymphadenoma, no accompanying tubercular disease being demonstrable. The material was broken