Zobrazeno 1 - 10
of 87
pro vyhledávání: '"C Theo Verrips"'
Autor:
David Lutje Hulsik, Ying-ying Liu, Nika M Strokappe, Simone Battella, Mohamed El Khattabi, Laura E McCoy, Charles Sabin, Andreas Hinz, Miriam Hock, Pauline Macheboeuf, Alexandre M J J Bonvin, Johannes P M Langedijk, David Davis, Anna Forsman Quigley, Marlén M I Aasa-Chapman, Michael S Seaman, Alejandra Ramos, Pascal Poignard, Adrien Favier, Jean-Pierre Simorre, Robin A Weiss, C Theo Verrips, Winfried Weissenhorn, Lucy Rutten
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003202 (2013)
The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodie
Externí odkaz:
https://doaj.org/article/bedacc53dae644739bdc70b2ea981c66
Autor:
Milla Summanen, Niko Granqvist, Raimo K Tuominen, Marjo Yliperttula, C Theo Verrips, Johannes Boonstra, Christophe Blanchetot, Elina Ekokoski
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35630 (2012)
Dysregulation of PKCε is involved in several serious diseases such as cancer, type II diabetes and Alzheimer's disease. Therefore, specific activators and inhibitors of PKCε hold promise as future therapeutics, in addition to being useful in resear
Externí odkaz:
https://doaj.org/article/9b60389161564e70bffc909754728330
Autor:
Anna Hultberg, Nigel J Temperton, Valérie Rosseels, Mireille Koenders, Maria Gonzalez-Pajuelo, Bert Schepens, Lorena Itatí Ibañez, Peter Vanlandschoot, Joris Schillemans, Michael Saunders, Robin A Weiss, Xavier Saelens, José A Melero, C Theo Verrips, Steven Van Gucht, Hans J de Haard
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e17665 (2011)
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Vi
Externí odkaz:
https://doaj.org/article/be706cebe8694a689e58995df755499f
Autor:
Chris D Emmerson, Els J van der Vlist, Myrthe R Braam, Peter Vanlandschoot, Pascal Merchiers, Hans J W de Haard, C Theo Verrips, Paul M P van Bergen en Henegouwen, Edward Dolk
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26299 (2011)
The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day t
Externí odkaz:
https://doaj.org/article/47bd55659bc0464fa0a1c43a37e7cfc1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Epitope mapping using BMP heterodimers (BMP4/7, BMP2/6 and BMP2/7).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a79b48202f3b0898ee281ba858eac0
https://doi.org/10.1158/1535-7163.22501663
https://doi.org/10.1158/1535-7163.22501663
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Bone morphogenetic proteins (BMP) have important but distinct roles in tissue homeostasis and disease, including carcinogenesis and tumor progression. A large number of BMP inhibitors are available to study BMP function; however, as most of these ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d83c17fc91e5e3adde4774a0324064
https://doi.org/10.1158/1535-7163.c.6536857.v1
https://doi.org/10.1158/1535-7163.c.6536857.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Supplementary file containing Supplementary materials and methods, supplementary figure legends and supplementary references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404265aa745e8b042e9e9f3c4b08f87e
https://doi.org/10.1158/1535-7163.22501660.v1
https://doi.org/10.1158/1535-7163.22501660.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Summary of epitope binning experiments of the VHHs and controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d561ed6d3a9847aeff23646344834
https://doi.org/10.1158/1535-7163.22501657.v1
https://doi.org/10.1158/1535-7163.22501657.v1
Autor:
Robin A. Weiss, C. Theo Verrips
Publikováno v:
Vaccines, Vol 7, Iss 3, p 77 (2019)
Nanobodies or VHH (variable domains of heavy-chain only antibodies) are derived from camelid species such as llamas and camels. Nanobodies isolated and selected through phage display can neutralize a broad range of human immunodeficiency virus type 1
Externí odkaz:
https://doaj.org/article/6f3350587abf441a81b6adf7aff687bf
Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies
Autor:
Jord C, Stam, Steven, de Maat, Dorien, de Jong, Mathia, Arens, Fenna, van Lint, Lavina, Gharu, Mark H, van Roosmalen, Rob C, Roovers, Nika M, Strokappe, Ralf, Wagner, Alexander, Kliche, Hans J, de Haard, Paul M, van Bergen En Henegouwen, Monique, Nijhuis, C Theo, Verrips
Publikováno v:
Scientific reports. 12(1)
While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patients with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc6bf3265c831cf2f5df2dde14c3791e
https://pubmed.ncbi.nlm.nih.gov/35927444
https://pubmed.ncbi.nlm.nih.gov/35927444